R. Robert

发表

Cystic fibrosis transmembrane conductance regulator trafficking modulates the barrier function of airway epithelial cell monolayers

D. Gruenert, J. Liao, J. Hanrahan, 2010, The Journal of physiology.

Cigarette smoke activates CFTR through ROS-stimulated cAMP signaling in human bronchial epithelial cells.

David Y. Thomas, G. Cosa, Alexandre Cloutier, 2018, American journal of physiology. Cell physiology.

Discovery of alpha-aminoazaheterocycle-methylglyoxal adducts as a new class of high affinity inhibitors of CFTR chloride channels.

J. Décout, F. Bossard, C. Gauthier, 2007 .

Latonduine analogues restore F508del-CFTR trafficking through the modulation of PARP-3 and PARP-16 activity.

Andersen, David Y. Thomas, G. Carlile, 2016 .

Role of the cystic fibrosis transmembrane conductance channel in human airway smooth muscle.

J. Hanrahan, Muhannad Hassan, James G. Martin, 2009, American journal of respiratory cell and molecular biology.

Cystic fibrosis transmembrane conductance regulator is expressed in mucin granules from Calu-3 and primary human airway epithelial cells.

S. Fahrenkrug, J. Hanrahan, P. Ferraro, 2013, American journal of respiratory cell and molecular biology.

Disruption of CFTR chloride channel alters mechanical properties and cAMP‐dependent Cl− transport of mouse aortic smooth muscle cells

C. Norez, F. Becq, R. Robert, 2005, The Journal of physiology.

Ouabain Mimics Low Temperature Rescue of F508del-CFTR in Cystic Fibrosis Epithelial Cells

Alberto Luini, Annamaria Carissimo, Donglei Zhang, 2012, Front. Pharmacol..

Enhanced Ca2+ entry due to Orai1 plasma membrane insertion increases IL‐8 secretion by cystic fibrosis airways

B. Rappaz, David Y. Thomas, A. Evagelidis, 2011, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Large pH oscillations promote host defense against human airways infection

Asmahan Abu-Arish, Yishan Luo, J. Liao, 2021, The Journal of experimental medicine.

Discovery of α-Aminoazaheterocycle-Methylglyoxal Adducts as a New Class of High-Affinity Inhibitors of Cystic Fibrosis Transmembrane Conductance Regulator Chloride Channels

J. Décout, F. Bossard, C. Gauthier, 2007, Journal of Pharmacology and Experimental Therapeutics.

Decreasing Poly(ADP-Ribose) Polymerase Activity Restores ΔF508 CFTR Trafficking

David Y. Thomas, G. Carlile, J. Liao, 2012, Front. Pharmacol..

Latonduine Analogs Restore F508del–Cystic Fibrosis Transmembrane Conductance Regulator Trafficking through the Modulation of Poly-ADP Ribose Polymerase 3 and Poly-ADP Ribose Polymerase 16 Activity

David Y. Thomas, G. Carlile, R. Solari, 2016, Molecular Pharmacology.

Expression and function of cystic fibrosis transmembrane conductance regulator in rat intrapulmonary arteries

C. Guibert, J. Savineau, C. Norez, 2007, European Respiratory Journal.

Evidence that CFTR is expressed in rat tracheal smooth muscle cells and contributes to bronchodilation

C. Guibert, C. Norez, C. Vandebrouck, 2006, Respiratory research.

Bicarbonate‐dependent chloride transport drives fluid secretion by the human airway epithelial cell line Calu‐3

S. Fahrenkrug, J. Liao, J. Hanrahan, 2012, The Journal of physiology.

Anion secretion by a model epithelium: more lessons from Calu‐3

J. Liao, J. Hanrahan, J. Shan, 2011, Acta physiologica.

A novel triple combination of pharmacological chaperones improves F508del-CFTR correction

David Y. Thomas, S. Radinovic, G. Carlile, 2018, Scientific Reports.

Structural Analog of Sildenafil Identified as a Novel Corrector of the F508del-CFTR Trafficking Defect

Donglei Zhang, David Y. Thomas, Donglei Zhang, 2008, Molecular Pharmacology.

Low free drug concentration prevents inhibition of F508del CFTR functional expression by the potentiator VX‐770 (ivacaftor)

David Y. Thomas, G. Carlile, Yishan Luo, 2016, British journal of pharmacology.

Identification of a NBD1-binding pharmacological chaperone that corrects the trafficking defect of F508del-CFTR.

David Y. Thomas, G. Carlile, J. Liao, 2011, Chemistry & biology.

Lack of CFTR in Skeletal Muscle Predisposes to Muscle Wasting and Diaphragm Muscle Pump Failure in Cystic Fibrosis Mice

D. Radzioch, A. Demoule, A. Comtois, 2009, PLoS genetics.

Ibuprofen rescues mutant cystic fibrosis transmembrane conductance regulator trafficking.

David Y. Thomas, D. Rotin, G. Carlile, 2015, Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society.

Correction of the ΔPhe508 Cystic Fibrosis Transmembrane Conductance Regulator Trafficking Defect by the Bioavailable Compound Glafenine

Bart Kus, David Y. Thomas, M. Wilke, 2010, Molecular Pharmacology.

Regulation of the Cystic Fibrosis Transmembrane Conductance Regulator Channel by β-Adrenergic Agonists and Vasoactive Intestinal Peptide in Rat Smooth Muscle Cells and Its Role in Vasorelaxation*

A. Kitzis, A. Cantereau, C. Norez, 2004, Journal of Biological Chemistry.

A novel triple combination of pharmacological chaperones improves F508del-CFTR correction

David Y. Thomas, S. Radinovic, G. Carlile, 2018, Scientific Reports.

Correction of F508del-CFTR trafficking by the sponge alkaloid latonduine is modulated by interaction with PARP.

Roger G. Linington, David E. Williams, C. A. Gray, 2012, Chemistry & biology.

Hsp70 and DNAJA2 limit CFTR levels through degradation

Jason C. Young, A. Shrier, Patrick Kim Chiaw, 2019, PloS one.