B. Zamlynny

发表

Discovery of novel non-steroidal reverse indole mineralocorticoid receptor antagonists.

J. Lisnock, A. Crespo, Gaochao Zhou, 2016, Bioorganic & medicinal chemistry letters.

Discovery of novel oxazolidinedione derivatives as potent and selective mineralocorticoid receptor antagonists.

J. Lisnock, A. Crespo, Gaochao Zhou, 2013, Bioorganic & medicinal chemistry letters.

Design, synthesis, and evaluation of conformationally restricted acetanilides as potent and selective β3 adrenergic receptor agonists for the treatment of overactive bladder.

M. Struthers, R. Berger, C. Moyes, 2014, Journal of medicinal chemistry.

Distinct TLRs Is Due to Use of Mycobacterium tuberculosis and Macrophages in Response to Disparity in IL-12 Release in Dendritic Cells

S. Hickman, Sihyug Jang, P. Salgame, 2007 .

Oxetane Promise Delivered: Discovery of Long-Acting IDO1 Inhibitors Suitable for Q3W Oral or Parenteral Dosing.

Theodore A. Martinot, Yongxin Han, N. Solban, 2022, Journal of medicinal chemistry.

Discovery of Vibegron: A Potent and Selective β3 Adrenergic Receptor Agonist for the Treatment of Overactive Bladder.

M. Struthers, R. Berger, C. Moyes, 2016, Journal of medicinal chemistry.

Development of indazole mineralocorticoid receptor antagonists and investigation into their selective late-stage functionalization.

K. Houk, J. Madwed, R. DeVita, 2019, Bioorganic & medicinal chemistry letters.

Structural insights on ligand recognition at the human leukotriene B4 receptor 1

V. Katritch, G. Han, V. Cherezov, 2021, Nature Communications.

Disparity in IL-12 Release in Dendritic Cells and Macrophages in Response to Mycobacterium tuberculosis Is Due to Use of Distinct TLRs1

S. Hickman, Sharada Ravikumar, Sihyug Jang, 2007, The Journal of Immunology.

Structures of active-state orexin receptor 2 rationalize peptide and small-molecule agonist recognition and receptor activation

M. Rudd, T. Mcdonald, S. Stachel, 2021, Nature Communications.

Discovery of benzimidazole oxazolidinediones as novel and selective nonsteroidal mineralocorticoid receptor antagonists.

J. Lisnock, A. Crespo, Gaochao Zhou, 2015, ACS medicinal chemistry letters.

Pharmacological Characterization of a Novel Beta 3 Adrenergic Agonist, Vibegron: Evaluation of Antimuscarinic Receptor Selectivity for Combination Therapy for Overactive Bladder

M. Struthers, J. Demartino, J. Woods, 2017, The Journal of Pharmacology and Experimental Therapeutics.

Structural Basis for Selectivity and Diversity in Angiotensin II Receptors

M. Rudd, R. Stevens, M. Hunter, 2017, Nature.

Potent targeted activator of cell kill molecules eliminate cells expressing HIV-1

Min Xu, D. Hazuda, M. Bukhtiyarova, 2023, Science Translational Medicine.

Mineralocorticoid receptor antagonists: identification of heterocyclic amide replacements in the oxazolidinedione series.

J. Lisnock, A. Crespo, Gaochao Zhou, 2014, Bioorganic & medicinal chemistry letters.