K. Agger

发表

Jarid2 binds mono-ubiquitylated H2A lysine 119 to mediate crosstalk between Polycomb complexes PRC1 and PRC2

Andrew R. Bassett, N. Brockdorff, E. Heard, 2016, Nature Communications.

A Novel Repressive E2F6 Complex Containing the Polycomb Group Protein, EPC1, That Interacts with EZH2 in a Proliferation-specific Manner*

C. Sardet, K. Helin, C. Attwooll, 2005, Journal of Biological Chemistry.

Conditional E2F1 activation in transgenic mice causes testicular atrophy and dysplasia mimicking human CIS

K. Helin, E. Santoni-Rugiu, O. Karlström, 2005, Oncogene.

COLD SPRING HARBOR SYMPOSIA ON QUANTITATIVE BIOLOGY VOLUME LXXIII

R. Young, R. Tjian, G. Daley, 2009 .

The KDM4/JMJD2 histone demethylases are required for hematopoietic stem cell maintenance.

K. Helin, K. D. Rasmussen, S. Miyagi, 2019, Blood.

Narrative Technique in the Works of the Pearl Poet

K. Agger, 2018 .

Histone lysine demethylases as targets for anticancer therapy

Kristian Helin, K. Helin, Karl Agger, 2013, Nature Reviews Drug Discovery.

Erasing the methyl mark: histone demethylases at the center of cellular differentiation and disease.

K. Helin, J. Christensen, P. Cloos, 2008, Genes & development.

cellular differentiation and disease Erasing the methyl mark : histone demethylases at the center of

K. Helin, J. Christensen, P. Cloos, 2008 .

The H3K27me3 demethylase JMJD3 contributes to the activation of the INK4A-ARF locus in response to oncogene- and stress-induced senescence.

K. Helin, J. Christensen, G. Andersen, 2009, Genes & development.

Coordinated regulation of transcriptional repression by the RBP2 H3K4 demethylase and Polycomb-Repressive Complex 2.

K. Helin, D. Pasini, K. Hansen, 2008, Genes & development.

RBP2 Belongs to a Family of Demethylases, Specific for Tri-and Dimethylated Lysine 4 on Histone 3

K. Helin, J. Rappsilber, D. Pasini, 2007, Cell.

The emerging functions of histone demethylases.

Kristian Helin, Jesper Christensen, K. Helin, 2008, Current opinion in genetics & development.

The Demethylase JMJD2C Localizes to H3K4me3-Positive Transcription Start Sites and Is Dispensable for Embryonic Development

Kristian Helin, Jesper Christensen, K. Helin, 2014, Molecular and Cellular Biology.

Regulation of stem cell differentiation by histone methyltransferases and demethylases.

K. Helin, D. Pasini, A. Bracken, 2008, Cold Spring Harbor symposia on quantitative biology.

UTX and JMJD3 are histone H3K27 demethylases involved in HOX gene regulation and development

I. Issaeva, K. Helin, J. Rappsilber, 2007, Nature.

The putative oncogene GASC1 demethylates tri- and dimethylated lysine 9 on histone H3

Juri Rappsilber, Kristian Helin, Jesper Christensen, 2006, Nature.

Inhibitors of histone demethylases.

K. Helin, M. Gajhede, R. Clausen, 2011, Bioorganic & medicinal chemistry.

DevelopmentIs Dispensable for Embryonic H3K4me3-Positive Transcription Start Sites The Demethylase JMJD2C Localizes to

K. Helin, M. T. Pedersen, J. Johansen, 2014 .

Positive Transcription Start Sites and Is Dispensable for

K. Helin, M. T. Pedersen, J. Johansen, 2014 .

Targeting RIOK2 ATPase activity leads to decreased protein synthesis and cell death in acute myeloid leukemia.

K. Helin, A. Lund, K. Andersen, 2021, Blood.

The Lysine Demethylase KDM5B Regulates Islet Function and Glucose Homeostasis

C. Ling, K. Helin, B. Holst, 2019, Journal of diabetes research.

Jmjd2/Kdm4 demethylases are required for expression of Il3ra and survival of acute myeloid leukemia cells

K. Helin, M. T. Pedersen, J. Johansen, 2016, Genes & development.

Continual removal of H3K9 promoter methylation by Jmjd2 demethylases is vital for ESC self‐renewal and early development

K. Helin, J. Nilsson, M. T. Pedersen, 2016, The EMBO journal.

The Lysine Demethylase KDM5B Regulates Islet Function and Glucose Homeostasis

C. Ling, K. Helin, B. Holst, 2019, Journal of diabetes research.

Universitet The Lysine Demethylase KDM 5 B Regulates Islet Function and Glucose Homeostasis

C. Ling, K. Helin, B. Holst, 2019 .

University of Groningen Jmjd 2 / Kdm 4 demethylases are required for expression of Il 3 ra and survival of acute myeloid leukemia cells

K. Helin, M. T. Pedersen, J. Johansen, 2017 .

Jmjd 2 / Kdm 4 demethylases are required for expression of Il 3 ra and survival of acute myeloid leukemia cells

K. Helin, M. T. Pedersen, J. Johansen, 2016 .

Vitamin C activates young LINE-1 elements in mouse embryonic stem cells via H3K9me3 demethylation

K. Helin, M. Branco, A. Ewing, 2023, bioRxiv.

Erasing the methyl mark: histone demethylases at the center of cellular differentiation and disease.

K. Helin, J. Christensen, P. Cloos, 2008, Genes & development.

The emerging functions of histone demethylases.

K. Helin, J. Christensen, P. Cloos, 2008, Current opinion in genetics & development.

TAK1 inhibition leads to RIPK1-dependent apoptosis in immune-activated cancers

T. Haystead, Tülin Tatar, S. Scarneo, 2024, Cell death & disease.