I. Poulton

发表

niches and their depletion mobilizes HSCs Bone marrow macrophages maintain hematopoietic stem cell (HSC)

J. Lévesque, I. Winkler, N. Rooijen, 2010 .

RARγ is a negative regulator of osteoclastogenesis

T. Martin, N. Sims, M. Gillespie, 2015, The Journal of Steroid Biochemistry and Molecular Biology.

Absence of Calcitriol Causes Increased Lactational Bone Loss and Lower Milk Calcium but Does Not Impair Post‐lactation Bone Recovery in Cyp27b1 Null Mice

C. Kovacs, Yue Ma, I. J. Poulton, 2018, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Dmp1Cre‐directed knockdown of parathyroid hormone–related protein (PTHrP) in murine decidua is associated with a life‐long increase in bone mass, width, and strength in male progeny

T. Martin, C. Kovacs, I. J. Poulton, 2021, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

G‐CSF Receptor Deletion Amplifies Cortical Bone Dysfunction in Mice With STAT3 Hyperactivation in Osteocytes

I. Wicks, N. Sims, Jonathan H. Gooi, 2022, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Bone corticalization requires local SOCS3 activity and is promoted by androgen action via interleukin-6

T. Martin, David Handelsman, Rachelle W Johnson, 2017, Nature Communications.

Ciliary Neurotrophic Factor Inhibits Bone Formation and Plays a Sex-Specific Role in Bone Growth and Remodeling

T. Martin, N. Sims, J. Quinn, 2010, Calcified Tissue International.

Dmp1Cre-directed knockdown of PTHrP in murine decidua is associated with increased bone width and a life-long increase in strength specific to male progeny

T. Martin, C. Kovacs, I. J. Poulton, 2020, bioRxiv.

Vaginally Administered PEGylated LIF Antagonist Blocked Embryo Implantation and Eliminated Non-Target Effects on Bone in Mice

H. Butzkueven, N. Sims, N. Nicola, 2011, PloS one.

Cortical bone maturation in mice requires SOCS3 suppression of gp130/STAT3 signalling in osteocytes

T. Martin, N. Sims, E. C. Walker, 2020, eLife.

Contrasting roles of leukemia inhibitory factor in murine bone development and remodeling involve region‐specific changes in vascularization

N. Sims, E. C. Walker, S. Pompolo, 2012, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Cardiotrophin‐1 Is an Osteoclast‐Derived Stimulus of Bone Formation Required for Normal Bone Remodeling

N. Sims, M. Gillespie, J. Quinn, 2008, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Calcitriol‐Dependent and ‐Independent Regulation of Intestinal Calcium Absorption, Osteoblast Function, and Skeletal Mineralization during Lactation and Recovery in Mice

C. Kovacs, N. Sims, Narelle E. McGregor, 2022, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

EphrinB2 signaling in osteoblasts promotes bone mineralization by preventing apoptosis

T. Martin, N. Sims, S. Tonna, 2014, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

The Primary Function of gp130 Signaling in Osteoblasts Is To Maintain Bone Formation and Strength, Rather Than Promote Osteoclast Formation

Rachelle W Johnson, I. J. Poulton, N. Sims, 2014, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Adverse effects of valproate on bone: Defining a model to investigate the pathophysiology

J. Wark, N. Sims, M. Morris, 2010, Epilepsia.

Bone marrow macrophages maintain hematopoietic stem cell (HSC) niches and their depletion mobilizes HSCs.

J. Lévesque, I. Winkler, N. Van Rooijen, 2010, Blood.

Ubiquitous expression of the Pik3caH1047R mutation promotes hypoglycemia, hypoinsulinemia, and organomegaly

J. Malaterre, G. McArthur, M. Bywater, 2015, The FASEB Journal.

promotes hypoglycemia, hypoinsulinemia, and organomegaly

J. Malaterre, G. McArthur, M. Bywater, 2015 .

Autocrine and Paracrine Regulation of the Murine Skeleton by Osteocyte‐Derived Parathyroid Hormone‐Related Protein

T. Martin, I. J. Poulton, N. Sims, 2018, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Severe developmental bone phenotype in ClC-7 deficient mice.

M. Karsdal, D. Felsenberg, T. Martin, 2010, Developmental biology.

Lack of sustained response to teriparatide in a patient with adult hypophosphatasia.

P. Ebeling, I. J. Poulton, N. Sims, 2010, The Journal of clinical endocrinology and metabolism.

Murine Oncostatin M Acts via Leukemia Inhibitory Factor Receptor to Phosphorylate Signal Transducer and Activator of Transcription 3 (STAT3) but Not STAT1, an Effect That Protects Bone Mass*

G. Smyth, Yifang Hu, B. Jenkins, 2016, The Journal of Biological Chemistry.

STAT3 Hyperactivation Due to SOCS3 Deletion in Murine Osteocytes Accentuates Responses to Exercise‐ and Load‐Induced Bone Formation

S. Windahl, N. Sims, E. C. Walker, 2021, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

IL-6 exhibits both cis- and trans-signaling in osteocytes and osteoblasts, but only trans-signaling promotes bone formation and osteoclastogenesis

T. Martin, I. J. Poulton, N. Sims, 2019, The Journal of Biological Chemistry.

Bone corticalization requires local SOCS3 activity and is promoted by androgen action via interleukin-6

T. Martin, David Handelsman, Rachelle W Johnson, 2017, Nature Communications.

Bone Geometry Is Altered by Follistatin‐Induced Muscle Growth in Young Adult Male Mice

T. Martin, N. Sims, G. Lynch, 2021, JBMR plus.

Chondrocytic ephrin B2 promotes cartilage destruction by osteoclasts in endochondral ossification

T. Martin, N. Sims, S. Tonna, 2016, Development.

Loss of Gsα in the Postnatal Skeleton Leads to Low Bone Mass and a Blunted Response to Anabolic Parathyroid Hormone Therapy*

Min Chen, L. Weinstein, P. Aarnisalo, 2015, The Journal of Biological Chemistry.

Gsα enhances commitment of mesenchymal progenitors to the osteoblast lineage but restrains osteoblast differentiation in mice.

M. Selig, Min Chen, L. Weinstein, 2011, The Journal of clinical investigation.

Osteoclast Inhibitory Lectin, an Immune Cell Product That Is Required for Normal Bone Physiology in Vivo*

T. Martin, M. Smyth, I. J. Poulton, 2008, Journal of Biological Chemistry.

Osteoblasts Are Rapidly Ablated by Virus-Induced Systemic Inflammation following Lymphocytic Choriomeningitis Virus or Pneumonia Virus of Mice Infection in Mice

P. Foster, H. Rosenberg, N. Sims, 2018, The Journal of Immunology.

IL-6 trans-signalling mediates trabecular, but not cortical, bone loss after ovariectomy.

N. Sims, W. Ferlin, Narelle E. McGregor, 2018, Bone.

Oncostatin M promotes bone formation independently of resorption when signaling through leukemia inhibitory factor receptor in mice.

T. Martin, N. Sims, M. Gillespie, 2010, The Journal of clinical investigation.

Strain-Dependent Differences in Bone Development, Myeloid Hyperplasia, Morbidity and Mortality in Ptpn2-Deficient Mice

M. Tremblay, N. Sims, D. Godfrey, 2012, PloS one.

Glycoprotein130 (Gp130)/interleukin-6 (IL-6) signalling in osteoclasts promotes bone formation in periosteal and trabecular bone.

T. Martin, Rachelle W Johnson, N. Sims, 2015, Bone.

Sustained RANKL response to parathyroid hormone in oncostatin M receptor‐deficient osteoblasts converts anabolic treatment to a catabolic effect in vivo

N. Sims, E. C. Walker, Julie M. Quach, 2012, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Germline deletion of AMP‐activated protein kinase β subunits reduces bone mass without altering osteoclast differentiation or function

B. Kemp, I. J. Poulton, N. Sims, 2010, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Mice lacking AMP-activated kinase (AMPK) subunits β1 or β2 have low bone mass, while AICAR acts AMPK-independently to increase osteoclast formation

B. Kemp, N. Sims, M. Gillespie, 2009 .

The effect of carbamazepine on bone structure and strength in control and osteogenesis imperfecta (Col1a2 +/p.G610C ) mice

N. Sims, J. Bateman, L. Rowley, 2022, bioRxiv.

gp130 in late osteoblasts and osteocytes is required for PTH-induced osteoblast differentiation.

T. Martin, Rachelle W Johnson, I. J. Poulton, 2014, The Journal of endocrinology.

Testing Bone Formation Induction by Calvarial Injection Assay in vivo.

N. Sims, E. C. Walker, Narelle E. McGregor, 2020, Bio-protocol.

Bone corticalization requires local SOCS3 activity and is promoted by androgen action via interleukin-6

David Handelsman, N. Sims, Jonathan H. Gooi, 2017, Nature Communications.

Prepubertal Di-n-Butyl Phthalate Exposure Alters Sertoli and Leydig Cell Function and Lowers Bone Density in Adult Male Mice.

Amanda Bielanowicz, Rachelle W Johnson, Hoey Goh, 2016, Endocrinology.