F. Grellepois

发表

Enantiopure β3-Trifluoromethyl-β3-homoalanine Derivatives: Coupling with Boc-Protected Amino Acids and Conformational Studies of Peptides in Solid State

F. Grellepois, Nathalie Saraiva Rosa, 2022, Synthesis.

α-Trifluoromethylated tertiary homoallylic amines: diastereoselective synthesis and conversion into β-aminoesters, γ- and δ-aminoalcohols, azetidines and pyrrolidines.

F. Grellepois, Nathalie Saraiva Rosa, Abdelkhalek Ben Jamaa, 2017, Organic & biomolecular chemistry.

Enantiopure trifluoromethylated β(3,3)-amino acids: synthesis by asymmetric Reformatsky reaction with stable analogues of trifluoromethyl N-tert-butanesulfinylketoimines and incorporation into α/β-peptides.

F. Grellepois, 2013, The Journal of organic chemistry.

Diastereoselective Addition of Organomagnesium and Organolithium Reagents to Chiral Trifluoromethyl N‐tert‐Butanesulfinyl Hemiaminals

A. Gassama, F. Grellepois, A. Jamaa, 2013 .

First synthesis of 10 alpha-(trifluoromethyl)deoxoartemisinin.

B. Crousse, D. Bonnet-Delpon, J. Bégué, 2002, Organic letters.

Anhydrodihydroartemisinin and its 10-trifluoromethyl analogue: access to novel d-ring-contracted artemisinin trifluoromethyl ketones.

B. Crousse, D. Bonnet-Delpon, J. Bégué, 2002, The Journal of organic chemistry.

cis-Dihydroxylated α-Trifluoromethylated N,O-Acetal from l-Tartaric Acid: Synthesis of Tetrasubstituted Stereocenter via Diastereoselective Pictet-Spengler Cyclization of N-Acyliminium Ions.

E. Riguet, Mohammed Latrache, F. Grellepois, 2020, The Journal of organic chemistry.

Fluoro artemisinins: difluoromethylene ketones.

B. Crousse, D. Bonnet-Delpon, J. Bégué, 2001, The Journal of organic chemistry.

Synthesis of Enantiopure 2-Aryl(Alkyl)-2-trifluoromethyl-Substituted Morpholines and Oxazepanes

C. Portella, F. Grellepois, J. Nonnenmacher, 2009 .

Enantiomerically pure 2-aryl(alkyl)-2-trifluoromethylaziridines: synthesis and ring opening with selected O- and N-nucleophiles.

F. Lachaud, C. Portella, F. Grellepois, 2011, Organic & biomolecular chemistry.

Diastereoselective Ritter-like Reaction on Cyclic Trifluoromethylated N,O-Acetals Derived from l-Tartaric Acid.

F. Grellepois, Abdelkhalek Ben Jamaa, 2017, The Journal of organic chemistry.

A [3,3]-sigmatropic process catalysed by acetate. The decarboxylative Claisen rearrangement

D. Bourgeois, D. Craig, D. M. Mountford, 2006 .

Decarboxylative Claisen rearrangement reactions of allylic tosylmalonate esters.

D. Craig, F. Grellepois, 2005, Organic letters.

New three-step domino reaction, "thiophilic addition-beta-elimination of fluoride-[3,3] sigmatropic rearrangement": Synthesis of alpha-allylic and alpha,alpha-bis(allylic) alpha-trifluoromethyl dithioesters.

Yu. G. Shermolovich, V. Timoshenko, C. Portella, 2006, Organic letters.

Synthesis of new artemisinin-derived dimers by self-cross-metathesis reaction.

B. Crousse, D. Bonnet-Delpon, J. Bégué, 2005, Organic letters.

1-(Trifluoromethyl)cyclopent-3-enecarboxylic Acid Derivatives: Platforms for Bifunctional Cyclic Trifluoromethyl Building Blocks

C. Portella, F. Grellepois, Nicolas Coia, 2012 .

Facile Conversion of Dithioestersinto Carboxylic Acids or Esters Using Alkaline HydrogenPeroxide

C. Portella, F. Grellepois, 2008 .

Organocatalytic enantioselective allylic alkylation of α-aryl γ-lactones: an approach to densely functionalized quaternary stereocentres.

E. Riguet, F. Grellepois, Morgane Mando, 2020, Chemical communications.

Synthesis and Study of Antioxidant Activities of trans-(-)-Clovamide Derivatives

A. Gassama, C. Lavaud, S. Sarr, 2018 .

Orally active antimalarials: hydrolytically stable derivatives of 10-trifluoromethyl anhydrodihydroartemisinin.

B. Pradines, Sébastien Charneau, W. Charman, 2004, Journal of medicinal chemistry.

Asymmetric decarboxylative Claisen rearrangement reactions of sulfoximine-substituted allylic tosylacetic esters.

A. White, D. Craig, F. Grellepois, 2005, The Journal of organic chemistry.

Design, Synthesis and Antimalarial Activity of Trifluoromethylartemisinin–Mefloquine Dual Molecules

P. Grellier, D. Bonnet-Delpon, J. Bégué, 2005, Chembiochem : a European journal of chemical biology.

Allylic bromination of anhydrodihydroartemisinin and of its 10-trifluoromethyl analogue: a new access to 16-substituted artemisinin derivatives

B. Crousse, D. Bonnet-Delpon, J. Bégué, 2002 .

Enantiopure quaternary alpha-trifluoromethyl-alpha-alkoxyaldehydes from L-tartaric acid derived ketoamides.

C. Portella, F. Massicot, F. Grellepois, 2008, The Journal of organic chemistry.

Thiophilic nucleophilic trifluoromethylation of α-substituted dithioesters. Access to S-trifluoromethyl ketene dithioacetals and their reactivity with electrophilic species

V. Timoshenko, C. Portella, F. Grellepois, 2012 .

Thiophilic Nucleophilic Trifluoromethylation of α-Substituted Dithioesters. Access to S-Trifluoromethyl Ketene Dithioacetals and Their Reactivity with Electrophilic Species.

V. Timoshenko, C. Portella, F. Grellepois, 2012 .

Perfluoroketene dithioacetals and perfluorodithiocarboxylic acid derivatives: Versatile tools for organofluorine synthesis

M. Muzard, Yu. G. Shermolovich, C. Brulé, 2007 .

Multi-step reactions of N -monosubstituted (polyfluoroalkane)thioamides with alkyllithium reagents

Yu. G. Shermolovich, V. Timoshenko, A. N. Chernega, 2007 .

Dual thiophilic or carbophilic reactivity of N,N-dialkyl perfluorocarboxylic thioamides with organometallic reagents

Yu. G. Shermolovich, V. Timoshenko, C. Portella, 2006 .

New fused dithiabicyclic compounds from the reaction of N,N-dialkyl perfluorothioamides with allylmagnesium halides

Yu. G. Shermolovich, V. Timoshenko, E. Rusanov, 2010 .

Dual Thiophilic or Carbophilic Reactivity of N,N‐Dialkyl Perfluorocarboxylic Thioamides with Organometallic Reagents.

Yu. G. Shermolovich, V. Timoshenko, C. Portella, 2006 .

The role of the counterion and of silicon chelation in the selective mono(trifluoromethylation) of tartaric acid derived 1,4-diketones.

D. Harakat, C. Portella, F. Massicot, 2011, Chemistry.

Enantiopure 2‐(Trifluoromethyl)‐1,2,3,4‐tetrahydronaphthalene‐1,2‐diols from a Tartaric Acid Derived Scaffold

C. Portella, F. Massicot, F. Grellepois, 2010 .

Enantiopure Quaternary α-Trifluoromethyl-α-alkoxyaldehydes from L-Tartaric Acid Derived Ketoamides.

C. Portella, F. Massicot, F. Grellepois, 2009 .

Facile Conversion of Dithioesters into Carboxylic Acids or Esters Using Alkaline Hydrogen Peroxide.

F. Grellepois, C. Portella*, 2009 .

Enantiomerically pure 2-aryl(alkyl)-2-trifluoromethylaziridines: synthesis and ring opening with selected O- and N-nucleophiles.

F. Lachaud, F. Grellepois, J. Nonnenmacher, 2011, Organic & biomolecular chemistry.