C. Guntermann

发表

Human immunodeficiency virus infection abolishes CD4-dependent activation of ZAP-70 by inhibition of p56lck.

J. Dye, K. Nye, C. Guntermann, 1997, Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association.

CTLA-4 Suppresses Proximal TCR Signaling in Resting Human CD4+ T Cells by Inhibiting ZAP-70 Tyr319 Phosphorylation: A Potential Role for Tyrosine Phosphatases1

D. Alexander, C. Guntermann, 2002, The Journal of Immunology.

Resting Lymphocyte Kinase (Rlk/Txk) Targets Lymphoid Adaptor SLP-76 in the Cooperative Activation of Interleukin-2 Transcription in T-cells*

H. Schneider, C. Rudd, B. Guérette, 2000, The Journal of Biological Chemistry.

The effects of CD3, CD4 and CD28 signaling on lymphocytes during human immunodeficiency virus‐1 infection

K. Nye, R. Zheng, C. Guntermann, 1997, European journal of immunology.

The CD45 tyrosine phosphatase regulates Campath-1H (CD52)-induced TCR-dependent signal transduction in human T cells.

D. Alexander, G. Hale, S. Damjanovich, 2000, International immunology.

CTLA-4 Suppresses Proximal TCR Signaling

D. Alexander, C. Guntermann, 2002 .

A Potential Role for Tyrosine Phosphatases Phosphorylation : 319 Inhibiting ZAP-70 Tyr T Cells by + in Resting Human CD 4 CTLA-4 Suppresses Proximal TCR Signaling

D. Alexander, C. Guntermann, 2002 .

Impaired CD45-associated tyrosine phosphatase activity during HIV-1 infection: implications for CD3 and CD4 receptor signalling.

N. Amft, B. Murphy, K. Nye, 1998, Biochemical and biophysical research communications.

Lack of evidence for expression and function of IL-39 in human immune cells

Simone Schleeger, C. Guntermann, J. Weiss, 2020, PloS one.

Human immunodeficiency virus-1 infection requires pertussis toxin sensitive G-protein-coupled signalling and mediates cAMP downregulation.

A. Qureshi, P. Eagles, B. Murphy, 1999, Biochemical and biophysical research communications.

Interferon regulatory factor 5 and nuclear factor kappa‐B exhibit cooperating but also divergent roles in the regulation of pro‐inflammatory cytokines important for the development of TH1 and TH17 responses

B. Kinzel, T. Stein, A. Billich, 2018, The FEBS journal.

c-Kit-positive ILC2s exhibit an ILC3-like signature that may contribute to IL-17-mediated pathologies

Y. Shrestha, J. Koster, H. Spits, 2019, Nature Immunology.

Gene silencing of HIV chemokine receptors using ribozymes and single-stranded antisense RNA.

Sihem Cheloufi, Amer N Qureshi, P. Eagles, 2006, The Biochemical journal.

Retinoic-acid-orphan-receptor-C inhibition suppresses Th17 cells and induces thymic aberrations.

S. Hintermann, D. Theil, D. Patel, 2017, JCI insight.

Structure-based and property-driven optimization of N-aryl imidazoles towards potent and selective oral RORγt inhibitors.

S. Hintermann, P. Ertl, M. Streiff, 2019, Journal of medicinal chemistry.

Optimizing a Weakly Binding Fragment into a Potent RORγt Inverse Agonist with Efficacy in an in Vivo Inflammation Model.

S. Hintermann, R. Wolf, A. Vulpetti, 2018, Journal of medicinal chemistry.

Molecular immunopathogenesis of HIV infection.

W. Morrow, A. Pinching, T. T. Ng, 1996, Genitourinary medicine.

Topological Requirements and Signaling Properties of T Cell–activating, Anti-CD28 Antibody Superagonists

T. Hanke, I. Müller, T. Hünig, 2003, The Journal of experimental medicine.

Pharmacological inhibition of RORγt suppresses the Th17 pathway and alleviates arthritis in vivo

S. Hintermann, K. Kaupmann, J. Kallen, 2017, PloS one.

The Potent Protein Kinase C-Selective Inhibitor AEB071 (Sotrastaurin) Represents a New Class of Immunosuppressive Agents Affecting Early T-Cell Activation

Gerhard Zenke, Volker Brinkmann, Jiri Kovarik, 2009, Journal of Pharmacology and Experimental Therapeutics.

Antagonizing Retinoic Acid-Related-Orphan Receptor Gamma Activity Blocks the T Helper 17/Interleukin-17 Pathway Leading to Attenuated Pro-inflammatory Human Keratinocyte and Skin Responses

S. Hintermann, K. Kaupmann, D. Orain, 2019, Front. Immunol..

Structural States of RORγt: X‐ray Elucidation of Molecular Mechanisms and Binding Interactions for Natural and Synthetic Compounds

S. Hintermann, K. Kaupmann, J. Kallen, 2017, ChemMedChem.

Synthesis and Biological Evaluation of New Triazolo‐ and Imidazolopyridine RORγt Inverse Agonists

S. Hintermann, A. Vulpetti, K. Kaupmann, 2016, ChemMedChem.

c-Kit-positive ILC2s exhibit an ILC3-like signature that may contribute to IL-17-mediated pathologies

Y. Shrestha, J. Koster, H. Spits, 2019, Nature Immunology.

Structural States of RORγt: X‐ray Elucidation of Molecular Mechanisms and Binding Interactions for Natural and Synthetic Compounds

S. Hintermann, K. Kaupmann, J. Kallen, 2017, ChemMedChem.

The Potent Protein Kinase C-Selective Inhibitor AEB071 (Sotrastaurin) Represents a New Class of Immunosuppressive Agents Affecting Early T-Cell Activation

H. Towbin, G. Baier, V. Brinkmann, 2009, Journal of Pharmacology and Experimental Therapeutics.