E. Boros

发表

Discovery of a highly potent, nonabsorbable apical sodium-dependent bile acid transporter inhibitor (GSK2330672) for treatment of type 2 diabetes.

M. J. Bishop, J. Ambroso, J. Collins, 2013, Journal of medicinal chemistry.

Inhibition of Tumor Necrosis Factor-induced Cell Death in MCF7 by a Novel Inhibitor of Neutral Sphingomyelinase*

Y. Hannun, L. Obeid, Y. Okamoto, 2002, The Journal of Biological Chemistry.

Preparation of fluorinated phenoxathiin dioxide monoamine oxidase‐A inhibitors: Intramolecular radical substitution at sulfur versus the mauthner synthesis

M. Harfenist, W. Hall, J. Kelley, 1998 .

Discovery of 4-Amino-8-quinoline Carboxamides as Novel, Submicromolar Inhibitors of NAD-Hydrolyzing Enzyme CD38.

J. D. Stuart, L. Shewchuk, B. Shearer, 2015, Journal of medicinal chemistry.

A Scaleable Synthesis of Methyl 3-Amino-5-(4-fluorobenzyl)-2-pyridinecarboxylate

S. A. Burova, M. Sharp, C. Koble, 2007 .

Synthesis of ultra-short-acting neuromuscular blocker GW 0430: a remarkably stereo- and regioselective synthesis of mixed tetrahydroisoquinolinium chlorofumarates.

J. A. Ray, R. Mook, V. Samano, 1999, Organic letters.

Enzymatic- and iridium-catalyzed asymmetric synthesis of a benzothiazepinylphosphonate bile acid transporter inhibitor.

J. A. Ray, Amy A Sarjeant, J. Collins, 2013, The Journal of organic chemistry.

A scalable Nenitzescu synthesis of 2‐methyl‐4‐(trifluoromethyl)‐1H‐indole‐5‐carbonitrile

I. Kaldor, P. Turnbull, E. Boros, 2011 .

A new route to N-monosubstituted thioamides utilizing phosphoramidothionates as reagents for the thioamidation of carboxylic acids

E. Boros, K. E. Debruin, 1990 .

New diol metabolites derived by biooxidation of chlorostyrenes with Pseudomonas putida : determination of absolute stereochemistry and enantiomeric excess by convergent syntheses

T. Hudlický, C. Boros, E. Boros, 1993 .

Palladium-catalyzed coupling of terminal alkynes to the free cis-diol metabolite produced from the oxidation of bromobenzene by pseudomonas putida: Synthesis of new homochiral 3-alkynyl cis-cyclohexa-3,5-diene-1,2-diols

T. Hudlický, E. Boros, 1992 .

Stereoselective dimerizations of arene-cis-diol acetonides derived from the oxidation of halobenzenes by Pseudomonas putida: absolute configuration of the adducts by x-ray crystallography

T. Hudlický, H. Olivo, E. Boros, 1992 .

Stereocontrolled synthesis of cis-dibenzoquinolizine chlorofumarates: curare-like agents of ultrashort duration.

J. A. Ray, R. Mook, A. Sefler, 2001, The Journal of organic chemistry.

Discovery, Synthesis, and Biological Evaluation of Thiazoloquin(az)olin(on)es as Potent CD38 Inhibitors.

J. D. Stuart, W. Harrington, B. Henke, 2015, Journal of medicinal chemistry.

Synthesis and antiviral activity of 7-benzyl-4-hydroxy-1,5-naphthyridin-2(1H)-one HIV integrase inhibitors.

E. Garvey, S. Foster, T. Fujiwara, 2009, Journal of medicinal chemistry.

Degenerate Racemization of Chiral Saddle Conformations in a Cyclic Dioxadithia Aryl Polyether

E. Boros, A. O. Davis, A. W. Andrews, 1996 .

Synthesis and HIV-integrase strand transfer inhibition activity of 7-hydroxy[1,3]thiazolo[5,4-b]pyridin-5(4H)-ones.

E. Garvey, C. Koble, W. H. Miller, 2006, Bioorganic & medicinal chemistry letters.

Naphthyridinone (NTD) integrase inhibitors 4. Investigating N1 acetamide substituent effects with C3 amide groups.

E. Garvey, S. Foster, T. Fujiwara, 2014, Bioorganic & medicinal chemistry letters.

Naphthyridinone (NTD) integrase inhibitors: N1 protio and methyl combination substituent effects with C3 amide groups.

E. Garvey, S. Foster, T. Fujiwara, 2013, Bioorganic & medicinal chemistry letters.

Combining symmetry elements results in potent naphthyridinone (NTD) HIV-1 integrase inhibitors.

E. Garvey, S. Foster, T. Fujiwara, 2011, Bioorganic & medicinal chemistry letters.

The Naphthyridinone GSK364735 Is a Novel, Potent Human Immunodeficiency Virus Type 1 Integrase Inhibitor and Antiretroviral

E. Garvey, S. Foster, T. Fujiwara, 2007, Antimicrobial Agents and Chemotherapy.

Tandem Michael‐addition/cyclization synthesis and EGFR kinase inhibition activity of pyrido[2,3‐d]pyrimidin‐7(8H)‐ones

A. Sefler, T. Spitzer, E. Wood, 2004 .

A pre-steady state and steady state kinetic analysis of the N-ribosyl hydrolase activity of hCD157.

L. Shewchuk, E. Stewart, D. J. Porter, 2014, Archives of biochemistry and biophysics.

Preclinical Pharmacology of GW280430A (AV430A) in the Rhesus Monkey and in the Cat: A Comparison with Mivacurium

Sanjay S. Patel, R. Mook, T. Spitzer, 2004, Anesthesiology.

Neuromuscular blocking activity and therapeutic potential of mixed-tetrahydroisoquinolinium halofumarates and halosuccinates in rhesus monkeys.

Sanjay S. Patel, J. A. Ray, R. Mook, 2003, Journal of medicinal chemistry.

Bis- and mixed-tetrahydroisoquinolinium chlorofumarates: new ultra-short-acting nondepolarizing neuromuscular blockers.

J. A. Ray, R. Mook, V. Samano, 1999, Journal of medicinal chemistry.

A convenient synthesis of pyrazolidine and 3‐amino‐6,7‐dihydro‐1H,5H‐pyrazolo[1,2‐a] pyrazol‐1‐one

F. Bouvier, E. Boros, M. Rabinowitz, 2001 .

Alkali Carbonate Effects on N‐(2‐Hydroxyethyl)urea Cyclization: Application to a 2‐Imidazolidinone Scale‐Up

W. Kazmierski, T. Spitzer, I. Kaldor, 2013 .

Discovery of 6,7-dihydro-5H-pyrrolo[2,3-a]pyrimidines as orally available G protein-coupled receptor 119 agonists.

S. Roller, J. Way, S. Ross, 2012, Journal of medicinal chemistry.

A Model Study Directed Towards a Practical Enantioselective Total Synthesis of (-)-Morphine

T. Hudlický, C. Boros, E. Boros, 1992 .

Synthesis of 4‐Substituted Piperidines via a Mild and Scalable Two‐Step Cu2O‐Mediated Decarboxylation of Cyanoesters

W. Kazmierski, B. Chauder, C. Koble, 2006 .

Synthesis of 4-Substituted Piperidines via a Mild and Scalable Two-Step Cu2O-Mediated Decarboxylation of Cyanoesters.

W. Kazmierski, B. Chauder, C. Koble, 2006 .

Facile reductive amination of aldehydes with electron-deficient anilines by acyloxyborohydrides in TFA: application to a diazaindoline scale-up.

A. Carpenter, S. R. Katamreddy, E. Boros, 2009, The Journal of organic chemistry.

Thermal Synthesis of 3‐Bromothieno[3,2‐c]pyridin‐4‐(5H)‐one: A Telescoped Procedure with Tributylamine

I. Kaldor, E. Boros, 2015 .

Discovery of a highly potent, nonabsorbable apical sodium-dependent bile acid transporter inhibitor (GSK2330672) for treatment of type 2 diabetes.

M. J. Bishop, J. Ambroso, J. Collins, 2013, Journal of medicinal chemistry.