S. C. Hobbs

发表

ENANTIOMERIC SEPARATION OF A SERIES OF 1,4-BENZODIAZEPIN-2-ONE CCK B RECEPTOR ANTAGONISTS BEARING ACIDIC SUBSTITUENTS BY CHIRAL HPLC

H. Verrier, A. Watt, D. Rathbone, 1999 .

Potent, selective, water-soluble benzodiazepine-based CCKB receptor antagonists that contain lipophilic carboxylate surrogates

V. Matassa, S. Freedman, S. Fletcher, 1995 .

L-708,474: The C5-cyclohexyl analogue of L-365,260, a selective high affinity ligand for the CCKB/gastrin receptor

V. Matassa, S. Freedman, S. Fletcher, 1993 .

Derives de benzodiazepine

V. Matassa, S. Fletcher, K. Moore, 1993 .

6,7-Dihydro-2-benzothiophen-4(5H)-ones: a novel class of GABA-A alpha5 receptor inverse agonists.

G. Dawson, J. Atack, H. Broughton, 2002, Journal of medicinal chemistry.

Synthesis and serotonergic activity of 5-(oxadiazolyl)tryptamines: potent agonists for 5-HT1D receptors.

D. Middlemiss, V. Matassa, M. Beer, 1993, Journal of medicinal chemistry.

Total Synthesis and Determination of the Absolute Configuration of Epibatidine

R. Ball, H. Verrier, S. Fletcher, 1994 .

The synthesis of (+)- and (–)-epibatidine

S. Fletcher, R. Baker, P. Mitchell, 1993 .

Synthesis and biological activity of 3-[2-(dimethylamino)ethyl]-5-[(1,1-dioxo-5-methyl-1,2,5-thiadiazolidin- 2-yl)-methyl]-1H-indole and analogues: agonists for the 5-HT1D receptor.

R. Hargreaves, M. Beer, J. Stanton, 1994, Journal of medicinal chemistry.

3-(Piperazinylpropyl)indoles: selective, orally bioavailable h5-HT1D receptor agonists as potential antimigraine agents.

V. Matassa, M. Beer, J. Stanton, 1999, Journal of medicinal chemistry.

An orally bioavailable, functionally selective inverse agonist at the benzodiazepine site of GABAA alpha5 receptors with cognition enhancing properties.

G. Dawson, J. Atack, D. O'connor, 2004, Journal of medicinal chemistry.

Identification of a Novel, Selective GABAA α5 Receptor Inverse Agonist Which Enhances Cognition

G. Dawson, J. Atack, H. Broughton, 2003 .

Pharmacokinetics and metabolism studies on (3-tert-butyl-7-(5-methylisoxazol-3-yl)-2-(1-methyl-1H-1,2,4-triazol-5-ylmethoxy) pyrazolo[1,5-d][1,2,4]triazine, a functionally selective GABA(A) alpha5 inverse agonist for cognitive dysfunction.

Desmond O'Connor, Robert Maxey, J. Atack, 2006, Bioorganic & medicinal chemistry letters.