Y. Shealy

发表

N-(4-hydroxyphenyl)retinamide: interactions with retinoid-binding proteins/receptors.

D. Hill, B. Sani, Y. Shealy, 1995, Carcinogenesis.

Synthesis of D- and L-thalidomide and related studies.

J. Montgomery, Y. Shealy, C. E. Opliger, 1968, Journal of pharmaceutical sciences.

Complete Inhibition of Mouse Leukaemia L1210 by 5(or 4)-[3,3-Mbis (2-Chloroethyl)-l-triazeno]imidazole-4(or 5)-carboxamide (NSC-82196)

Y. Shealy, C. Krauth, C. A. Krauth, 1966, Nature.

Antitumor activity of triazenoimidazoles.

J. Montgomery, W. Laster, Y. Shealy, 1962, Biochemical pharmacology.

Retinyl methyl ether: binding to transport proteins and effect on transcriptional regulation.

D. Hill, B. Sani, X. Zhang, 1996, Biochemical and biophysical research communications.

Constituents of the Cotton Bud. XIII. Further Studies on a Nonpolar Feeding Stimulant for the Boll Weevil

P. Hedin, R. Struck, A. C. Thompson, 1968 .

Carbocyclic Analogues of 3′,4′-Didehydro-2′-deoxyribofuranosyl-2,4(1H,3H)-pyrimidinediones

Y. Shealy, C. O'dell, 1994 .

Synthesis and properties of the antileukemic agent 5(or 4)-[3,3-Bis(2-chloroethyl)-1-triazeno]imidazole-4(or 5)-carboxamide.

W. Fitzgibbon, Y. Shealy, C. A. Krauth, 1968, Journal of pharmaceutical sciences.

Triazeno-v-triazole-4-carboxamides. Synthesis and Antitumor Evaluation1,2

Y. Shealy, C. O'dell, 1966 .

Actinobolin. I. Basic degradation studies and the structure of a major degradation product.

W. C. Coburn, R. Struck, Martha C. Thorpe, 1967, Tetrahedron letters.

Synthesis of the carbocyclic analogs of uracil nucleosides

Y. Shealy, C. O'dell, 1976 .

Synthesis of Potential Anticancer Agents. XXIX. 5-Diazoimidazole-4-carboxamide and 5-Diazo-v-triazole-4-carboxamide1,2

J. Montgomery, R. Struck, Y. Shealy, 1961 .

v-Triazolo[4,5-d]pyrimidines. I. Synthesis and Nucleophilic Substitution of 7-Chloro Derivatives of 3-Substituted v-Triazolo[4,5-d]pyrimidines1

J. Montgomery, R. Struck, Y. Shealy, 1961 .

Effects of modifications in the pentose moiety and conformational changes on the binding of nucleoside ligands to uridine phosphorylase from Toxoplasma gondii.

R. Schinazi, C. K. Chu, S. Chu, 1996, Biochemical pharmacology.

Synthesis of carbocyclic analogs of purine ribonucleosides

Y. Shealy, J. D. Clayton, 1969 .

9-[β-DL-2α,3α-Dihydroxy-4β-(hydroxymethyl)- cyclopentyl]adenine, the Carbocyclic Analog of Adenosine1,2

Y. Shealy, J. D. Clayton, 1966 .

Potential folic acid antagonists. 5. Synthesis and biologic evaluation of N 10 -deazapteroic acid and N 10 -deazafolic acid and their 9,10-dehydro derivatives.

J. Montgomery, R. Struck, Y. Shealy, 1971, Journal of medicinal chemistry.

Resolution of racemic carbocyclic analogues of purine nucleosides through the action of adenosine deaminase. Antiviral activity of the carbocyclic 2'-deoxyguanosine enantiomers.

J. Montgomery, S. J. Clayton, J. Secrist, 1987, Journal of medicinal chemistry.

Some organoboron compounds containing a bis(2-chloroethyl)amino group joined to boron.

R. Struck, Y. Shealy, 1969, Journal of medicinal chemistry.

Intramolecular Diels-Alder reactions of the retinoid side chain

J. Riordan, Y. Shealy, J. Frye, 1996 .

Design of analogs of purine nucleosides with specifically altered activities as substrates for nucleoside- metabolizing enzymes.

R. W. Brockman, J. Montgomery, L. Bennett, 1977, Advances in enzyme regulation.

Thiadiazoles. I. Synthesis and Properties of [1,2,5]Thiadiazolo[3,4-d]pyrimidines1

J. Montgomery, Y. Shealy, J. D. Clayton, 1962 .

Synthesis and antiviral evaluation of carbocyclic analogues of 2-amino-6-substituted-purine 3'-deoxyribofuranosides.

G. Arnett, Y. Shealy, C. O'dell, 1987, Journal of medicinal chemistry.

1,2,5-selenadiazoles: a new class of highly cytotoxic compounds.

G. J. Dixon, R. Pittillo, E. A. Dulmadge, 1966, Biochemical pharmacology.

Imidazoles. I. Coupling Reactions of 5-Diazoimidazole-4-carboxamide1,2

J. Montgomery, Y. Shealy, C. A. Krauth, 1962 .

Constituents of the cotton bud. Mass spectrometric identification of the major high-molecular-weight hydrocarbons in buds and flowers

R. Struck, Y. Shealy, J. Frye, 1968 .

Reactions of diazo derivatives of 5-membered heterocycles with hydrazines

Y. Shealy, C. O'dell, 1973 .

Synthesis, antileukemic activity, and stability of 3-(substituted-triazeno)pyrazole-4-carboxylic acid esters and 3-(substituted-triazeno)pyrazole-4-carboxamides.

Y. Shealy, C. O'dell, 1971, Journal of pharmaceutical sciences.

Syntheses and biological activity of 5-aminoimidazoles and 5-triazenoimidazoles.

Y. Shealy, 1970, Journal of pharmaceutical sciences.

Imidazoles V. 5(or 4)-(3-alkyl-3-methyl-1-triazeno)imidazole-4(or 5)-carboxamides.

S. J. Clayton, A. Shortnacy, W. Laster, 1968, Journal of pharmaceutical sciences.

Synthesis of 3H‐labelled indicine N‐oxide

P. Kari, J. R. Piper, Y. Shealy, 1981 .

Nonenzymatic isomerization of 9-cis-retinoic acid catalyzed by sulfhydryl compounds.

T. Shih, D. Hill, T. H. Lin, 1997, Drug metabolism and disposition: the biological fate of chemicals.

Inhibition of Moloney murine lymphoma and sarcoma growth in vivo by dietary retinoids.

D. Dillehay, E. Lamon, Y. Shealy, 1989, Cancer research.

Biochemistry and Pharmacology of Retinoids in Relation to Chemoprevention of Cancer

T. Shih, D. Hill, Tsu-Han Lin, 1995 .

Synthesis and evaluation of some new retinoids for cancer chemoprevention.

Y F Shealy, Y. Shealy, 1989, Preventive medicine.

Carbocyclic analogs of anhydrothymidines: Carbocyclic Analogs of Anhydrothymidines

W. C. Coburn, Martha C. Thorpe, Y. Shealy, 1983 .

Carbocyclic analogs of anhydrothymidines

W. C. Coburn, Martha C. Thorpe, Y. Shealy, 1983 .

Retinoids and Differentiation of Cells of Mesenchymal Origin

M. Sporn, N. Roche, U. Heine, 1985 .

Amelioration of embryotoxicity by structural modification of the terminal group of cancer chemopreventive retinoids.

C. Willhite, Y. Shealy, 1984, Journal of the National Cancer Institute.

Acid-catalyzed cyclization of alkoxyacryloylureas to 2,4(1H,3H)pyrimidinediones

Y. Shealy, C. O'dell, 1976 .

Carbocyclic analogs of 2′-deoxyadenosine and 3′-deoxyadenosine

Y. Shealy, C. O'dell, 1969 .

Metabolism in Human Cells of the d and l Enantiomers of the Carbocyclic Analog of 2′-Deoxyguanosine: Substrate Activity with Deoxycytidine Kinase, Mitochondrial Deoxyguanosine Kinase, and 5′-Nucleotidase

G. Arnett, W. Mason, W. Parker, 1998, Antimicrobial Agents and Chemotherapy.

Carbocyclic analogs of thymine nucleosides and related 1-substituted thymines

Martha C. Thorpe, Y. Shealy, C. And, 1981 .

The carbocyclic analog of cytidine, synthesis and antineoplastic activity

Y. Shealy, C. O'dell, 1976 .

Carbocyclic analogues of 5-halocytosine nucleosides.

G. Arnett, W. C. Coburn, J. Riordan, 1986, Journal of medicinal chemistry.

Carbocyclic analog of cytarabine.

Y. Shealy, C. O'dell, 1979, Journal of pharmaceutical sciences.

Carbocyclic analogs of guanosine and 8-azaguanosine.

Y. Shealy, J. D. Clayton, 1973, Journal of pharmaceutical sciences.

Cyclopentyl derivatives of 8‐azahypoxanthine and 8‐azaadenine. Carbocyclic analogs of 8‐azainosine and 8‐azaadenosine

Y. Shealy, C. O'dell, J. D. Clayton, 1973 .

Carbocyclic analogs of 6-substituted purine ribonucleosides and of adenosine ribonucleotides.

Y. Shealy, J. D. Clayton, 1973, Journal of pharmaceutical sciences.

Carbocyclic analog of purine ribonucleosides with antileukemic activity.

Y. Shealy, J. D. Clayton, 1973, Journal of pharmaceutical sciences.

Phosphorylation of the carbocyclic analog of 2'-deoxyguanosine in cells infected with herpes viruses.

G. Arnett, L. Bennett, P. Allan, 1990, Biochemical pharmacology.

Effect of the N-glycosidic bond conformation and modifications in the pentose moiety on the binding of nucleoside ligands to uridine phosphorylase.

J. Imbach, S. Chu, S. Cha, 1988, Molecular pharmacology.

Evaluation of carbodine, the carbocyclic analog of cytidine, and related carbocyclic analogs of pyrimidine nucleosides for antiviral activity against human influenza Type A viruses

R. W. Brockman, G. Arnett, L. Westbrook, 1981, Antimicrobial Agents and Chemotherapy.

Broad-spectrum antiviral activity of carbodine, the carbocyclic analogue of cytidine

E. De Clercq, J. Montgomery, Y. Shealy, 1990, Biochemical Pharmacology.

Carbocyclic analogs of cytosine nucleosides

Y. Shealy, C. O'dell, 1980 .

Carbocyclic analogues of 5-substituted uracil nucleosides: synthesis and antiviral activity.

G. Arnett, Y. Shealy, W. Shannon, 1983, Journal of Medicinal Chemistry.

Carbocyclic Analogues of 5-Halocytosine Nucleosides

G. Arnett, W. C. Coburn, J. Riordan, 1987 .

Synthesis and antiviral activity of the carbocyclic analogues of 5-ethyl-2'-deoxyuridine and of 5-ethynyl-2'-deoxyuridine.

G. Arnett, Y. Shealy, W. Shannon, 1986, Journal of Medicinal Chemistry.

Inhibition of utilization of hypoxanthine and guanine in cells treated with the carbocyclic analog of adenosine. Phosphates of carbocyclic nucleoside analogs as inhibitors of hypoxanthine (guanine) phosphoribosyltransferase.

R. W. Brockman, L. Bennett, P. Allan, 1985, Molecular pharmacology.

Incorporation of the carbocyclic analog of 2'-deoxyguanosine into the DNA of herpes simplex virus and of HEp-2 cells infected with herpes simplex virus.

J. Montgomery, G. Arnett, W. Parker, 1992, Molecular Pharmacology.

Synthesis and antiviral activity of carbocyclic analogues of 2'-deoxyribofuranosides of 2-amino-6-substituted-purines and of 2-amino-6-substituted-8-azapurines.

G. Arnett, Y. Shealy, W. Shannon, 1984, Journal of Medicinal Chemistry.

Carbocyclic analogues of 5-fluorouracil nucleosides.

R. W. Brockman, S. Shaddix, N. Dubois, 1981, Journal of Medicinal Chemistry.

Synthesis and Antineoplastic Evaluation of α-Substituted Alkanesulfonates: Analogues of Clomesone

Y. Shealy, C. A. Krauth, 1993 .

Identification of 7-(2-hydroxyethyl)guanine as a product of alkylation of calf thymus DNA with clomesone.

R. Struck, L. Rose, Y. Shealy, 1991, Biochemical pharmacology.

Carbocyclic analogues of 5'-amino-5'-deoxy- and 3'-amino-3'-deoxythymidines.

G. Arnett, Y. Shealy, W. Shannon, 1986, Journal of medicinal chemistry.

CARBOCYCLIC ANALOGS OF 5-SUBSTITUTED URACIL NUCLEOSIDES. SYNTHESIS AND ANTIVIRAL ACTIVITY

G. Arnett, Y. Shealy, W. Shannon, 1983 .

Synthesis and Antiviral Activity of the Carbocyclic Analogues of S‐Ethyl‐T‐deoxyuridine and of 5‐Ethynyl‐2′‐deoxyuridine.

G. Arnett, Y. Shealy, W. Shannon, 1986 .

Carbocyclic Analogues of 3′,4′-Didehydro-2′-deoxyribofuranosyl-2,4(1H, 3H)-pyrimidinediones.

Y. Shealy, C. O'dell, 1995 .

CARBOCYCLIC ANALOGS OF 5-FLUOROURACIL NUCLEOSIDES

R. W. Brockman, S. Shaddix, N. Dubois, 1982 .

2-Chloroethyl (methylsulfonyl)methanesulfonate and related (methylsulfonyl)methanesulfonates. Antineoplastic activity in vivo.

W. Laster, Y. Shealy, C. A. Krauth, 1984, Journal of medicinal chemistry.

2-haloethylating agents for cancer chemotherapy. 2-haloethyl sulfonates.

J. Montgomery, R. Struck, Y. Shealy, 1983, Journal of medicinal chemistry.

Terminal bifunctional retinoids. Synthesis and evaluations related to cancer chemopreventive activity.

B. Sani, J. Riordan, Y. Shealy, 1988, Journal of medicinal chemistry.

v-Triazolo[4,5-d]pyrimidines. II. O-Substituted Derivatives of 8-Azaguanine and 8-Azahypoxanthine1

J. Montgomery, Y. Shealy, C. O'dell, 1962 .

Regulation of hepatic lecithin:retinol acyltransferase activity by retinoic acid receptor-selective retinoids.

A. Ross, W. Brouillette, T. Shimada, 1997, Archives of biochemistry and biophysics.

Inhibition of urinary bladder cancer by N-(ethyl)-all-trans-retinamide and N-(2-hydroxyethyl)-all-trans-retinamide in rats and mice.

M. Sporn, H. Thompson, C. Grubbs, 1981, Cancer research.

A Synthesis of Pregnane-3,20-dione from Stigmasterol and Ergosterol1

G. Slomp, J. Johnson, R. L. Pederson, 1955 .

Chemical properties and biological effects of 2-haloethyl sulfonates.

D. J. Adamson, G. P. Wheeler, B. Bowdon, 1984, Biochemical pharmacology.

Nonenzymatic isomerization of all-trans- and 13-cis-retinoids catalyzed by sulfhydryl groups.

T. Shih, D. Strother, Y. Shealy, 1986, Drug metabolism and disposition: the biological fate of chemicals.

Derivatives of 2,4-diamino-6-methylpteridine

J. Montgomery, R. D. Elliott, C. Temple, 1979 .

Triazenes of phenylbutyric, hydrocinnamic, phenoxyacetic, and benzoylglutamic acid derivatives.

W. Laster, Y. Shealy, C. E. Opliger, 1971, Journal of pharmaceutical sciences.

Influence of 15 retinoic acid amides on urinary bladder carcinogenesis in the mouse.

M. Sporn, D. Mccormick, R. Moon, 1982, Carcinogenesis.

Retinyl methyl ether down-regulates activator protein 1 transcriptional activation in breast cancer cells.

A. Agadir, X. Zhang, Y. Shealy, 1997, Cancer research.

Anhydroretinol, a retinoid active in preventing mammary cancer induced in rats by N-methyl-N-nitrosourea.

I. Eto, M. Juliana, B. Sani, 1998, Oncology reports.

Cancer Chemopreventive Retinoids: Validation and Analysis of in Vivo and in Vitro Bioassay Results

Jong Y. Park, J. Wille, Y. Shealy, 2016 .

Toxicologic and immunologic evaluations of N-(all-trans-retinoyl)-DL-leucine and N-(all-trans-retinoyl)glycine.

C. Lindamood, B. Sani, D. Dillehay, 1988, Toxicology and applied pharmacology.

Folic acid analogs. Modifications in the benzene‐ring region. 5. 2′,6′‐diazafolic acid

E. Roberts, Y. Shealy, 1974 .

1,2,5-Selenadiazoles. Synthesis and properties

Y. Shealy, J. D. Clayton, 1967 .

Acidic Cleavage of Amino[1,2,5]thiadiazolo[3,4-d]- and -v-triazolo[4,5-d]pyrimidines to 1,2,5-Thiadiazole-1 and v-Triazolecarboxamidines2

Y. Shealy, C. O'dell, 1965 .

Thiadiazoles. IV. 4-Ureido- and 4-Amino-1,2,5-thiadiazole-3-carboxylic Acid Derivatives from [1,2,5]Thiadiazolo[3,4-d]pyrimidine-5,7(4H,6H)- diones1

Y. Shealy, J. D. Clayton, 1964 .

Thiadiazoles. II. Formation of 4-Amino-1,2,5-thiadiazole-3-carboxylic Acid and Its Derivatives by Ring-Cleavage of [1,2,5]Thiadiazolo[3,4-d]pyrimidin-7(6H)-one1,2

Y. Shealy, J. D. Clayton, 1963 .

Synthetic and naturally occurring retinoids inhibit third- to fourth-stage larval development by Onchocerca lienalis in vitro.

J. Donnelly, J. Lok, B. Sani, 1990, Tropical medicine and parasitology : official organ of Deutsche Tropenmedizinische Gesellschaft and of Deutsche Gesellschaft fur Technische Zusammenarbeit (GTZ).

Synthesis and properties of some 13-cis- and all-trans-retinamides.

M. Sporn, M. Kirk, W. C. Coburn, 1984, Journal of pharmaceutical sciences.

v-Triazolo[4,5-d]pyrimidines. 3. N-(3-alkyl-5-amino-3H-v-triazolo[4,5-d]pyrimidin-7-yl)-amino acids.

J. Montgomery, Y. Shealy, C. O'dell, 1966, Journal of Medicinal Chemistry.

D- and L-thalidomide.

J. Montgomery, Y. Shealy, C. E. Opliger, 1965, Chemistry & industry.

Imidazoles. II. 5(or 4)-(Monosubstituted triazeno)imidazole-4(or 5)-carboxamides.

Y. Shealy, C. A. Krauth, 1966, Journal of medicinal chemistry.