M. Talbot

发表

Biology of Recombinant Hirudin (CGP 39393): A New Prospect in the Treatment of Thrombosis

M. Talbot, 1989, Seminars in thrombosis and hemostasis.

Recombinant hirudin: a new prospect in thrombosis.

M. Talbot, 1991, Current studies in hematology and blood transfusion.

The discovery of orally available thrombin inhibitors: studies towards the optimisation of CGH1668.

D. Janus, K. Menear, David J. Farr, 1998, Bioorganic & medicinal chemistry letters.

Studies towards the identification of potent, selective and bioavailable thrombin inhibitors.

D. Janus, K. Menear, D. Bentley, 1999, Bioorganic & medicinal chemistry letters.

The Characterisation of Thrombus Development in an Improved Model of Arterio-Venous Shunt Thrombosis in the Rat and the Effects of Recombinant Desulphatohirudin (CGP 39393), Heparin, and lloprost

R. Peters, R. Wallis, K. Mitchell, 1991, Thrombosis and Haemostasis.

The design and synthesis of thrombin inhibitors: analogues of MD805 containing non-polar surrogates for arginine at the P1 position.

D. Brundish, D. Janus, X. Cockcroft, 2000, Bioorganic & medicinal chemistry letters.

Design and synthesis of thrombin inhibitors: analogues of MD-805 with reduced stereogenicity and improved potency.

M. McDonnell, R. Wakeford, D. Brundish, 1999, Journal of Medicinal Chemistry.

The design and synthesis of thrombin inhibitors: the introduction of in vivo efficacy and oral bioavailability into benzthiazolylalanine inhibitors.

K. Menear, X. Cockcroft, M. Tweed, 2000, Bioorganic & medicinal chemistry letters.

The discovery of orally available thrombin inhibitors: optimisation of the P1 pharmacophore.

B. Wathey, D. Janus, K. Menear, 1999, Bioorganic & medicinal chemistry letters.

Recombinant Desulphatohirudin (CGP 39393) Anticoagulant and Antithrombotic Properties In Vivo

R. Peters, R. Wallis, K. Mitchell, 1989, Thrombosis and Haemostasis.

Quantification of lymphocyte activation by measurement of DNA polymerase α activity

M. K. Jasani, M. Talbot, 1985 .

The effects of recombinant desulphatohirudin on arterial thrombosis in rats.

R. Peters, R. Wallis, K. Mitchell, 1991, Haemostasis.

A non‐occlusive model of arterial thrombus formation in the rat and its modification by inhibitors of platelet function, or thrombin activity

J. Giddings, R. Wallis, S. Dolan, 1992, Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis.

Optimisation of the P2 pharmacophore in a series of thrombin inhibitors: ion-dipole interactions with lysine 60G.

M. Grütter, J. Priestle, B. Wathey, 1999, Bioorganic & Medicinal Chemistry Letters.