Louise Bernier

发表

Synthesis of ( R )- and ( S )-α-trifluoromethyl propanoic acids via asymmetric hydrogenation followed by salt resolution

N. Sach, O. Fadeyi, R. Unwalla, 2016 .

Practical Kilogram Synthesis of (S)-1-Benzyl-4-Bromo-3-Methyl-1,2,3,6-Tetrahydropyridine

N. Sach, Ming Z. Chen, Vince M. Lombardo, 2021, Organic Process Research & Development.

Improved cyclization conditions to prepare 6-substituted pyrazolo[1,5-a]pyridines and pyrazolo[1,5-a]pyrazines using catalytic Ag(I) and Au(III) salts

N. Sach, M. Tran-Dube, S. Ninkovic, 2015 .

Visible-Light-Initiated Manganese Catalysis for C-H Alkylation of Heteroarenes: Applications and Mechanistic Studies.

N. Sach, Y. M. Fobian, Chulho Choi, 2017, Angewandte Chemie.

High-Throughput Ligand Screening Enables the Enantioselective Conjugate Borylation of Cyclobutenones to Access Synthetically Versatile Tertiary Cyclobutylboronates.

Rory M. McDonald, N. Sach, D. Hall, 2019, Angewandte Chemie.

High‐Throughput Ligand Screening Enables the Enantioselective Conjugate Borylation of Cyclobutenones to Access Synthetically Versatile Tertiary Cyclobutylboronates

N. Sach, D. Hall, W. Farrell, 2019, Angewandte Chemie.

Discovery of N-((3R,4R)-4-Fluoro-1-(6-((3-methoxy-1-methyl-1H-pyrazol-4-yl)amino)-9-methyl-9H-purin-2-yl)pyrrolidine-3-yl)acrylamide (PF-06747775) through Structure-Based Drug Design: A High Affinity Irreversible Inhibitor Targeting Oncogenic EGFR Mutants with Selectivity over Wild-Type EGFR.

Paolo Vicini, Deepak Dalvie, Chengyi Zhang, 2017, Journal of medicinal chemistry.

Catalytic Enantioselective Synthesis of a cis-β-Boronyl Cyclobutylcarboxyester Scaffold and Its Highly Diastereoselective Nickel/Photoredox Dual-Catalyzed Csp3–Csp2 Cross-Coupling to Access Elusive trans-β-Aryl/Heteroaryl Cyclobutylcarboxyesters

N. Sach, D. Hall, W. Farrell, 2020, ACS Catalysis.

Correction to “Catalytic Enantioselective Synthesis of a cis-β-Boronyl Cyclobutylcarboxyester Scaffold and Its Highly Diastereoselective Nickel/Photoredox Dual-Catalyzed Csp3–Csp2 Cross-Coupling to Access Elusive trans-β-Aryl/Heteroaryl Cyclobutylcarboxyesters”

N. Sach, D. Hall, M. Reese, 2021, ACS Catalysis.

Design and Synthesis of Functionally Active 5-Amino-6-Aryl Pyrrolopyrimidine Inhibitors of Hematopoietic Progenitor Kinase 1.

N. Sach, M. McTigue, Sergei L Timofeevski, 2023, Journal of medicinal chemistry.

Efficient resolution of oxidized cleland's reagent by C2-symmetric Boc-L-phenylalanyl esters

T. Mansour, Louise Bernier, C. Evans, 1997 .

Rhodium(III)-Catalyzed C-H Activation: Ligand-Controlled Regioselective Synthesis of 4-Methyl-Substituted Dihydroisoquinolones.

N. Sach, M. Tran-Dube, M. Collins, 2019, Organic letters.

Probing the chemical ‘reactome’ with high-throughput experimentation data

Jacquelyn L. Klug-McLeod, S. Berritt, Emma King-Smith, 2024, Nature Chemistry.