Malcolm P. Huestis

发表

Photoredox/Nickel Dual Catalytic Cross-Coupling of Potassium Thiomethyltrifluoroborates with Aryl and Heteroaryl Bromides.

J. Tellis, Katherine M. Townsend, Malcolm P. Huestis, 2021, The Journal of organic chemistry.

Intramolecular Pd(II)-catalyzed oxidative biaryl synthesis under air: reaction development and scope.

David R. Stuart, K. Fagnou, Benoît Liégault, 2008, The Journal of organic chemistry.

AB3 building blocks for the synthesis of polyester dendrimers

T. Grindley, Jean-d’Amour K. Twibanire, Malcolm P. Huestis, 2014 .

Lipophilic sugar nucleotide synthesis by structure-based design of nucleotidylyltransferase substrates.

E. C. Soo, J. Hui, D. Jakeman, 2008, Organic & biomolecular chemistry.

Enzyme-catalyzed synthesis of isosteric phosphono-analogues of sugar nucleotides.

N. R. Thomas, D. Jakeman, A. Sadeghi-Khomami, 2009, Chemical communications.

Design and Evaluation of Highly-Selective Human Immunoproteasome Inhibitors Reveals a Compensatory Process that Preserves Immune Cell Viability.

S. Steinbacher, M. Augustin, Celine Eidenschenk, 2019, Journal of medicinal chemistry.

Site-selective azaindole arylation at the azine and azole rings via N-oxide activation.

K. Fagnou, Malcolm P. Huestis, 2009, Organic letters.

Cp*Rh(III)‐Catalyzed C8 C−H Alkylation of Quinoline N ‐Oxides with Diazo Meldrum's Acid

Samuel Aubert‐Nicol, R. Larouche‐Gauthier, Jean-Philippe Leclerc, 2021 .

The vinyl moiety as a handle for regiocontrol in the preparation of unsymmetrical 2,3-aliphatic-substituted indoles and pyrroles.

David R. Stuart, K. Fagnou, Malcolm P. Huestis, 2011, Angewandte Chemie.

Intramolecular Pd(II)‐Catalyzed Oxidative Biaryl Synthesis under Air: Reaction Development and Scope.

David R. Stuart, K. Fagnou, Benoît Liégault, 2008 .

Site‐Selective Azaindole Arylation at the Azine and Azole Rings via N‐Oxide Activation.

K. Fagnou, Malcolm P. Huestis, 2009 .

Dual Photoredox/Nickel-Catalyzed Conversion of Aryl Halides to Aryl Aminooxetanes: Computational Evidence for a Substrate-Dependent Switch in Mechanism

J. Grandner, Ryan Khalaf, Yongsheng Chen, 2020, ACS Catalysis.

Rhodium(III)-Catalyzed C-H Functionalization of 1-(2H)-Phthalazinones at C8.

Malcolm P. Huestis, 2016, The Journal of organic chemistry.

Directed Cp*RhIII-Catalyzed Fluorosulfonylvinylation of Arenes

Malcolm P. Huestis, Gqwetha Ncube, 2018, Organometallics.

Iridium(III)‐Catalyzed Benzylic Amine Directed CH Sulfonamidation of Arenes with Sulfonyl Azides

Heng Chen, Malcolm P. Huestis, 2015 .

Iridium(III)‐Catalyzed Benzylic Amine Directed C—H Sulfonamidation of Arenes with Sulfonyl Azides.

Heng Chen, Malcolm P. Huestis, 2015 .

Cyanide anion as a leaving group in nucleophilic aromatic substitution: synthesis of quaternary centers at azine heterocycles.

Malcolm P. Huestis, Alexander D Thompson, 2013, The Journal of organic chemistry.

The Vinyl Moiety as a Handle for Regiocontrol in the Preparation of Unsymmetrical 2,3‐Aliphatic‐Substituted Indoles and Pyrroles.

David R. Stuart, K. Fagnou, Malcolm P. Huestis, 2011 .

Targeting KRAS Mutant Cancers via Combination Treatment: Discovery of a 5-Fluoro-4-(3H)-quinazolinone Aryl Urea pan-RAF Kinase Inhibitor.

C. Eigenbrot, Ivana Yen, S. Malek, 2021, Journal of medicinal chemistry.

Sequential C3 and C5 Direct C–H Arylation of Imidazo[1,2‐a]pyrazines with (Hetero)aryl Bromides

Malcolm P. Huestis, B. M. Johnson, 2014 .

Sequential C3 and C5 Direct C—H Arylation of Imidazo[1,2-a]pyrazines with (Hetero)aryl Bromides.

Malcolm P. Huestis, B. M. Johnson, 2015 .

Synthesis, characterization, and PK/PD studies of a series of spirocyclic pyranochromene BACE1 inhibitors.

M. Volgraf, G. Vigers, Xingrong Liu, 2014, Bioorganic & medicinal chemistry letters.

Discovery of dual leucine zipper kinase (DLK, MAP3K12) inhibitors with activity in neurodegeneration models.

K. Scearce-Levie, K. Stark, C. Ly, 2015, Journal of medicinal chemistry.

Ni-Catalyzed Reductive Cross-Coupling of Cyclopropylamines and Other Strained Ring NHP Esters with (Hetero)Aryl Halides.

Sophie A. L. Rousseaux, Malcolm P. Huestis, Michael S West, 2022, Organic letters.

Diethylaminosulfur trifluoride-mediated intramolecular cyclization of 2-hydroxycycloalkylureas to fused bicyclic aminooxazoline compounds and evaluation of their biochemical activity against β-secretase-1 (BACE-1)

G. Vigers, Darin J. Smith, Weiru Wang, 2013 .

Targeting KRAS Mutant Cancers via Combination Treatment: Discovery of a Pyridopyridazinone pan-RAF Kinase Inhibitor.

C. Eigenbrot, Ivana Yen, S. Malek, 2021, ACS medicinal chemistry letters.

Engineering ribonucleoside triphosphate specificity in a thymidylyltransferase.

V. Ferrières, D. Jakeman, R. Daniellou, 2008, Biochemistry.

The vinyl moiety as a handle for regiocontrol in the preparation of unsymmetrical 2,3-aliphatic-substituted indoles and pyrroles.

David R. Stuart, K. Fagnou, Malcolm P. Huestis, 2011, Angewandte Chemie.