K. Coughlan

发表

‘Pre-conditioning’ with Latrepirdine, an AMPK activator, delays ALS progression in SOD1 mice

M. Hogg, M. Mitchem, K. Coughlan, 2015 .

Acidotoxicity and acid-sensing ion channels contribute to motoneuron degeneration

J. Prehn, Á. Behan, M. Hogg, 2013, Cell Death and Differentiation.

Riluzole does not improve lifespan or motor function in three ALS mouse models

J. Prehn, M. Hogg, L. Halang, 2018, Amyotrophic lateral sclerosis & frontotemporal degeneration.

Apoptosis signal-regulating kinase 1 (ASK1) and HIF-1α protein are essential factors for nitric oxide-dependent accumulation of p53 in THP-1 human myeloid macrophages

V. Sumbayev, S. Nicholas, K. Coughlan, 2008, Apoptosis.

A high-fat jelly diet restores bioenergetic balance and extends lifespan in the presence of motor dysfunction and lumbar spinal cord motor neuron loss in TDP-43A315T mutant C57BL6/J mice

J. Prehn, L. Halang, I. Woods, 2016, Disease Models & Mechanisms.

Crucial involvement of xanthine oxidase in the intracellular signalling networks associated with human myeloid cell function

G. Lall, B. Gibbs, V. Sumbayev, 2014, Scientific Reports.

Dysfunctional mitochondria contain endogenous high-affinity human Toll-like receptor 4 (TLR4) ligands and induce TLR4-mediated inflammatory reactions.

L. Calzolai, G. Lall, I. Yasinska, 2011, The international journal of biochemistry & cell biology.

HIF-1alpha protein is an essential factor for protection of myeloid cells against LPS-induced depletion of ATP and apoptosis that supports Toll-like receptor 4-mediated production of IL-6.

V. Sumbayev, H. Lall, K. Coughlan, 2008, Molecular immunology.

The involvement of sphingosine kinase 1 in LPS‐induced Toll‐like receptor 4‐mediated accumulation of HIF‐1α protein, activation of ASK1 and production of the pro‐inflammatory cytokine IL‐6

J. Nunes, J. Waxman, V. Sumbayev, 2011, Immunology and cell biology.

The BCL-2 family protein Bid is critical for pro-inflammatory signaling in astrocytes

J. Prehn, Hans-Georg König, S. Kinsella, 2014, Neurobiology of Disease.

The BCL-2 family protein Bid is critical for pro-inflammatory signaling in astrocytes Running title : Bid and NF-κ B activation

Hans-Georg König, S. Kinsella, B. Breen, 2015 .

Motoneurons Secrete Angiogenin to Induce RNA Cleavage in Astroglia

Philippe Marin, P. Marin, C. Concannon, 2012, The Journal of Neuroscience.

Preconditioning " with latrepirdine , an adenosine 5 '-monophosphate-activated protein kinase activator , delays amyotrophic lateral sclerosis progression in SOD 1 ( G 93 A ) mice

J. Prehn, M. Hogg, M. Mitchem, 2015 .

Pleiotropic activity of systemically delivered angiogenin in the SOD1G93A mouse model

J. Prehn, M. Hogg, S. Lewandowski, 2018, Neuropharmacology.

Correction: Vascular regression precedes motor neuron loss in the FUS (1-359) ALS mouse model

J. Prehn, M. Hogg, S. Lewandowski, 2019, Disease Models & Mechanisms.

Brain-Targeted Proanthocyanidin Metabolites for Alzheimer's Disease Treatment

Sara M. Levens, A. Kania, S. Perlmutter, 2012, The Journal of Neuroscience.

The involvement of sphingosine kinase 1 in LPS‐induced Toll‐like receptor 4‐mediated accumulation of HIF‐1α protein, activation of ASK1 and production of the pro‐inflammatory cytokine IL‐6

J. Nunes, J. Waxman, V. Sumbayev, 2011, Immunology and cell biology.

Dysfunctional mitochondria contain endogenous high-affinity human Toll-like receptor 4 (TLR4) ligands and induce TLR4-mediated inflammatory reactions.

L. Calzolai, G. Lall, I. Yasinska, 2011, The international journal of biochemistry & cell biology.

“Preconditioning” with latrepirdine, an adenosine 5′-monophosphate-activated protein kinase activator, delays amyotrophic lateral sclerosis progression in SOD1G93A mice

J. Prehn, M. Hogg, M. Mitchem, 2015, Neurobiology of Aging.