G. Pasquet

发表

Discovery, synthesis, and in vivo activity of a new class of pyrazoloquinazolines as selective inhibitors of aurora B kinase.

N. Keen, S. Wedge, S. Heaton, 2007, Journal of medicinal chemistry.

Discovery of new quinoline ether inhibitors with high affinity and selectivity for PDGFR tyrosine kinases.

S. Ashton, R. Morgentin, P. Plé, 2012, Bioorganic & medicinal chemistry letters.

Discovery of AZD2932, a new Quinazoline Ether Inhibitor with high affinity for VEGFR-2 and PDGFR tyrosine kinases.

S. Ashton, R. Morgentin, P. Plé, 2012, Bioorganic & medicinal chemistry letters.

Synthesis and SAR of 1-acetanilide-4-aminopyrazole-substituted quinazolines: selective inhibitors of Aurora B kinase with potent anti-tumor activity.

N. Keen, S. Wedge, S. Heaton, 2008, Bioorganic & Medicinal Chemistry Letters.

A versatile route to 3-(pyrimidin-4-yl)-imidazo[1,2-a]pyridines and 3-(pyrimidin-4-yl)-pyrazolo[1,5-a]pyridines

G. L. Young, R. Ducray, M. Maudet, 2010 .

Strategic studies in the syntheses of novel 6,7-substituted quinolones and 7-or 6-substituted 1,6-and 1,7-naphthyridones

M. Maudet, R. Morgentin, P. Plé, 2008 .

An efficient large-scale synthesis of alkyl 5-hydroxy-pyridin- and pyrimidin-2-yl acetate

M. Maudet, R. Morgentin, P. Plé, 2009 .

Discovery of novel and potent thiazoloquinazolines as selective Aurora A and B kinase inhibitors.

Rajesh Odedra, Stephen Green, Nicola Heron, 2006, Journal of medicinal chemistry.

SYNTHESIS OF (.+-.)-NEGAMYCIN AND OF (.+-.)-EPINEGAMYCIN

B. J. Wright, W. Pilgrim, G. Pasquet, 1980 .

Discovery of 1-(4-(5-(5-amino-6-(5-tert-butyl-1,3,4-oxadiazol-2-yl)pyrazin-2-yl)-1-ethyl-1,2,4-triazol-3-yl)piperidin-1-yl)-3-hydroxypropan-1-one (AZD8835): A potent and selective inhibitor of PI3Kα and PI3Kδ for the treatment of cancers.

S. Green, Rebecca P A Ellston, B. Barlaam, 2015, Bioorganic & medicinal chemistry letters.

Abstract 2830: Discovery of AZD8835, a potent and selective inhibitor of PI3Kα and PI3Kδ for the treatment ofPIK3CA-dependent cancers

S. Green, R. Morgentin, S. Cosulich, 2015 .

Facile preparation of thiophene C2-ethers using the Mitsunobu reaction

C. Harris, G. Pasquet, Hervé Germain, 2008 .

Strategic Studies in the Syntheses of Novel 6,7‐Substituted Quinolones and 7‐ or 6‐Substituted 1,6‐ and 1,7‐Naphthyridones.

M. Maudet, R. Morgentin, P. Plé, 2008 .