K. Sakane

发表

Discovery of diphenylcarbamate derivatives as highly potent and selective IP receptor agonists: orally active prostacyclin mimetics. Part 3.

A. Tanaka, J. Seki, K. Hattori, 2005, Bioorganic & medicinal chemistry letters.

Structure-based de novo design of non-nucleoside adenosine deaminase inhibitors.

T. Kinoshita, Tadashi Terasaka, Katsuya Nakamura, 2003, Bioorganic & medicinal chemistry letters.

In Vitro Activities of a New Lipopeptide Antifungal Agent, FK463, against a Variety of Clinically Important Fungi

Koji Kawabata, F. Ikeda, T. Goto, 2000, Antimicrobial Agents and Chemotherapy.

Chryscandin, a novel peptidyl nucleoside antibiotic. II. Structure determination and synthesis.

H. Imanaka, M. Kohsaka, M. Yamashita, 1984, The Journal of antibiotics.

Asymmetric synthesis of FR165914: A novel β3-adrenergic agonist with a benzocycloheptene structure

T. Kinoshita, I. Nakanishi, K. Hattori, 1995 .

Anti-Helicobacter pylori agents. 5. 2-(Substituted guanidino)-4-arylthiazoles and aryloxazole analogues.

Y. Matsumoto, H. Takasugi, Y. Inoue, 2002, Journal of medicinal chemistry.

A novel synthesis of the pyrazolo[1,5-a]quinoline ring system. New N1-C2 bridged DNA gyrase inhibitors via a novel tandem 1,4-conjugate addition-Michael [3+2] annulation process

T. Kinoshita, H. Sasaki, D. Barrett, 1996 .

Novel adenosine A1 receptor antagonists. Synthesis and structure-activity relationships of a novel series of 3-(2-cyclohexenyl-3-oxo-2,3-dihydropyridazin-6-yl)-2-phenylpyrazolo[1,5 -a]pyridines.

Y. Tenda, K. Durkin, H. Itani, 2000, Bioorganic & medicinal chemistry.

Anti-Helicobacter pylori agents. 4. 2-(Substituted guanidino)-4-phenylthiazoles and some structurally rigid derivatives.

Y. Matsumoto, H. Takasugi, Y. Inoue, 2000, Journal of medicinal chemistry.

Design, synthesis and biological evaluation of a novel series of potent, orally active adenosine A1 receptor antagonists with high blood-brain barrier permeability.

Y. Tenda, Y. Tomishima, F. Takamura, 2001, Chemical & pharmaceutical bulletin.

A novel pyridazinone derivative as a nonprostanoid PGI2 agonist.

J. Seki, K. Hattori, K. Tsubaki, 2000, Bioorganic & Medicinal Chemistry Letters.

Anti-Helicobacter pylori Agents. Part 4. 2-(Substituted guanidino)-4-phenylthiazoles and Some Structurally Rigid Derivatives.

Y. Matsumoto, H. Takasugi, Y. Inoue, 2000 .

Orally active cephalosporins. Part 2: synthesis, structure-activity relationships and oral absorption of cephalosporins having a C-3 pyridyl side chain.

Y. Matsumoto, S. Matsumoto, K. Kawabata, 2000, Bioorganic & medicinal chemistry.

Alkylation of 1-(N-(Hydroxymethyl)-N-methylamino)-4-quinolones. An Improved Preparation of Intermediates for Novel Potent Tricyclic Quinolone Antibacterial Agents.

T. Kinoshita, H. Sasaki, D. Barrett, 1996 .

A novel [3 + 2] annulation: synthesis and X-ray crystallographic structure of a novel tetrahydropyrazolo[1,5-a] quinoline, an intermediate towards new tricyclic quinolone antibacterials

T. Kinoshita, H. Sasaki, D. Barrett, 1996 .

Synthesis and structure determination of FR109615, a new antifungal antibiotic.

K. Kawabata, S. Hashimoto, T. Iwamoto, 1990, The Journal of antibiotics.

Synthesis and antifungal activity of FR109615 analogs.

T. Kamimura, H. Ohki, K. Kawabata, 1991, The Journal of antibiotics.

A Concise, Practical Synthesis of the Pyrido[3,2,1-i,j]Cinnoline Ring System of Potent DNA Gyrase Inhibitors

H. Sasaki, D. Barrett, T. Terasawa, 1995 .

A Concise, Practical Synthesis of the Pyrido(3.2.1-ij)cinnoline Ring System of Potent DNA Gyrase Inhibitors.

H. Sasaki, D. Barrett, T. Terasawa, 2010 .

Synthesis and biological evaluation of novel 2-vinyl carbapenems. Remarkable DHP-1 stability of 1′-substituted analogs

T. Kamimura, K. Hattori, T. Chiba, 1996 .

Studies on β-lactam antibiotics. Synthesis and antibacterial activity of novel 1β-methylcarbapenems related to FR21818: 5-membered ring analogs

M. Sakurai, A. Tanaka, Y. Matsumoto, 1997 .

Epimerization Induced by a Remote Cationic Center in Potent New Carbapenems

T. Chiba, H. Azami, D. Barrett, 1997 .

Synthesis and antibacterial activity of FR21818, a new, potent 1β-methylcarbapenem

A. Tanaka, Y. Matsumoto, H. Sasaki, 1995 .

Studies on beta-lactam antibiotics. Synthesis and antibacterial activity of novel C-3 alkyne-substituted cephalosporins.

T. Kamimura, N. Yasuda, T. Takaya, 1997, The Journal of antibiotics.

Reaction of N -Nitroso-1,2,3,4-tetrahydroisoquinolines with Base. A New Method for the Conversion of 1,2,3,4-Tetrahydroisoquinolines into 3,4-Dihydroisoquinolines

E. Imoto, Y. Otsuji, K. Sakane, 1974 .

Studies of 7 beta-[2-(aminoaryl)acetamido]-cephalosporin derivatives. II. Synthesis and structure-activity relationships in the aminopyrimidine series.

J. Goto, T. Kamiya, K. Sakane, 1984, The Journal of antibiotics.

New reagents for controlled release of nitric oxide. Structure-stability relationships

I. Nakanishi, H. Takasugi, Masayuki Kato, 1996 .

Synthesis and biological properties of a novel cephalosporin FR86521 having potent activity against methicillin-resistant Staphylococcus aureus (MRSA)

Y. Matsumoto, S. Matsumoto, H. Ohki, 1999, The Journal of antibiotics.

Studies of 7 beta-[2-(aminoaryl)acetamido]-cephalosporin derivatives. III. Synthesis and structure-activity relationships in the aminothiadiazole series.

J. Goto, K. Sakane, T. Teraji, 1984, The Journal of antibiotics.

Synthesis and biological activity of 3-vinylthio- and 3-vinylthiomethylcephem derivatives.

H. Sasaki, N. Yasuda, T. Takaya, 1990, The Journal of antibiotics.

Anti-Helicobacter pylori agents. 3. 2-[(Arylalkyl)guanidino]-4-furylthiazoles.

Y. Matsumoto, H. Takasugi, K. Sakane, 1999, Journal of medicinal chemistry.

Structure activity relationships of synthetic antibiotic analogues of chryscandin.

H. Imanaka, M. Kohsaka, T. Komori, 1985, Journal of antibiotics (Tokyo. 1968).

Structure and total synthesis of chryscandin, a new antifungal antibiotic

H. Imanaka, M. Kohsaka, M. Yamashita, 1985 .

FK037, a new parenteral cephalosporin with a broad antibacterial spectrum: synthesis and antibacterial activity.

T. Kamimura, H. Ohki, S. Okuda, 1993, The Journal of antibiotics.

Studies on 3'-quaternary ammonium cephalosporins--III. Synthesis and antibacterial activity of 3'-(3-aminopyrazolium) cephalosporins.

T. Kamimura, H. Ohki, S. Okuda, 1997, Bioorganic & medicinal chemistry.

Studies of 7 beta-[2-(aminoaryl)acetamido]-cephalosporin derivatives. I. Synthesis and structure-activity relationships in the aminopyridine series.

J. Goto, T. Kamiya, K. Sakane, 1984, The Journal of antibiotics.

Synthesis of the water-soluble adenosine A1 receptor antagonist FR166124 through a novel sequential Horner-Emmons / isomerization reaction

T. Kinoshita, I. Nakanishi, K. Durkin, 1999 .

Discovery of FR166124, a novel water-soluble pyrazolo-[1,5-a]pyridine adenosine A1 receptor antagonist.

T. Kinoshita, Y. Tenda, K. Durkin, 1999, Bioorganic & medicinal chemistry letters.

Anti-Helicobacter pylori agents. 2. Structure activity relationships in a new series of 2-alkylguanidino-4-furylthiazoles.

Y. Matsumoto, H. Takasugi, K. Sakane, 1998, Bioorganic & medicinal chemistry letters.

Orally active cephalosporins: synthesis, structure-activity relationships and oral absorption of 3-[(E) and (Z)-2-substituted vinyl]-cephalosporins.

A. Ohki, Y. Matsumoto, S. Matsumoto, 2000, Bioorganic & medicinal chemistry.

Revised structure and the chemical transformations of FR900148.

N. Yasuda, K. Sakane, 1991, The Journal of antibiotics.

Discovery of new diphenyloxazole derivatives containing a pyrrolidine ring: orally active prostacyclin mimetics. Part 2.

J. Seki, K. Hattori, S. Koyama, 2005, Bioorganic & medicinal chemistry letters.

Studies on 3'-Quaternary Ammonium Cephalosporins II1)

T. Kamimura, H. Ohki, S. Okuda, 1995 .

New Reagents for Controlled Release of Nitric Oxide. Structure‐ Stability Relationships.

I. Nakanishi, H. Takasugi, Masayuki Kato, 1996 .

Discovery of diphenyloxazole and Ndelta-Z-ornithine derivatives as highly potent and selective human prostaglandin EP(4) receptor antagonists.

A. Tanaka, N. Fujii, Y. Tenda, 2005, Journal of medicinal chemistry.

[A new oral cephem, cefdinir: its structure-activity relationships and biological profile].

T. Takaya, K. Sakane, Y. Inamoto, 1992, The Japanese journal of antibiotics.