M. D. Kaytor

发表

Comparative proteomic analysis of serum from nonhuman primates administered BIO 300: a promising radiation countermeasure

A. Cheema, V. Singh, Yaoxiang Li, 2020, Scientific reports.

Pharmacokinetic and Metabolomic Studies with BIO 300, a Nanosuspension of Genistein, in a Nonhuman Primate Model

Khyati Y Mehta, A. Cheema, V. Singh, 2019, International journal of molecular sciences.

Targeted Metabolomics Identifies Pharmacodynamic Biomarkers for BIO 300 Mitigation of Radiation-Induced Lung Injury

Jace W. Jones, M. Kane, Ž. Vujašković, 2017, Pharmaceutical Research.

Allele-specific suppression of temperature-sensitive mutations of theSaccharomyces cerevisiae RAD52 gene

D. M. Livingston, M. D. Kaytor, 1996, Current Genetics.

Safety, Pharmacokinetics, and Biomarkers of an Amorphous Solid Dispersion of Genistein, a Radioprotectant, in Healthy Volunteers

Carin Verduyn, Artur A. Serebrenik, M. D. Kaytor, 2022, Clinical pharmacology in drug development.

BIO 300, a nanosuspension of genistein, mitigates pneumonitis/fibrosis following high‐dose radiation exposure in the C57L/J murine model

M. Kuskowski, R. Pavlović, Ž. Vujašković, 2017, British journal of pharmacology.

Pharmacokinetic and metabolomic studies with a BIO 300 Oral Powder formulation in nonhuman primates

A. Cheema, Yaoxiang Li, Michael Girgis, 2022, Scientific Reports.

Peptide- polynucleotide compositions for transfecting a cell with dna and for treating a neurodegenerative disease

W. Kaemmerer, Marcy R Weatherspoon, Julie A. Alkatout, 2010 .

Ataxin-1 Nuclear Localization and Aggregation Role in Polyglutamine-Induced Disease in SCA1 Transgenic Mice

Harry T Orr, Pamela J Skinner, Steven M Hersch, 1998, Cell.

Novel Vector Design and Hexosaminidase Variant Enabling Self-Complementary Adeno-Associated Virus for the Treatment of Tay-Sachs Disease.

P. Thompson, S. Gray, M. Kaytor, 2016, Human gene therapy.

A cell-based screen for modulators of ataxin-1 phosphorylation.

Harry T Orr, H. Zoghbi, H. Orr, 2005, Human molecular genetics.

CHAPTER K3 – Animal Models of Spinocerebellar Ataxia Type 1 (SCA1)

H. Orr, M. D. Kaytor, 2005 .

Interaction of Akt-Phosphorylated Ataxin-1 with 14-3-3 Mediates Neurodegeneration in Spinocerebellar Ataxia Type 1

H. Zoghbi, J. Botas, H. Orr, 2003, Cell.

Serine 776 of Ataxin-1 Is Critical for Polyglutamine-Induced Disease in SCA1 Transgenic Mice

Effat S. Emamian, Huda Y. Zoghbi, Harry T. Orr, 2003, Neuron.

Interspecies Comparison and Radiation Effect on Pharmacokinetics of BIO 300, a Nanosuspension of Genistein, after Different Routes of Administration in Mice and Non-Human Primates

J. Gobburu, Ž. Vujašković, M. Kaytor, 2022, Radiation Research.

Nuclear localization of the spinocerebellar ataxia type 7 protein, ataxin-7.

H. Orr, L. Ranum, L. Duvick, 1999, Human molecular genetics.

Saccharomyces cerevisiae RAD52 alleles temperature-sensitive for the repair of DNA double-strand breaks.

M. Kaytor, D. M. Livingston, M. D. Kaytor, 1994, Genetics.

Mechanism and therapeutic window of a genistein nanosuspension to protect against hematopoietic-acute radiation syndrome.

R. Day, M. Landauer, Adam J Harvey, 2019, Journal of radiation research.

Modulating huntingtin half‐life alters polyglutamine‐dependent aggregate formation and cell toxicity

K. Wilkinson, M. D. Kaytor, S. T. Warren, 2004, Journal of neurochemistry.

GSG1, a yeast gene required for sporulation

D. M. Livingston, M. D. Kaytor, 1995, Yeast.

A novel oral formulation of BIO 300 confers prophylactic radioprotection from acute radiation syndrome in mice

V. Singh, M. Kaytor, Stephen Y Wise, 2021, International journal of radiation biology.

Pharmacokinetic and metabolomic studies with a BIO 300 Oral Powder formulation in nonhuman primates

A. Cheema, Yaoxiang Li, Michael Girgis, 2022, Scientific Reports.

A C57L/J Mouse Model of the Delayed Effects of Acute Radiation Exposure in the Context of Evolving Multi-Organ Dysfunction and Failure after Total-Body Irradiation with 2.5% Bone Marrow Sparing

M. Gopalakrishnan, J. Down, A. Zodda, 2023, Radiation Research.

Recovery from Polyglutamine-Induced Neurodegeneration in Conditional SCA1 Transgenic Mice

Harry T Orr, Tao Zu, H. Zoghbi, 2004, The Journal of Neuroscience.

Increased trinucleotide repeat instability with advanced maternal age.

H. Zoghbi, H. Orr, E. Burright, 1997, Human molecular genetics.

The GSK3β signaling cascade and neurodegenerative disease

H. Orr, M. D. Kaytor, 2002, Current Opinion in Neurobiology.

Microbiome study in irradiated mice treated with BIO 300, a promising radiation countermeasure

A. Cheema, V. Singh, Ryan C. Johnson, 2021, Animal microbiome.

BIO 300, a nanosuspension of genistein, mitigates radiation-induced erectile dysfunction and sensitizes human prostate cancer xenografts to radiation therapy.

R. Pavlović, Ž. Vujašković, J. Eley, 2019, International journal of radiation oncology, biology, physics.

Aberrant Protein Deposition and Neurological Disease*

S. Warren, M D Kaytor, S T Warren, 1999, The Journal of Biological Chemistry.

The GSK3 beta signaling cascade and neurodegenerative disease.

H. Orr, M. D. Kaytor, 2002, Current opinion in neurobiology.

Six-month partial suppression of Huntingtin is well tolerated in the adult rhesus striatum

P. Nelson, D. Thakker, Zhiming Zhang, 2012, Brain : a journal of neurology.

DNA Nanoparticles: Detection of Long-Term Transgene Activity in Brain using Bioluminescence Imaging

M. McShane, T. Kowalczyk, M. Cooper, 2011, Molecular imaging.

The Complexity of the Interaction Between RAD 52 and SRs 2

D. M. Livingston, D. Michael, M. D. Kaytor, 2022 .

RNA Targets of the Fragile X Protein

H. Orr, M. D. Kaytor, 2001, Cell.

The Radioprotectant, BIO 300, Protects the Lungs from Total-Body Irradiation Injury in C57L/J Mice

Artur A. Serebrenik, M. D. Kaytor, Oluseyi O. Fatanmi, 2023, Radiation Research.