D. A. Singleton

发表

Mechanism of ene reactions of singlet oxygen. A two-step no-intermediate mechanism.

Andrew G. Leach, M. P. Meyer, K. Houk, 2003, Journal of the American Chemical Society.

Isotope Effects and the Mechanism of Photoredox-Promoted [2 + 2] Cycloadditions of Enones.

D. A. Singleton, Kai-Yuan Kuan, 2021, The Journal of organic chemistry.

Ir-Catalyzed ortho-Borylation of Phenols Directed by Substrate-Ligand Electrostatic Interactions: A Combined Experimental/in Silico Strategy for Optimizing Weak Interactions.

Milton R. Smith, B. Chattopadhyay, R. Maleczka, 2017, Journal of the American Chemical Society.

Enantioselective synthesis without discrete optically active additives.

L. Vo, D. A. Singleton, 2002, Journal of the American Chemical Society.

13C Kinetic Isotope Effects and the Mechanism of the Uncatalyzed Decarboxylation of Orotic Acid

Jeehiun K. Lee, P. Beak, B. Kim, 2000 .

Outer-Sphere Direction in Iridium C—H Borylation.

Milton R. Smith, B. Chattopadhyay, R. Maleczka, 2013 .

Dynamics and a Unified Understanding of Competitive [2,3]- and [1,2]-Sigmatropic Rearrangements Based on a Study of Ammonium Ylides

B. Biswas, Sean Collins, D. A. Singleton, 2014, Journal of the American Chemical Society.

Competition between reaction and intramolecular energy redistribution in solution: observation and nature of nonstatistical dynamics in the ozonolysis of vinyl ethers.

D. A. Singleton, L. M. M. Quijano, 2011, Journal of the American Chemical Society.

Vibrationally Hot and Cold Triplets. Sensitizer-Dependent Dynamics and Localized Vibrational Promotion of a Di-π-methane Rearrangement.

D. A. Singleton, Kai-Yuan Kuan, 2020, Journal of the American Chemical Society.

Experimental Geometry of the Epoxidation Transition State

K. Houk, D. Singleton, Jian Liu, 1997 .

Transition-state geometry measurements from (13)c isotope effects. The experimental transition state for the epoxidation of alkenes with oxaziridines.

C. Hang, T. Takeya, D. A. Singleton, 2009, Journal of the American Chemical Society.

Isotope effects and the mechanism of deoxygenation of epoxides with dichlorocarbene

Zhihong Wang, D. A. Singleton, 2005 .

Isotope effects and the mechanism of fragmentation of epoxy imino-1,3,4-oxadiazolines

Zhihong Wang, D. A. Singleton, 2005 .

Isotope effects and the distinction between synchronous, asynchronous, and stepwise Diels–Alder reactions

C. Hang, A. Thomas, S. R. Merrigan, 2001 .

Isotope effects and the experimental transition state for a prototypical thermal ene reaction

C. Hang, D. A. Singleton, 1999 .

Isotope effects for Lewis acid catalyzed Diels-Alder reactions. The experimental transition state

B. Beno, K. Houk, S. R. Merrigan, 1999 .

Stereochemical labeling at natural abundance. Stereochemistry, isotope effects, and mechanism of the Diels-Alder reaction of hexachlorocyclopentadiene with ethyl vinyl ether

A. Thomas, S. R. Merrigan, D. A. Singleton, 1999 .

Dynamically Complex [6+4] and [4+2] Cycloadditions in the Biosynthesis of Spinosyn A.

Hung‐wen Liu, Zhuo Chen, K. Houk, 2016, Journal of the American Chemical Society.

Isotope effects and the mechanism of an electron-transfer-catalyzed Diels-Alder reaction.

M. P. Meyer, O. Wiest, N. Saettel, 2002, Journal of the American Chemical Society.

Direct free-radical substitutions on allyl and vinyl halides using alkyl halides/hexabutylditin

D. A. Singleton, C. C. Huval, 1993 .

Isotope Effects and the Mechanism of Chlorotrimethylsilane-Mediated Addition of Cuprates to Enones

D. Frantz, D. A. Singleton, 2000 .

13C Kinetic Isotope Effects for the Addition of Lithium Dibutylcuprate to Cyclohexenone. Reductive Elimination Is Rate-Determining

J. Snyder, D. Frantz, D. A. Singleton, 1997 .

A conjunctive diquinane synthesis using a free-radical catalyzed intramolecular [3+2] methylenecyclopentane annulation

D. A. Singleton, C. C. Huval, 1994 .

Direct Free‐Radical Substitutions on Allyl and Vinyl Halides Using Alkyl Halides/Hexabutylditin.

D. A. Singleton, C. C. Huval, 1993 .

Bond Memory in Dynamically-Determined Stereoselectivity.

Graham C. Haug, Viet D Nguyen, V. Nguyen, 2019, Journal of the American Chemical Society.

Reactions of Alkynyldihaloboranes with 1,3-Dienes. 1,4-Alkynylborations and Stepwise Diels-Alder Reactions.

D. A. Singleton, S.‐W. Leung, 1997, Journal of Organic Chemistry.

An unprecedented electronic preference for the "meta" product in Diels-Alder reactions of ethynyldialkylboranes. [(Trimethylsilyl)ethynyl]-9-BBN as a reactive and versatile dienophile

D. A. Singleton, S.‐W. Leung, 1992 .

Dynamics and the failure of transition state theory in alkene hydroboration.

Yatsandra Oyola, D. A. Singleton, 2009, Journal of the American Chemical Society.

3‐Acetoxy‐2‐trimethylsilylmethyl‐1‐propene

P. Vogel, M. Turks, D. Singleton, 2007 .

Outer-sphere direction in iridium C-H borylation.

Milton R. Smith, B. Chattopadhyay, R. Maleczka, 2012, Journal of the American Chemical Society.

Insights into the mechanism of flavoprotein-catalyzed amine oxidation from nitrogen isotope effects on the reaction of N-methyltryptophan oxidase.

W. Cleland, Mark A. Anderson, P. Fitzpatrick, 2007, Biochemistry.

Energy-labeling and –read-out of reactive intermediates in solution enabled by energy-dependent reaction selectivity

Hiroaki Kurouchi, D. A. Singleton, 2017, Nature Chemistry.

Electronic effects in iridium C-H borylations: insights from unencumbered substrates and variation of boryl ligand substituents.

Sean M. Preshlock, Milton R. Smith, R. Staples, 2010, Chemical communications.

Isotope effects and the nature of stereo- and regioselectivity in hydroaminations of vinylarenes catalyzed by palladium(ii)-diphosphine complexes.

L. Vo, D. A. Singleton, 2004, Organic letters.

A Case Study of the Mechanism of Alcohol-Mediated Morita Baylis–Hillman Reactions. The Importance of Experimental Observations

D. Singleton, R. E. Plata, D. A. Singleton, 2015, Journal of the American Chemical Society.

In situ formation of alkenyl- and alkynylboranes for Diels—Alder reactions by boron—silicon exchange with alkenyl- and alkynylsilanes

D. A. Singleton, S.‐W. Leung, 1997 .

In situ formation of vinylboranes for use in Diels Alder reactions. An easy one-pot Diels-Alder synthesis of cyclohexenols

D. A. Singleton, G. Ndip, J. P. Martínez, 1992 .

Vinylboranes are omniphilic dienophiles. Some unusual and useful properties of vinylboranes in diels-alder reactions

D. A. Singleton, J. P. Martínez, J. V. Watson, 1992 .

2-Trimethylsilylvinylboranes: highly reactive and selective diels-alder equivalents of 2-trimethylsilylvinyl alcohol and acetylene

D. A. Singleton, J. P. Martínez, 1991 .

High reactivity, regioselectivity, and endo-stereoselectivity of vinyl boranes in Diels-Alder reactions

D. A. Singleton, J. P. Martínez, 1990 .

An Unprecedented Electronic Preference for the “Meta” Product in Diels- Alder Reactions of Ethynyldialkylboranes. ((Trimethylsilyl)ethynyl)-9- BBN as a Reactive and Versatile Dienophile.

D. A. Singleton, S.‐W. Leung, 2010 .

9‐Vinyl‐9‐borabicyclo[3.3.1]nonane

D. A. Singleton, 2001 .

Vinylboranes as Diels-Alder Dienophiles

D. A. Singleton, 1997 .

Diels-Alder reactions of 2-alkenylboranes and cis-1-alkenylboranes. Anomalous selectivity that allows a choice of regiochemistry

D. A. Singleton, J. P. Martínez, Kyeongsook Kim, 1993 .

Reactions of Alkynyldihaloboranes with 1,3-Dienes. 1,4- Alkylnylborations and Stepwise Diels-Alder Reactions.

D. A. Singleton, S.‐W. Leung, 1997 .

Acrolein acetals as allyl cation precursors in the ionic Diels-Alder reaction

P. G. Gassman, S. P. Chavan, D. A. Singleton, 1987 .

Carbometalations of simple alkenes with allyldibromoborane.

D. Frantz, D. A. Singleton, 1999, Organic letters.

Exo-selective Diels-Alder reactions of vinylazepines. Origin of divergent stereoselectivity in Diels-Alder reactions of vinylazepines, vinylpiperideines, and vinylcycloalkenes.

G. Sulikowski, J. Reibenspies, Matthew D. Tallant, 2003, The Journal of organic chemistry.

Distinction between aminium cation radical and protic acid catalyzed Diels-Alder reactions

P. G. Gassman, D. A. Singleton, 1984 .

2‐Methoxy‐1‐phenylthio‐1,3‐butadiene

D. A. Singleton, 2001 .

Mechanism and origin of stereoselectivity in Lewis acid catalyzed [2 + 2] cycloadditions of ketenes with aldehydes.

D. Romo, Ying-Chuan Wang, D. A. Singleton, 2002, Angewandte Chemie.

Isotope effects and the mechanism of epoxidation of cyclohexenone with tert-butyl hydroperoxide.

Chad F. Christian, M. Szymanski, T. Takeya, 2007, The Journal of organic chemistry.

High-Precision Simultaneous Determination of Multiple Small Kinetic Isotope Effects at Natural Abundance

A. Thomas, D. A. Singleton, Allen A. Thomas, 1995 .

Isotope effects and heavy-atom tunneling in the Roush allylboration of aldehydes.

Mathew J. Vetticatt, D. A. Singleton, 2012, Organic letters.

Reinvestigation of the Isotope Effects for the Claisen and Aromatic Claisen Rearrangements: The Nature of the Claisen Transition States

M. P. Meyer, A. DelMonte, D. A. Singleton, 1999 .

Isotope effects and the mechanism of palladium-catalyzed allylic alkylation

Chad F. Christian, D. A. Singleton, 2005 .

N-alkyl-4-(N′,N′-dialkylamino)pyridinium salts: thermally stable phase transfer catalysts for nucleophilic aromatic displacement

D. Brunelle, D. A. Singleton, 1984 .

Methyl 3‐Nitroacrylate

D. A. Singleton, 2001 .

Failure and Redemption of Statistical and Nonstatistical Rate Theories in the Hydroboration of Alkenes.

D. A. Singleton, Johnathan O Bailey, 2017, Journal of the American Chemical Society.

Experimental and Theoretical Kinetic Isotope Effects for Asymmetric Dihydroxylation. Evidence Supporting a Rate-Limiting “(3 + 2)” Cycloaddition

K. Houk, K. Sharpless, D. Singleton, 1997 .

Intramolecular Diels-Alder reactions of vinylboranes. A highly stereoselective two-step decalin synthesis

Yu-Kai Lee, D. A. Singleton, 1995 .

Isotope-induced desymmetrization can mimic isotopic perturbation of equilibria. On the symmetry of bromonium ions and hydrogen bonds.

D. A. Singleton, Xavier S Bogle, 2011, Journal of the American Chemical Society.

Intramolecular Diels‐Alder Reactions of Vinylboranes. A Highly Stereoselective Two‐Step Decalin Synthesis.

Yu-Kai Lee, D. A. Singleton, 1995 .

Tuning of Vinylborane Dienophilicity. Optimization of Reactivity, Regioselectivity, endo-Stereoselectivity, and Reagent Stability

D. A. Singleton, G. Ndip, J. P. Martínez, 1992 .

A [4 + 3] transition state for a [4 + 2] cycloaddition. A new secondary orbital interaction in Diels-Alder reactions

D. A. Singleton, 1992 .

Control of regiospecificity in ionic Diels―Alder reactions: the use of allylic alcohols and allylic ethers as precursors of dienophilic allyl cations

P. G. Gassman, D. A. Singleton, 1986 .

Cycloalkenylboranes as Highly Reactive and Selective Diels-Alder Dienophiles. A Simple Synthesis of Bridgehead Bicyclic Alcohols.

Yu-Kai Lee, D. A. Singleton, 1997, The Journal of organic chemistry.

Solvation Dynamics and the Nature of Reaction Barriers and Ion-Pair Intermediates in Carbocation Reactions.

D. A. Singleton, V. A. Roytman, 2020, Journal of the American Chemical Society.

Reaction removal of polychlorinated biphenyls from transformer oil: treatment of contaminated oil with poly(ethylene glycol)/potassium hydroxide.

A. K. Mendiratta, Daniel Joseph Brunelle, Ashok K. Mendiratta, 1985, Environmental science & technology.

Isotope Effects, Dynamic Matching, and Solvent Dynamics in a Wittig Reaction. Betaines as Bypassed Intermediates

Zhuo Chen, D. A. Singleton, Jack R. Waas, 2014, Journal of the American Chemical Society.

A few molecules can control the enantiomeric outcome. Evidence supporting absolute asymmetric synthesis using the Soai asymmetric autocatalysis.

D. Singleton, L. Vo, D. A. Singleton, 2003, Organic letters.

2‐Methoxy‐3‐phenylthio‐1,3‐butadiene

D. A. Singleton, 2001 .

Methylenecyclopropanecarboxylates and -dicarboxylates, efficient reagents for the [3 + 2] methylenecyclopentane annulation of unactivated and electron-rich alkenes

E. Priestley, K. Church, D. A. Singleton, 1991 .

Experimental evidence for heavy-atom tunneling in the ring-opening of cyclopropylcarbinyl radical from intramolecular 12C/13C kinetic isotope effects.

A. Datta, Xue Zhang, D. Hrovat, 2010, Journal of the American Chemical Society.

Isotope effects and the mechanism of allylic hydroxylation of alkenes with selenium dioxide.

C. Hang, D. A. Singleton, 2000, The Journal of organic chemistry.

Simultaneous Determination of Intermolecular and Intramolecular 13C and 2H Kinetic Isotope Effects at Natural Abundance

M. Szymanski, D. A. Singleton, 1999 .

13C and (2)H kinetic isotope effects and the mechanism of Lewis acid-catalyzed ene reactions of formaldehyde.

C. Hang, D. A. Singleton, 2000, The Journal of organic chemistry.

13C and 2H kinetic isotope effects and the mechanism of bromination of 1-pentene under synthetic conditions.

S. R. Merrigan, D. A. Singleton, 1999, Organic letters.

Separation of the primary and secondary kinetic isotope effects at a reactive center using starting material reactivities. Application to the FeCl3-Catalyzed oxidation of CH bonds with tert-butyl hydroperoxide

D. Barton, Jason A. Smith, S. R. Merrigan, 1999 .

Entropic intermediates and hidden rate-limiting steps in seemingly concerted cycloadditions. Observation, prediction, and origin of an isotope effect on recrossing.

Eugene E. Kwan, Ollie M Gonzalez-James, D. Singleton, 2012, Journal of the American Chemical Society.

Catalytic stereocontrol of a radical cyclization

M. J. Lucero, K. Church, D. A. Singleton, 1990 .

Acid-catalyzed intramolecular Diels-Alder reactions. The cycloaddition of allyl cations to 1,3-dienes

P. G. Gassman, D. A. Singleton, 1984 .

Control elements in dynamically determined selectivity on a bifurcating surface.

M. Harmata, Jacqueline B Thomas, D. A. Singleton, 2008, Journal of the American Chemical Society.

Isotope effect, mechanism, and origin of catalysis in the decarboxylation of mandelylthiamin.

Ollie M Gonzalez-James, D. A. Singleton, 2010, Journal of the American Chemical Society.

Vinylboranes as trans-dihydroxyethylene equivalents for diels-alder reactions

A. Redman, D. A. Singleton, 1994 .

Comment on “Activation of methane to CH3+: A selective industrial route to methanesulfonic acid”

D. A. Singleton, V. A. Roytman, 2019, Science.

Mechanistic Studies of Formal Thioboration Reactions of Alkynes.

P. Mayer, S. Blum, G. Berionni, 2017, The Journal of organic chemistry.

Destruction/removal of polychlorinated biphenyls from non-polar media. Reaction of PCB with poly (ethylene glycol)/KOH

D. Brunelle, D. A. Singleton, 1983 .

Vinylboranes as trans-Dihydroxyethylene Equivalents for Diels-Alder Reactions.

A. Redman, D. A. Singleton, 1994 .

Free-radical mediated [3+2] methylenecyclopentane annulations of electron-poor alkenes

K. Church, D. A. Singleton, C. C. Huval, 1994 .

"Concerted" transition state, stepwise mechanism. Dynamics effects in C2-C6 enyne allene cyclizations.

Chad F. Christian, M. Lipton, D. A. Singleton, 2005, Journal of the American Chemical Society.

Controlling Selectivity by Controlling the Path of Trajectories

B. Biswas, D. A. Singleton, 2015, Journal of the American Chemical Society.

Dynamics and the Regiochemistry of Nitration of Toluene.

D. A. Singleton, Yexenia Nieves-Quinones, 2016, Journal of the American Chemical Society.

Controlling Selectivity by Controlling Energy Partitioning in a Thermal Reaction in Solution.

Hiroaki Kurouchi, D. A. Singleton, Ivonne L Andujar-De Sanctis, 2016, Journal of the American Chemical Society.

Recrossing and dynamic matching effects on selectivity in a Diels-Alder reaction.

Zhihong Wang, D. A. Singleton, Jennifer S. Hirschi, 2009, Angewandte Chemie.

Energy Read-out as a Probe of Kinetically Hidden Transition States.

D. A. Singleton, Scheherzad Alvi, 2021, Organic Letters.

Evidence for a Concerted Mechanism in a Palladium Trimethylenemethane Cycloaddition

D. A. Singleton, Brian E. Schulmeier, 1999 .

Synchronous or Asynchronous? An “Experimental” Transition State from a Direct Comparison of Experimental and Theoretical Kinetic Isotope Effects for a Diels−Alder Reaction

K. Houk, B. Beno, D. Singleton, 1996 .

CATALYSIS BY TEMPORARY COVALENT ACTIVATION. A NOVEL CATALYSIS OF UNACTIVATED DIELS-ALDER REACTIONS

Yu-Kai Lee, D. A. Singleton, S.‐W. Leung, 1997 .

Concert along the Edge: Dynamics and the Nature of the Border between General and Specific Acid-Base Catalysis.

D. A. Singleton, Hannah R. Aziz, 2017, Journal of the American Chemical Society.

Newtonian kinetic isotope effects. Observation, prediction, and origin of heavy-atom dynamic isotope effects.

D. A. Singleton, Jennifer S. Hirschi, K. K. Kelly, 2009, Journal of the American Chemical Society.

The normal range for secondary Swain-Schaad exponents without tunneling or kinetic complexity.

D. A. Singleton, Jennifer S. Hirschi, 2005, Journal of the American Chemical Society.

Phenomenon of optical self-purification of chiral non-racemic compounds.

Manabu Yasumoto, D. Singleton, V. Soloshonok, 2007, Journal of the American Chemical Society.

Dynamic effects on the periselectivity, rate, isotope effects, and mechanism of cycloadditions of ketenes with cyclopentadiene.

C. Hang, Daniel A Singleton, Chao Hang, 2006, Journal of the American Chemical Society.

A new form of kinetic isotope effect. Dynamic effects on isotopic selectivity and regioselectivity.

Michael J Szymanski, C. Hang, Daniel A Singleton, 2003, Journal of the American Chemical Society.

Isotope effects and the nature of enantioselectivity in the shi epoxidation. The importance of asynchronicity.

Zhihong Wang, D. A. Singleton, 2005, Journal of the American Chemical Society.

Versatile [3 + 2] methylenecyclopentane annulations of unactivated and electron-rich olefins with [(trimethylsilyl)methylene]cyclopropanedicarboxylates

D. A. Singleton, C. C. Huval, 1994 .

Mechanism and origin of enantioselectivity in the Rh2(OAc)(DPTI)3-catalyzed cyclopropenation of alkynes.

D. Nowlan, D. A. Singleton, 2005, Journal of the American Chemical Society.

[3 + 2] Methylenecyclopentane annulations of unactivated and electron-rich olefins with 2-(phenylsulfonyl)-1-methylenecyclopropanes

K. Church, D. A. Singleton, 1990 .

(3 + 2)Methylenecyclopentane Annulations of Unactivated and Electron- Rich Olefins with 2-(Phenylsulfonyl)-1-methylenecyclopropanes.

K. Church, D. A. Singleton, 1991 .

Silyl group-transfer-mediated serial Michael additions

P. Klimko, D. A. Singleton, 1992 .

Ir-Catalyzed ortho-Borylation of Phenols Directed by Substrate-Ligand Electrostatic Interactions: A Combined Experimental/in Silico Strategy for Optimizing Weak Interactions.

Milton R. Smith, B. Chattopadhyay, R. Maleczka, 2017, Journal of the American Chemical Society.

Dynamically Complex [6+4] and [4+2] Cycloadditions in the Biosynthesis of Spinosyn A.

Hung‐wen Liu, Zhuo Chen, K. Houk, 2016, Journal of the American Chemical Society.

Energy-labeling and –read-out of reactive intermediates in solution enabled by energy-dependent reaction selectivity

Hiroaki Kurouchi, D. A. Singleton, 2017, Nature Chemistry.

Racing carbon atoms. Atomic motion reaction coordinates and structural effects on Newtonian kinetic isotope effects.

D. A. Singleton, Ivonne L Andujar-De Sanctis, 2012, Organic letters.

Isotope effects and the nature of selectivity in rhodium-catalyzed cyclopropanations.

D. Nowlan, H. Davies, T. Gregg, 2003, Journal of the American Chemical Society.