Dan Li

发表

Discovery of a highly selective JAK3 inhibitor for the treatment of rheumatoid arthritis

Sheng-yong Yang, Mingli Xiang, Zhuang Yang, 2018, Scientific Reports.

Anti-arthritis effect of a novel quinazoline derivative through inhibiting production of TNF-α mediated by TNF-α converting enzyme in murine collagen-induced arthritis model.

Ming-hai Tang, Heying Pei, Lijuan Chen, 2015, Biochemical and biophysical research communications.

SKLB060 Reversibly Binds to Colchicine Site of Tubulin and Possesses Efficacy in Multidrug-Resistant Cell Lines

Yiguo Hu, Sheng-yong Yang, Peng Bai, 2018, Cellular Physiology and Biochemistry.

The compound millepachine and its derivatives inhibit tubulin polymerization by irreversibly binding to the colchicine-binding site in β-tubulin

T. Yang, F. Wang, Heying Pei, 2018, The Journal of Biological Chemistry.

Discovery and synthesis of novel magnolol derivatives with potent anticancer activity in non-small cell lung cancer.

Ming-hai Tang, Lijuan Chen, Huan Tang, 2018, European journal of medicinal chemistry.

Therapeutic efficacy of an injectable formulation of purinostat mesylate in SU-DHL-6 tumour model

Zhuang Yang, Ming-hai Tang, Heying Pei, 2022, Annals of medicine.

Discovery, Optimization, and Evaluation of Potent and Selective PI3Kδ-γ Dual Inhibitors for the Treatment of B-cell Malignancies.

T. Yang, Yong Guo, Ming-hai Tang, 2022, Journal of medicinal chemistry.

TAK1 inhibition by natural cyclopeptide RA-V promotes apoptosis and inhibits protective autophagy in Kras-dependent non-small-cell lung carcinoma cells

F. Wang, Zhe Wang, Yingjie Guo, 2018, RSC advances.

Design, synthesis and biological evaluation of 7H-pyrrolo[2,3-d]pyrimidin-4-amine derivatives as selective Btk inhibitors with improved pharmacokinetic properties for the treatment of rheumatoid arthritis.

Mingli Xiang, Heying Pei, Lijuan Chen, 2018, European journal of medicinal chemistry.

Discovery, Optimization, and Evaluation of Quinazolinone Derivatives with Novel Linkers as Orally Efficacious Phosphoinositide-3-Kinase Delta Inhibitors for Treatment of Inflammatory Diseases.

Zhuang Yang, Ming-hai Tang, Lijuan Chen, 2021, Journal of medicinal chemistry.

Design, synthesis and biological evaluation of 4-anilinoquinoline derivatives as novel potent tubulin depolymerization agents.

M. Shen, F. Wang, Zhuang Yang, 2017, European journal of medicinal chemistry.

Design, Synthesis, and Bioactivity Evaluation of Dual-Target Inhibitors of Tubulin and Src Kinase Guided by Crystal Structure.

Ming-hai Tang, Lijuan Chen, Wei-Qun Yan, 2021, Journal of medicinal chemistry.

SKLB-23bb, A HDAC6-Selective Inhibitor, Exhibits Superior and Broad-Spectrum Antitumor Activity via Additionally Targeting Microtubules

Yuquan Wei, Yiguo Hu, F. Wang, 2018, Molecular Cancer Therapeutics.

SKLB-14b, a novel oral microtubule-destabilizing agent based on hydroxamic acid with potent anti-tumor and anti-multidrug resistance activities.

Zhuang Yang, Ming-hai Tang, Wanhua Zhang, 2022, Bioorganic chemistry.

Therapeutic potential of a synthetic FABP4 inhibitor 8g on atherosclerosis in ApoE-deficient mice: the inhibition of lipid accumulation and inflammation

Liang Ma, Heying Pei, Lijuan Chen, 2016 .

Discovery and synthesis of novel magnolol derivatives with potent anticancer activity in non-small cell lung cancer.

Ming-hai Tang, Lijuan Chen, Huan Tang, 2018, European journal of medicinal chemistry.

Discovery, Optimization, and Evaluation of Potent and Selective DNA-PK Inhibitors in Combination with Chemotherapy or Radiotherapy for the Treatment of Malignancies.

Zhuang Yang, Yong Chen, Dexin Deng, 2023, Journal of medicinal chemistry.