Keisuke Motoki

Hypouricemic agents reduce indoxyl sulfate excretion by inhibiting the renal transporters OAT1/3 and ABCG2

T. Iwanaga, N. Ashizawa, T. Takada, 2021, Scientific Reports.

Depression of type I diacylglycerol kinases in pancreatic β-cells from male mice results in impaired insulin secretion.

Yosuke Kobayashi, Y. Shirai, T. Ishikawa, 2013, Endocrinology.

Discovery, optimization, and evaluation of non-bile acid FXR/TGR5 dual agonists

Sachiho Miyata, Tetsuya Taniguchi, Miku Sakai, 2021, Scientific Reports.

Identification of Human UDP-Glucuronosyltransferase and Sulfotransferase as Responsible for the Metabolism of Dotinurad, a Novel Selective Urate Reabsorption Inhibitor

T. Iwanaga, Seiichi Kobashi, K. Yamano, 2021, Drug Metabolism and Disposition.

Pharmacological Evaluation of Dotinurad, a Selective Urate Reabsorption Inhibitor

Koji Matsumoto, T. Iwanaga, N. Ashizawa, 2019, The Journal of Pharmacology and Experimental Therapeutics.

Pharmacokinetic/pharmacodynamic modeling and simulation of dotinurad, a novel uricosuric agent, in healthy volunteers

I. Tamai, T. Ohashi, T. Iwanaga, 2019, Pharmacology research & perspectives.