J. Wolak

发表

Identification of Epstein-Barr nuclear antigen polypeptide in mouse and monkey cells after gene transfer with a cloned 2.9-kilobase-pair subfragment of the genome.

J. Robinson, W. P. Summers, D. Shedd, 1984, Proceedings of the National Academy of Sciences of the United States of America.

5-Aminomethyl-1H-benzimidazoles as orally active inhibitors of inducible T-cell kinase (Itk).

R. DesJarlais, J. Woska, C. Cywin, 2008, Bioorganic & medicinal chemistry letters.

Discovery, SAR and X-ray structure of 1H-benzimidazole-5-carboxylic acid cyclohexyl-methyl-amides as inhibitors of inducible T-cell kinase (Itk).

B. Tomczuk, R. DesJarlais, D. Ryan, 2008, Bioorganic & medicinal chemistry letters.

Loss of myeloid differentiation antigens precedes blastic transformation in chronic myelogenous leukemia.

S. Markowitz, H. Malech, T. Jennings, 1987, Blood.

Hit-to-lead studies on benzimidazole inhibitors of ITK: discovery of a novel class of kinase inhibitors.

Noel S. Wilson, C. Cywin, G. Roth, 2007, Bioorganic & medicinal chemistry letters.

Optimization of 2-phenylaminoimidazo[4,5-h]isoquinolin-9-ones: orally active inhibitors of lck kinase.

J. Peterson, S. Pav, N. Moss, 2003, Journal of medicinal chemistry.

Three Mechanistically Distinct Kinase Assays Compared: Measurement of Intrinsic ATPase Activity Identified the Most Comprehensive Set of ITK Inhibitors

Mohammed A. Kashem, Richard M. Nelson, Carol Ann Homon, 2007, Journal of biomolecular screening.

Hit to lead account of the discovery of a new class of inhibitors of Pim kinases and crystallographic studies revealing an unusual kinase binding mode.

C. Homon, B. Farmer, K. Qian, 2009, Journal of medicinal chemistry.

Discovery of potent inhibitors of interleukin-2 inducible T-cell kinase (ITK) through structure-based drug design.

G. Roth, Ji Wang, M. Kashem, 2009, Bioorganic & medicinal chemistry letters.

Discovery of potent and selective PKC-θ inhibitors

Mario G. Cardozo, Mohammed A. Kashem, Carol Ann Homon, 2007 .

Discovery of potent and selective PKC-theta inhibitors.

Mohammed A Kashem, C. Homon, J. Woska, 2007, Bioorganic & medicinal chemistry letters.

5-Aminomethyl-1H-benzimidazoles as orally active inhibitors of inducible T-cell kinase (Itk).

R. DesJarlais, J. Woska, C. Cywin, 2008, Bioorganic & medicinal chemistry letters.