S. Levak‐Frank

发表

Endogenously produced lipoprotein lipase enhances the binding and cell association of native, mildly oxidized and moderately oxidized low-density lipoprotein in mouse peritoneal macrophages.

R. Zimmermann, J. Greilberger, G. Jürgens, 1999, The Biochemical journal.

Uncoupling proteins 2 and 3 are fundamental for mitochondrial Ca2+ uniport

W. Graier, R. Malli, I. Fertschai, 2007, Nature Cell Biology.

Macrophage adipose triglyceride lipase deficiency attenuates atherosclerotic lesion development in LDL receptor knockout mice

R. Zechner, J. Kuiper, T. J. Berkel, 2012 .

Intercellular signalling within vascular cells under high D-glucose involves free radical-triggered tyrosine kinase activation

M. Hecker, W. Graier, A. Wagner, 2003, Diabetologia.

Novel amino-β-lactam derivatives as potent cholesterol absorption inhibitors

Sascha Obrowsky, D. Kratky, K. Molčanov, 2014, European journal of medicinal chemistry.

Trophoblast-like human choriocarcinoma cells serve as a suitable in vitro model for selective cholesteryl ester uptake from high density lipoproteins.

G. Desoye, A. Hammer, C. Wadsack, 2003, European journal of biochemistry.

Scavenger receptor class B, type I is expressed in porcine brain capillary endothelial cells and contributes to selective uptake of HDL‐associated vitamin E

D. R. van der Westhuyzen, E. Malle, W. Sattler, 2001, Journal of neurochemistry.

Fatty acids liberated from high-density lipoprotein phospholipids by endothelial-derived lipase are incorporated into lipids in HepG2 cells.

M. Hayn, S. Frank, S. Levak-Frank, 2003, The Biochemical journal.

Endothelial cell-derived lipase mediates uptake and binding of high-density lipoprotein (HDL) particles and the selective uptake of HDL-associated cholesterol esters independent of its enzymic activity.

R. Zechner, R. Zimmermann, D. Kratky, 2002, The Biochemical journal.

Lipoprotein lipase controls fatty acid entry into adipose tissue, but fat mass is preserved by endogenous synthesis in mice deficient in adipose tissue lipoprotein lipase.

J. Friedman, R. Zechner, H. Radner, 1997, Proceedings of the National Academy of Sciences of the United States of America.

Muscle-specific overexpression of lipoprotein lipase causes a severe myopathy characterized by proliferation of mitochondria and peroxisomes in transgenic mice.

R. Stollberger, R. Zechner, H. Radner, 1995, The Journal of clinical investigation.

Loss of intestinal GATA4 prevents diet-induced obesity and promotes insulin sensitivity in mice.

C. Diwoky, R. Stollberger, Sascha Obrowsky, 2011, American journal of physiology. Endocrinology and metabolism.

Macrophage Adipose Triglyceride Lipase Deficiency Attenuates Atherosclerotic Lesion Development in Low-Density Lipoprotein Receptor Knockout Mice

R. Zechner, T. V. van Berkel, J. Kuiper, 2011, Arteriosclerosis, thrombosis, and vascular biology.

Intestinal GATA4 deficiency protects from diet-induced hepatic steatosis

Sascha Obrowsky, D. Kratky, M. Battle, 2012, Journal of hepatology.

Farnesoid X receptor represses hepatic human APOA gene expression.

K. Kostner, A. Baghdasaryan, M. Trauner, 2011, The Journal of clinical investigation.

Lack of acyl-CoA:diacylglycerol acyltransferase 1 reduces intestinal cholesterol absorption and attenuates atherosclerosis in apolipoprotein E knockout mice

H. Ahammer, Sascha Obrowsky, D. Kratky, 2011, Biochimica et biophysica acta.

Identification of the human analog of SR-BI and LOX-1 as receptors for hypochlorite-modified high density lipoprotein on human umbilical venous endothelial cells.

R. Heller, O. Quehenberger, G. Marsche, 2001, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Triacylglycerol Accumulation Activates the Mitochondrial Apoptosis Pathway in Macrophages

S. Kohlwein, R. Zechner, D. Kratky, 2011, The Journal of Biological Chemistry.

Regulated expression of endothelial lipase by porcine brain capillary endothelial cells constituting the blood–brain barrier

D. Rader, A. Hammer, E. Malle, 2005, Journal of neurochemistry.

ABCA1 and Scavenger Receptor Class B, Type I, Are Modulators of Reverse Sterol Transport at an in Vitro Blood-Brain Barrier Constituted of Porcine Brain Capillary Endothelial Cells*

Z. Balázs, E. Malle, U. Panzenboeck, 2002, The Journal of Biological Chemistry.

Tissue‐specific expression of human lipoprotein lipase in the vascular system affects vascular reactivity in transgenic mice

R. Zechner, M. Frieden, W. Graier, 2002, British journal of pharmacology.

In muscle-specific lipoprotein lipase-overexpressing mice, muscle triglyceride content is increased without inhibition of insulin-stimulated whole-body and muscle-specific glucose uptake.

J. Romijn, L. Havekes, D. Kratky, 2001, Diabetes.

Lipoprotein lipase mediates the uptake of glycated LDL in fibroblasts, endothelial cells, and macrophages.

R. Zimmermann, W. Graier, O. Glatter, 2001, Diabetes.

Induced mutant mouse lines that express lipoprotein lipase in cardiac muscle, but not in skeletal muscle and adipose tissue, have normal plasma triglyceride and high-density lipoprotein-cholesterol levels.

R. Zechner, H. Radner, J. Breslow, 1999, Proceedings of the National Academy of Sciences of the United States of America.

Induced Mutant Mice Expressing Lipoprotein Lipase Exclusively in Muscle Have Subnormal Triglycerides yet Reduced High Density Lipoprotein Cholesterol Levels in Plasma*

R. Zechner, J. Breslow, R. Ramakrishnan, 1997, The Journal of Biological Chemistry.

Muscle-specific overexpression of human lipoprotein lipase in mice causes increased intracellular free fatty acids and induction of peroxisomal enzymes.

H. Radner, C. Noehammer, S. Schauer, 1997, Biochimie.

Severe hypertriglyceridemia, reduced high density lipoprotein, and neonatal death in lipoprotein lipase knockout mice. Mild hypertriglyceridemia with impaired very low density lipoprotein clearance in heterozygotes.

R. Zechner, H. Radner, J. Breslow, 1995, The Journal of clinical investigation.

The tissue distribution of lipoprotein lipase determines where chylomicrons bind

R. Zechner, T. Olivecrona, G. Olivecrona, 2015, Journal of Lipid Research.

Cholesteryl ester hydrolase activity is abolished in HSL macrophages but unchanged in macrophages lacking KIAA1363

R. Zechner, B. Cravatt, K. Chiang, 2010, Journal of Lipid Research.

Mobilization of cholesterol and fatty acids from choles-

R. Zechner, B. Cravatt, K. Chiang, 2010 .

Adipose triglyceride lipase is a TG hydrolase of the small intestine and regulates intestinal PPARα signaling

S. Schlager, Sascha Obrowsky, D. Kratky, 2013, Journal of Lipid Research.

The role of lipoprotein lipase in adipose tissue development and metabolism

R. Zechner, D. Kratky, S. Frank, 2000, International Journal of Obesity.

Identification of the human analog of SR‐BI and LOX‐1 as receptors for hypochlorite‐modified high‐density lipoprotein on human umbilical venous endothelial cells

R. Heller, O. Quehenberger, G. Marsche, 2001 .

Selective cholesteryl ester uptake from high density lipoprotein by human first trimester and term villous trophoblast cells.

G. Desoye, A. Hammer, K. Kozarsky, 2003, Placenta.

Efficient Phagocytosis Requires Triacylglycerol Hydrolysis by Adipose Triglyceride Lipase

R. Zechner, G. Haemmerle, D. Kratky, 2010, The Journal of Biological Chemistry.

Implications of endogenous and exogenous lipoprotein lipase for the selective uptake of HDL3-associated cholesteryl esters by mouse peritoneal macrophages.

R. Zechner, R. Zimmermann, G. Kostner, 1997, Journal of lipid research.

Cholesteryl ester accumulation and accelerated cholesterol absorption in intestine-specific hormone sensitive lipase-null mice

Sascha Obrowsky, G. Haemmerle, D. Kratky, 2012, Biochimica et biophysica acta.

Synthetic LXR agonist suppresses endogenous cholesterol biosynthesis and efficiently lowers plasma cholesterol.

Sascha Obrowsky, D. Kratky, U. Kompella, 2011, Current pharmaceutical biotechnology.

Synthetic LXR agonist attenuates plaque formation in apoE-/- mice without inducing liver steatosis and hypertriglyceridemia

M. Miyazaki, H. Ahammer, M. Trauner, 2009, Journal of Lipid Research.

Muscle-specific overexpression of lipoprotein lipase in transgenic mice results in increased alpha-tocopherol levels in skeletal muscle.

R. Zechner, H. Radner, W. Sattler, 1996, The Biochemical journal.

Scavenger receptor class B, type I on non-malignant and malignant human epithelial cells mediates cholesteryl ester-uptake from high density lipoproteins.

A. Hammer, K. Kozarsky, C. Wadsack, 2003, The international journal of biochemistry & cell biology.

Intestinal GATA4 deficiency induces proximal fibroblast growth factor 15 expression and represses hepatic gluconeogenesis.

Sascha Obrowsky, D. Kratky, S. Levak‐Frank, 2013, Journal of hepatology.