M. Beard

发表

In addition to the SH3 binding region, multiple regions within the N-terminal noncatalytic portion of the cAMP-specific phosphodiesterase, PDE4A5, contribute to its intracellular targeting.

M. Houslay, E. Huston, I. Gall, 2002, Cellular signalling.

Intracellular compartmentalization of PDE4 cyclic AMP-specific phosphodiesterases.

M. Houslay, S. Mackenzie, E. Huston, 1998, Methods.

The unique N‐terminal domain of the cAMP phosphodiesterase PDE4D4 allows for interaction with specific SH3 domains

M. Houslay, G. Bolger, M. Beard, 1999, FEBS letters.

Long PDE4 cAMP specific phosphodiesterases are activated by protein kinase A‐mediated phosphorylation of a single serine residue in Upstream Conserved Region 1 (UCR1)

Ian McPhee, G. Baillie, M. Houslay, 2002, British journal of pharmacology.

UCR1 and UCR2 Domains Unique to the cAMP-specific Phosphodiesterase Family Form a Discrete Module via Electrostatic Interactions*

M. Houslay, G. Bolger, Aileen E. Olsen, 2000, The Journal of Biological Chemistry.

Association with the SRC Family Tyrosyl Kinase LYN Triggers a Conformational Change in the Catalytic Region of Human cAMP-specific Phosphodiesterase HSPDE4A4B

M. Houslay, E. Huston, S. Yarwood, 1999, The Journal of Biological Chemistry.

Sequential tethering of Golgins and catalysis of SNAREpin assembly by the vesicle-tethering protein p115

G. Warren, J. Shorter, J. Seemann, 2002, The Journal of cell biology.

Golgin‐84 is a rab1 Binding Partner Involved in Golgi Structure

G. Warren, J. Malsam, Yanzhuang Wang, 2003, Traffic.

Intracellular targeting, interaction with Src homology 3 (SH3) domains and rolipram-detected conformational switches in cAMP-specific PDE4A phosphodiesterase.

M. Houslay, G. Rena, S. Mackenzie, 1997, Biochemical Society transactions.

The cAMP-specific phosphodiesterase PDE4A5 is cleaved downstream of its SH3 interaction domain by caspase-3. Consequences for altered intracellular distribution.

P. Vandenabeele, M. Houslay, N. Pyne, 2000, The Journal of biological chemistry.

Sequential tethering of Golgins and catalysis of SNAREpin assembly by the vesicle-tethering protein p115

G. Warren, J. Shorter, J. Seemann, 2002, The Journal of cell biology.