Jelena M. Telenius

发表

Role of neutral lipids in tear fluid lipid layer: coarse-grained simulation study.

I. Vattulainen, J. Holopainen, A. Koivuniemi, 2012, Langmuir : the ACS journal of surfaces and colloids.

Multipartite super-enhancers function in an orientation-dependent manner

Matthew E. Gosden, D. Downes, J. Hughes, 2022, bioRxiv.

The chromatin remodeller ATRX facilitates diverse nuclear processes, in a stochastic manner, in both heterochromatin and euchromatin

R. Schwessinger, Matthew E. Gosden, D. Downes, 2022, Nature Communications.

Dynamics of the 4D genome during in vivo lineage specification and differentiation

Daniel Hidalgo, M. Socolovsky, J. Telenius, 2020, Nature Communications.

Dynamic Runx1 chromatin boundaries affect gene expression in hematopoietic development

Lucas V. Greder, R. Schwessinger, D. Downes, 2021, bioRxiv.

Enhancers predominantly regulate gene expression during differentiation via transcription initiation.

R. Schwessinger, D. Downes, J. Hughes, 2021, Molecular cell.

The impact of lipid composition on the stability of the tear fluid lipid layer

I. Vattulainen, J. Holopainen, A. Koivuniemi, 2012 .

Molecular organization of the tear fluid lipid layer.

Jelena Telenius, Ilpo Vattulainen, Mikko Ritala, 2010, Biophysical journal.

NGseqBasic - a single-command UNIX tool for ATAC-seq, DNaseI-seq, Cut-and-Run, and ChIP-seq data mapping, high-resolution visualisation, and quality control

Jelena Telenius, Jim R. Hughes, J. Hughes, 2018, bioRxiv.

Editing an α-globin enhancer in primary human hematopoietic stem cells as a treatment for β-thalassemia

P. Sopp, P. Vyas, Matthew E. Gosden, 2017, Nature Communications.

A functional overlap between actively transcribed genes and chromatin boundary elements

Matthew E. Gosden, D. Downes, J. Hughes, 2020, bioRxiv.

Reactivation of a developmentally silenced embryonic globin gene

S. Orkin, L. Pennacchio, D. Downes, 2021, Nature Communications.

Chromatin interaction maps identify Wnt responsive cis-regulatory elements coordinating Paupar-Pax6 expression in neuronal cells

Keith W. Vance, J. Hughes, Robert J. Williams, 2021, bioRxiv.

Reconstruction of the global neural crest gene regulatory network in vivo

J. Telenius, J. Hughes, S. Taylor, 2018, bioRxiv.

A Dynamic Folded Hairpin Conformation Is Associated with α-Globin Activation in Erythroid Cells.

J. Telenius, J. Hughes, M. Nicodemi, 2020, Cell reports.

An integrated platform to systematically identify causal variants and genes for polygenic human traits

Calliope A. Dendrou, J. Todd, G. Lunter, 2019, bioRxiv.

DeepC: predicting 3D genome folding using megabase-scale transfer learning

Yee Whye Teh, Gerton Lunter, Jim R Hughes, 2020, Nature Methods.

DNA methylation of intragenic CpG islands depends on their transcriptional activity during differentiation and disease

E. Li, J. Hughes, D. Higgs, 2017, Proceedings of the National Academy of Sciences.

Genetic dissection of the α-globin super-enhancer in vivo

L. Pennacchio, J. Telenius, J. Hughes, 2016, Nature Genetics.

Multiplexed analysis of chromosome conformation at vastly improved sensitivity

J. Telenius, J. Hughes, S. McGowan, 2015, Nature Methods.

Sasquatch: predicting the impact of regulatory SNPs on transcription factor binding from cell- and tissue-specific DNase footprints

J. Telenius, R. Schwessinger, J. Hughes, 2017, Genome research.

Functional characterisation of cis-regulatory elements governing dynamic Eomes expression in the early mouse embryo

Jelena Telenius, Damien J Downes, Ita Costello, 2017, Development.

CaptureCompendium: a comprehensive toolkit for 3C analysis

J. Telenius, R. Schwessinger, D. Downes, 2020, bioRxiv.

Single-allele chromatin interactions identify regulatory hubs in dynamic compartmentalized domains

Simona Bianco, Mario Nicodemi, Damien J Downes, 2018, Nature Genetics.

DOT1L inhibition reveals a distinct subset of enhancers dependent on H3K79 methylation

P. Vyas, D. Downes, J. Hughes, 2019, Nature Communications.

Enhancers predominantly regulate gene expression in vivo via transcription initiation

M. Bender, R. Schwessinger, D. Downes, 2019, bioRxiv.

High-resolution targeted 3C interrogation of cis-regulatory element organization at genome-wide scale

R. Schwessinger, Matthew E. Gosden, D. Downes, 2021, Nature Communications.

Targeted high-resolution chromosome conformation capture at genome-wide scale

J. Telenius, R. Schwessinger, Matthew E. Gosden, 2020, bioRxiv.

A revised model for promoter competition based on multi-way chromatin interactions at the α-globin locus

J. Hughes, D. Higgs, A. M. Oudelaar, 2019, Nature Communications.

Structural Basis of Mechanochemical Coupling in a Hexameric Molecular Motor*

E. Mancini, D. Stuart, R. Tuma, 2008, Journal of Biological Chemistry.

A tissue-specific self-interacting chromatin domain forms independently of enhancer-promoter interactions

J. Hughes, D. Higgs, N. Roberts, 2017, bioRxiv.

Single-allele chromatin interactions identify regulatory hubs in dynamic compartmentalized domains

J. Dekker, R. Schwessinger, D. Downes, 2018, Nature Genetics.

DeepC: Predicting chromatin interactions using megabase scaled deep neural networks and transfer learning

Yee Whye Teh, Jelena Telenius, Gerton Lunter, 2019, bioRxiv.

DOT1L inhibition reveals a distinct subset of enhancers dependent on H3K79 methylation

P. Vyas, D. Downes, J. Hughes, 2018, bioRxiv.

How to Tackle Challenging ChIP-Seq, with Long-Range Cross-Linking, Using ATRX as an Example.

D. Higgs, R. Gibbons, Julia Truch, 2018, Methods in molecular biology.

Molecular dynamics simulations of the interactions of medicinal plant extracts and drugs with lipid bilayer membranes

Jelena Telenius, Wojciech Kopec, Himanshu Khandelia, 2013, The FEBS journal.

A gain-of-function single nucleotide variant creates a new promoter which acts as an orientation-dependent enhancer-blocker

D. Downes, J. Hughes, D. Higgs, 2021, Nature Communications.

Dissection of the 4D chromatin structure of the α-globin locus through in vivo erythroid differentiation with extreme spatial and temporal resolution

Daniel Hidalgo, M. Socolovsky, Matthew E. Gosden, 2019, bioRxiv.

Dynamic Runx1 chromatin boundaries affect gene expression in hematopoietic development

Lucas V. Greder, R. Schwessinger, D. Downes, 2022, Nature Communications.

RNA packaging motor: From structure to quantum mechanical modelling and sequential-stochastic mechanism

E. Mancini, J. Telenius, A. Wallin, 2008 .

Visualization of complex processes in lipid systems using computer simulations and molecular graphics.

Jelena Telenius, Ilpo Vattulainen, Luca Monticelli, 2009, Methods in molecular biology.

Lessons from the biophysics of interfaces: Lung surfactant and tear fluid

J. Telenius, I. Vattulainen, J. Holopainen, 2011, Progress in Retinal and Eye Research.

Editing an α-globin enhancer in primary human hematopoietic stem cells as a treatment for β-thalassemia

P. Sopp, P. Vyas, Matthew E. Gosden, 2017, Nature Communications.

Dynamics of the 4D genome during lineage specification, differentiation and maturation in vivo

Daniel Hidalgo, M. Socolovsky, Matthew E. Gosden, 2019 .

Single-cell chromatin interactions reveal regulatory hubs in dynamic compartmentalized domains

J. Dekker, J. Telenius, R. Schwessinger, 2018, bioRxiv.

Reconstruction of the Global Neural Crest Gene Regulatory Network In Vivo

J. Hughes, S. Taylor, T. Sauka-Spengler, 2019, Developmental cell.

A tissue-specific self-interacting chromatin domain forms independently of enhancer-promoter interactions

J. Telenius, J. Hughes, D. Higgs, 2017, Nature Communications.

High-Throughput Genotyping of CRISPR/Cas Edited Cells in 96-Well Plates

D. Downes, M. Suciu, Stephanie J. Hill, 2018, Methods and protocols.

Functional characterisation of cis-regulatory elements governing dynamic Eomes expression in the early mouse embryo

Claire S. Simon, D. Downes, D. Higgs, 2017, Development.

Dynamics of the 4D genome during in vivo lineage specification and differentiation

Daniel Hidalgo, M. Socolovsky, D. Higgs, 2020, Nature Communications.