A. Lopez

发表

TLR7 gain-of-function genetic variation causes human lupus

T. Andrews, J. Lupski, V. Pascual, 2022, Nature.

Interaction of GM‐CSF and IL‐3 with the common β‐chain of their receptors

M. F. Shannon, C. Bagley, J. Woodcock, 1995, Journal of leukocyte biology.

Interleukin (IL)-1O, but not IL-4 or IL-13, Inhibits Cytokine Production and Growth in Juvenile Myelomonocytic Leukemia Cells1

S. Bonder, P. Hart, Claudine, 2006 .

The Apoptosis-inducing Granulocyte-Macrophage Colony-stimulating Factor (GM-CSF) Analog E21R Functions through Specific Regions of the Heterodimeric GM-CSF Receptor and Requires Interleukin-1β-converting Enzyme-like Proteases*

B. Nelson, A. Miyajima, Sharad Kumar, 1997, The Journal of Biological Chemistry.

Residue 21 of human granulocyte‐macrophage colony‐stimulating factor is critical for biological activity and for high but not low affinity binding.

M. F. Shannon, M. Vadas, M. Dottore, 1992, The EMBO journal.

Identification of a Cys Motif in the Common β Chain of the Interleukin 3, Granulocyte-Macrophage Colony-stimulating Factor, and Interleukin 5 Receptors Essential for Disulfide-linked Receptor Heterodimerization and Activation of All Three Receptors*

Q. Sun, C. Bagley, J. Woodcock, 1998, The Journal of Biological Chemistry.

HEMATOPOIESIS Identiﬁcation of a 14-3-3 Binding Sequence in the Common b Chain of the Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF), Interleukin-3 (IL-3), and IL-5 Receptors That Is Serine-Phosphorylated by GM-CSF

M. Dottore, C. Bagley, M. Berndt, 1999 .

Dissociation of TNF‐alpha cytotoxic and proinflammatory activities by p55 receptor‐ and p75 receptor‐selective TNF‐alpha mutants.

William B. Smith, P. Vandenabeele, J. Gamble, 1994, The EMBO journal.

Three residues in the common beta chain of the human GM‐CSF, IL‐3 and IL‐5 receptors are essential for GM‐CSF and IL‐5 but not IL‐3 high affinity binding and interact with Glu21 of GM‐CSF.

J. Tavernier, G. Plaetinck, C. Bagley, 1994, The EMBO journal.

Tumour necrosis factor‐alpha (TNF‐α): The good, the bad and potentially very effective

J. Barbara, X. Ostade, A. Lopez, 1996 .

A Discontinuous Eight-Amino Acid Epitope in Human Interleukin-3 Binds the α-Chain of Its Receptor*

M. Vadas, C. Bagley, B. Cambareri, 1996, The Journal of Biological Chemistry.

A dual role for the N-terminal domain of the IL-3 receptor in cell signalling

M. Dottore, Angel F. Lopez, T. Nero, 2018, Nature Communications.

Autocrine production and action of IL-3 and granulocyte colony-stimulating factor in chronic myeloid leukemia.

C. Eaves, T. Holyoake, Xiaoyan Jiang, 1999, Proceedings of the National Academy of Sciences of the United States of America.

Structure-function studies of human granulocyte-macrophage colony-stimulating factor. Identification of residues required for activity.

M. Vadas, S. Kent, L. To, 1988, Journal of immunology.

Inhibition of granulocyte-macrophage colony-stimulating factor prevents dissemination and induces remission of juvenile myelomonocytic leukemia in engrafted immunodeficient mice.

P. Iversen, I. Lewis, C. Niemeyer, 1997, Blood.

Deoxyribonucleic acid triplex formation inhibits granulocyte macrophage colony-stimulating factor gene expression and suppresses growth in juvenile myelomonocytic leukemic cells.

M. F. Shannon, P. Iversen, A. Lopez, 1997, The Journal of clinical investigation.

Regulation of neutrophil apoptosis by tumor necrosis factor-alpha: requirement for TNFR55 and TNFR75 for induction of apoptosis in vitro.

C. Haslett, X. Van Ostade, E. Chilvers, 1997, Blood.

Fractionated populations of normal human marrow cells respond to both human colony-stimulating factors with granulocyte-macrophage activity.

C. Begley, N. Nicola, D. Metcalf, 1985, Experimental hematology.

Puma indirectly activates Bax to cause apoptosis in the absence of Bid or Bim

D. Vaux, J. Heraud, A. Strasser, 2009, Cell Death and Differentiation.

The Shc-binding site of the betac subunit of the GM-CSF/IL-3/IL-5 receptors is a negative regulator of hematopoiesis.

C. Begley, Angel F. Lopez, H. Ramshaw, 2007, Blood.

Targeting of acute myeloid leukemia in vitro and in vivo with an anti-CD123 mAb engineered for optimal ADCC

H. Ramshaw, L. Fabri, A. Roberts, 2014, Leukemia.

Recombinant human interleukin-3 and granulocyte-macrophage colony-stimulating factor show common biological effects and binding characteristics on human monocytes.

M. Vadas, L. To, M. Elliott, 1989, Blood.

The receptor for interleukin 3 is selectively induced in human endothelial cells by tumor necrosis factor alpha and potentiates interleukin 8 secretion and neutrophil transmigration.

J. Gamble, G. Goodall, M. Vadas, 1993, Proceedings of the National Academy of Sciences of the United States of America.

Site-specific serine phosphorylation of the IL-3 receptor is required for hemopoietic cell survival.

M. Dottore, M. Berndt, B. McClure, 2000, Molecular cell.

Structure of the activation domain of the GM-CSF/IL-3/IL-5 receptor common beta-chain bound to an antagonist.

J. Rossjohn, M. Parker, W. McKinstry, 2000, Blood.

Specific human granulocyte-macrophage colony-stimulating factor antagonists.

M. F. Shannon, M. Vadas, M. Dottore, 1994, Proceedings of the National Academy of Sciences of the United States of America.

IL-3 and granulocyte-macrophage colony-stimulating factor stimulate two distinct phases of adhesion in human monocytes.

J. Gamble, M. Vadas, M. Elliott, 1990, Journal of immunology.

Blocking cytokine signaling along with intense Bcr-Abl kinase inhibition induces apoptosis in primary CML progenitors

J. Melo, R. D'Andrea, Angel F. Lopez, 2010, Leukemia.

Reciprocal inhibition of binding between interleukin 3 and granulocyte-macrophage colony-stimulating factor to human eosinophils.

M. Vadas, S. Clark, D. Gillis, 1989, Proceedings of the National Academy of Sciences of the United States of America.

The GM-CSF analogue E21R induces apoptosis of normal and activated eosinophils.

P. Iversen, A. Kay, S. Ying, 1997, American journal of respiratory and critical care medicine.

Granulocyte-macrophage colony-stimulating factor augments phagocytosis of Mycobacterium avium complex by human immunodeficiency virus type 1-infected monocytes/macrophages in vitro and in vivo.

K. Kedzierska, J. Mak, M. Rainbird, 2000, The Journal of infectious diseases.

Specific binding of human interleukin-3 and granulocyte-macrophage colony-stimulating factor to human basophils.

A. B. Lyons, M. Vadas, L. To, 1990, The Journal of allergy and clinical immunology.

Crucial Role of the Residue R280 at the F′–G′ Loop of the Human Granulocyte/Macrophage Colony-stimulating Factor Receptor α Chain for Ligand Recognition

A. Haman, T. Hoang, S. Clark, 1997, The Journal of experimental medicine.

Apoptosis of hemopoietic cells by the human granulocyte-macrophage colony-stimulating factor mutant E21R.

P. Iversen, L. To, A. Lopez, 1996, Proceedings of the National Academy of Sciences of the United States of America.