W. H. Irwin McLean

发表

SiRNA‐Mediated Selective Inhibition of Mutant Keratin mRNAs Responsible for the Skin Disorder Pachyonychia Congenita

M. Landthaler, R. Hickerson, R. Leube, 2006, Annals of the New York Academy of Sciences.

Keratin 9 Is Required for the Structural Integrity and Terminal Differentiation of the Palmoplantar Epidermis

J. McGrath, D. J. Fu, D. Lunny, 2013, The Journal of investigative dermatology.

Levels of filaggrin degradation products are influenced by both filaggrin genotype and atopic dermatitis severity

S. Kežić, A. Irvine, G. O’Regan, 2011, Allergy.

Atopic dermatitis increases the effect of exposure to peanut antigen in dust on peanut sensitization and likely peanut allergy

D. Stablein, H. Sampson, G. Lack, 2015, Pediatrics.

Plectin mutations underlie epidermolysis bullosa simplex in 8% of patients.

J. Jongbloed, L. Boven, M. Jonkman, 2014, The Journal of investigative dermatology.

Loss-of-Function Mutations in the Gene Encoding Filaggrin Are Not Strongly Associated with Chronic Actinic Dermatitis.

S. Ibbotson, S. Brown, L. Campbell, 2015, The Journal of investigative dermatology.

Patients with atopic dermatitis with filaggrin loss‐of‐function mutations show good but lower responses to immunosuppressive treatment

M. Leeflang, S. Kežić, P. Spuls, 2017, The British journal of dermatology.

Male genital lichen sclerosus and filaggrin

D. Hawkins, C. Bunker, A. Muneer, 2019, Clinical and experimental dermatology.

Filaggrin-stratified transcriptomic analysis of pediatric skin identifies mechanistic pathways in patients with atopic dermatitis

G. Barton, N. Schurch, C. Cole, 2014, The Journal of allergy and clinical immunology.

Heterozygous Mutations in AAGAB Cause Type 1 Punctate Palmoplantar Keratoderma with Evidence for Increased Growth Factor Signaling

W. Perkins, S. Brown, J. Salas-Alanis, 2013, The Journal of investigative dermatology.

Heritable Filaggrin Disorders: The Paradigm of Atopic Dermatitis.

A. Irvine, W. H. Irwin McLean, 2012, The Journal of investigative dermatology.

Genomic localization, organization and amplification of the human zinc transporter protein gene, ZNT4, and exclusion as a candidate gene in different clinical variants of acrodermatitis enteropathica

J. McGrath, N. Whittock, R. Mallipeddi, 2001, Archives of Dermatological Research.

Filaggrin null mutations are associated with increased asthma exacerbations in children and young adults

B. Lipworth, C. Palmer, S. Mukhopadhyay, 2008, Allergy.

Missense mutations in keratin 17 cause either pachyonychia congenita type 2 or a phenotype resembling steatocystoma multiplex.

E. Lane, D. Hohl, I. Leigh, 1997, The Journal of investigative dermatology.