Thomas P. Markotan

发表

Antibody drug conjugates of cleavable amino-benzoyl-maytansinoids.

N. Papadopoulos, G. Thurston, Jing Shan, 2020, Bioorganic & medicinal chemistry.

Antibody drug conjugates of cleavable amino-alkyl and aryl maytansinoids.

Jason T Giurleo, N. Papadopoulos, G. Thurston, 2018, Bioorganic & medicinal chemistry.

A novel series of N-(azetidin-3-yl)-2-(heteroarylamino)acetamide CCR2 antagonists.

E. Opas, Z. Sui, Dana L. Johnson, 2013, Bioorganic & medicinal chemistry letters.

Overcoming hERG activity in the discovery of a series of 4-azetidinyl-1-aryl-cyclohexanes as CCR2 antagonists.

E. Opas, Z. Sui, Xuqing Zhang, 2011, Bioorganic & medicinal chemistry letters.

The discovery of novel cyclohexylamide CCR2 antagonists.

C. Molloy, E. Opas, Z. Sui, 2011, Bioorganic & medicinal chemistry letters.

Oxyguanidines. Part 2: Discovery of a novel orally active thrombin inhibitor through structure-based drug design and parallel synthesis.

B. Tomczuk, J. Spurlino, Tianbao Lu, 2004, Bioorganic & medicinal chemistry letters.

Discovery and clinical evaluation of 1-{N-[2-(amidinoaminooxy)ethyl]amino}carbonylmethyl-6-methyl-3-[2,2-difluoro-2-phenylethylamino]pyrazinone (RWJ-671818), a thrombin inhibitor with an oxyguanidine P1 motif.

B. Tomczuk, J. Spurlino, Tianbao Lu, 2010, Journal of medicinal chemistry.

Design, Synthesis, and Biological Evaluation of Novel Potent and Selective αvβ3/αvβ5 Integrin Dual Inhibitors with Improved Bioavailability. Selection of the Molecular Core

B. Tomczuk, Tianbao Lu, J. Marugan, 2005 .

7-fluoroindazoles as potent and selective inhibitors of factor Xa.

Mark R Player, D. Parks, Yu-Kai Lee, 2008, Journal of medicinal chemistry.

Structural Effects of C6 Substitution in 6-(4-(Dimethylamino)phenyl)fulvenes

C. A. Morales, M. Peterson, Jeff Strnad, 1999 .

Triazolopyridazines as tyrosine kinase

Tianbao Lu, M. Cummings, A. Maroney, 2006 .

Site-specific antibody conjugations using bacterial transglutaminase and the Diels-Alder cycloaddition reaction

C. Kyratsous, S. Degrado, H. S. Afsari, 2023, Cell Reports Physical Science.