F. Eggimann

发表

Draft Genome Sequences of Three Actinobacteria Strains Presenting New Candidate Organisms with High Potentials for Specific P450 Cytochromes

V. Urlacher, Y. Vainshtein, A. Vogel, 2017, Genome Announcements.

Human UDP-glucuronosyltransferase UGT1A4 forms tertiary N-glucuronides predominately with the energetically less favored tautomer of substituted 1H-indazole (benzpyrazole)

M. Kittelmann, A. Fredenhagen, J. Kühnöl, 2017, Journal of Analytical Science and Technology.

Discovery and Characterization of Clinical Candidate LXE408 as a Kinetoplastid-Selective Proteasome Inhibitor for the Treatment of Leishmaniases

F. Supek, D. Caridha, Yen-Liang Chen, 2020, Journal of medicinal chemistry.

Design of A Metabolically Stable Tritium-Tracer of the PI3Kδ-Inhibitor CDZ173 (Leniolisib) as a Tool to Study Liver Metabolites

P. Bross, K. Litherland, S. Desrayaud, 2018, Helvetica Chimica Acta.

CYP27A1-dependent anti-melanoma activity of limonoid natural products targets mitochondrial metabolism.

Nathan T. Ross, Stephen M. Canham, John A. Tallarico, 2021, Cell chemical biology.

Human FMO2-based microbial whole-cell catalysts for drug metabolite synthesis

Martina Geier, Beat Wirz, Matthias Kittelmann, 2015, Microbial Cell Factories.

Production of Recombinant Human Aldehyde Oxidase in Escherichia coli and Optimization of Its Application for the Preparative Synthesis of Oxidized Drug Metabolites

Anton Glieder, Sandra Abad, Matthias Kittelmann, 2014 .

Machine-Directed Evolution of an Imine Reductase for Activity and Stereoselectivity

Richard A. Lewis, Eric J. Ma, M. Stoeckli, 2021, ACS Catalysis.

A novel cytochrome P450 mono‐oxygenase from Streptomyces platensis resembles activities of human drug metabolizing P450s

V. Urlacher, A. Vogel, S. Lütz, 2018, Biotechnology and bioengineering.

Disposition of asciminib, a potent BCR-ABL1 tyrosine kinase inhibitor, in healthy male subjects

J. Schoepfer, Imad Hanna, F. Hourcade‐Potelleret, 2020, Xenobiotica; the fate of foreign compounds in biological systems.

Identification of Three Novel Ring Expansion Metabolites of KAE609, a New Spiroindolone Agent for the Treatment of Malaria, in Rats, Dogs, and Humans

J. Mangold, O. Simon, H. Einolf, 2016, Drug Metabolism and Disposition.

Absorption, Distribution, Metabolism, and Excretion of the Oral Prostaglandin D2 Receptor 2 Antagonist Fevipiprant (QAW039) in Healthy Volunteers and In Vitro

R. Woessner, G. Camenisch, V. Erpenbeck, 2017, Drug Metabolism and Disposition.

Human xanthine oxidase recombinant in E. coli: A whole cell catalyst for preparative drug metabolite synthesis.

Beat Wirz, Matthias Kittelmann, Margit Winkler, 2016, Journal of biotechnology.