Josefine Striepen

发表

Mechanisms of APOBEC3 mutagenesis in human cancer cells

Erik N. Bergstrom, M. Stratton, L. Alexandrov, 2022, Nature.

Repositioning and Characterization of 1-(Pyridin-4-yl)pyrrolidin-2-one Derivatives as Plasmodium Cytoplasmic Prolyl-tRNA Synthetase Inhibitors

David M. Shackleford, D. Fidock, Laura M Sanz, 2021, ACS infectious diseases.

Novel Antimalarial Tetrazoles and Amides Active against the Hemoglobin Degradation Pathway in Plasmodium falciparum.

E. Winzeler, D. Fidock, M. Phillips, 2021, Journal of medicinal chemistry.

Discovery and Characterization of Potent, Efficacious, Orally Available Antimalarial Plasmepsin X Inhibitors and Preclinical Safety Assessment of UCB7362

Richard D. Taylor, D. Goldberg, A. Cowman, 2022, Journal of medicinal chemistry.

Chemogenomics identifies acetyl-coenzyme A synthetase as a target for malaria treatment and prevention

E. Winzeler, I. Gilbert, M. Llinás, 2021, Cell chemical biology.

P. falciparum K13 mutations present varying degrees of artemisinin resistance and reduced fitness in African parasites

P. Rosenthal, D. Fidock, L. Ross, 2021, bioRxiv.

Plasmodium falciparum K13 mutations in Africa and Asia impact artemisinin resistance and parasite fitness

D. Fidock, L. Ross, F. Nosten, 2021, eLife.

Plasmodium falciparum K13 mutations in Africa and Asia present varying degrees of artemisinin resistance and an elevated fitness cost in African parasites

P. Rosenthal, D. Fidock, L. Ross, 2021, bioRxiv.

Preclinical characterization and target validation of the antimalarial pantothenamide MMV693183

P. Rosenthal, M. Llinás, D. Fidock, 2021, bioRxiv.

Potent Antimalarials with Development Potential Identified by Structure-Guided Computational Optimization of a Pyrrole-Based Dihydroorotate Dehydrogenase Inhibitor Series.

David M. Shackleford, E. Winzeler, P. Rathod, 2021, Journal of medicinal chemistry.

Propensity of selecting mutant parasites for the antimalarial drug cabamiquine

D. Fidock, D. Khoury, A. Djimde, 2023, Nature Communications.

APOBEC Mutagenesis in Cancer Development and Susceptibility

Alexandra Dananberg, Josefine Striepen, Jacob S. Rozowsky, 2024, Cancers.

Discovery and Characterization of Potent, Efficacious, Orally Available Antimalarial Plasmepsin X Inhibitors and Preclinical Safety Assessment of UCB7362

Richard D. Taylor, D. Goldberg, A. Cowman, 2022, Journal of medicinal chemistry.