T. Konoike

发表

Synthesis and pharmacological properties of ureidomethylcarbamoylphenylketone derivatives. A new potent and subtype-selective nonpeptide CCK-B/gastrin receptor antagonist, S-0509.

R. Kiyama, M. Ishikawa, Y. Ishihara, 1997, Bioorganic & medicinal chemistry.

Synthesis of 1,4-diketones by oxidative coupling of ketone enolates with copper(II) chloride

T. Saegusa, T. Harada, Yoshihiko Ito, 1977 .

Reaction of ketone enolates with copper dichloride. Synthesis of 1,4-diketones

T. Saegusa, Yoshihiko Ito, T. Konoike, 1975 .

Enantioselective Total Synthesis of (+)-6-epi-Mevinolin and Its Analogs. Efficient Construction of the Hexahydronaphthalene Moiety by High Pressure-Promoted Intramolecular Diels−Alder Reaction of (R,2Z,8E,10E)-1-[(tert-Butyldimethylsilyl)oxy]-6-methyl-2,8,10-dodecatrien-4-one

T. Konoike, Y. Araki, 1997 .

Design, synthesis and pharmacological evaluation of 3-benzylazetidine-2-one-based human chymase inhibitors.

Y. Aoyama, N. Naya, M. Nakajima, 2001, Bioorganic & medicinal chemistry.

Synthesis of 1,4-diketones by the reaction of silyl enol ether with silver oxide. Regiospecific formation of silver(I) enolate intermediates

T. Saegusa, T. Konoike, Y. Ito, 1975 .

π-Facial selection in intermolecular Diels-Alder reactions: total syntheses of (+)-actinobolin and (+)-5, 6, 10-triepi-actinobolin.

J. Springer, A. Kozikowski, T. Konoike, 1987 .

A total synthesis of actinobolin via the intermolecular Diels–Alder reaction of a threonine-derived diene

A. Kozikowski, T. Konoike, T. Nieduzak, 1986 .

Synthesis and biological properties of 7 beta-[(Z)-2-(2-amino-4-thiazolyl)-4-carboxy-2-butenoylamino]-3-cephem- 4-carboxylic acid (7432-S), a new oral cephem antibiotic.

Y. Hamashima, T. Yoshida, T. Konoike, 1987, The Journal of antibiotics.

Organometallics in organic synthesis. Applications of a new diorganozinc reaction to the synthesis of C-glycosyl compounds with evidence for an oxonium-ion mechanism.

A. Kozikowski, A. Ritter, T. Konoike, 1987, Carbohydrate research.

Synthesis and structure-activity relationships of a new class of 1-oxacephem-based human chymase inhibitors.

Y. Aoyama, N. Naya, M. Nakajima, 2000, Bioorganic & medicinal chemistry letters.

New route to 3-(substituted) methyl 1-oxa- and (1-thia)cephems from 3-exomethylene intermediates via sulfenyl chloride adducts

W. Nagata, T. Konoike, M. Yoshioka, 1983 .

Inhibition of serine proteases: activity of 1,3-diazetidine-2,4-diones.

Y. Aoyama, N. Naya, M. Nakajima, 2001, Bioorganic & medicinal chemistry letters.

Carbapenem and penem antibiotics. VII. Synthesis and antibacterial activity of 1 beta-methyl-2-(quaternary heteroaromatic-thiomethyl) carbapenems.

T. Yoshida, Y. Kimura, M. Imuta, 1991, Chemical & pharmaceutical bulletin.

Photoinduced Reactions. LXXIII. Solvent Dependence in the Photochemical Reaction of α-Nitroepoxides

I. Saito, T. Matsuura, T. Konoike, 1973 .

Practical Synthesis of Chiral Synthons for the Preparation of HMG-CoA Reductase Inhibitors

T. Konoike, Y. Araki, 1994 .

Photoinduced reactions. LXII. Photochemical reaction of α-nitroepoxides

I. Saito, T. Matsuura, T. Konoike, 1972 .

π-Facial Selection in Intermolecular Diels-Alder Reactions: Total Syntheses of (+)-Actinobolin and (+)-5,6,10-triepi-Actinobolin.

J. Springer, A. Kozikowski, T. Konoike, 1987 .

A Total Synthesis of Actinobolin via the Intermolecular Diels-Alder Reaction of a Threonine Derived Diene.

A. Kozikowski, T. Konoike, T. Nieduzak, 1987 .

Electron transfer from copper-isonitrile complex producing radical anion

T. Saegusa, T. Konoike, Y. Ito, 1974 .

Concise allene synthesis from propargylic alcohols by hydrostannation and deoxystannylation: A new route to chiral allenes

T. Konoike, Y. Araki, 1992 .

Oxidative Coupling of Carbon Acid Compounds by Means of Ag2O

T. Saegusa, T. Konoike, Y. Ito, 1976 .

Total synthesis of human chymase inhibitor methyllinderone and structure--activity relationships of its derivatives.

Y. Aoyama, N. Naya, M. Nakajima, 2001, Bioorganic & medicinal chemistry letters.

SYNTHESIS OF 2-13C-OLEANOLIC ACID AND 2-13C-MYRICERONE

T. Konoike, Y. Kanda, Kazuhiro Takahashi, 1999 .

Process Development of HIV Integrase Inhibitor S‐1360

T. Konoike, S. Shimizu, S. Shimizu, 2010 .

(S)-(−)-2-tert-butyl-3-methylene-oxirane: Synthesis and hydroboration of a chiral allene oxide

Tetsuyoshi Hayashi, T. Konoike, Y. Araki, 1994 .

A new route to cumulenes by stannylation-deoxystannylation of propargylic alcohols. Application to synthesis of conjugated enyne[3]cumulene as a model compound of neocarzinostatin chromophore

T. Konoike, Y. Araki, 1998 .

1-Oxacephem-based human chymase inhibitors: discovery of stable inhibitors in human plasma.

Y. Aoyama, N. Naya, M. Nakajima, 2000, Bioorganic & medicinal chemistry letters.

A novel allylic hydroxylation of sterically hindered olefins by Fe-porphyrin-catalyzed mCPBA oxidation

T. Konoike, Y. Kanda, Y. Araki, 1999 .

Practical Partial Synthesis of Myriceric Acid A, an Endothelin Receptor Antagonist, from Oleanolic Acid

I. Horibe, T. Konoike, Y. Araki, 1997 .

Synthesis and structure-activity relationships of potent and orally active sulfonamide ETB selective antagonists.

M. Ninomiya, T. Kanemasa, K. Asakura, 2001, Bioorganic & medicinal chemistry.

Practical procedure for epimerization of 7α-amino-1-oxacephems to 7β-amino epimers

W. Nagata, N. Haga, T. Konoike, 1985 .

TREATMENT OF CANCER AND NFLAMMLATORY DISEASEBY INHIBITION OF NF-kB

Kazuhiro Takahashi, Tomohiro Sato, K. Liby, 2017 .

Discovery and synthesis of a potent sulfonamide ET(B) selective antagonist.

M. Fujimoto, S. Mihara, T. Konoike, 2000, Bioorganic & medicinal chemistry letters.

Endothelin receptor antagonist triterpenoid, myriceric acid A, isolated from Myrica cerifera, and structure activity relationships of its derivatives.

T. Iwata, M. Fujimoto, Y. Terui, 1996, Chemical & pharmaceutical bulletin.