S. Thompson

发表

Bioisosteric determinants for subtype selectivity of ligands for heteromeric GABA(A) receptors.

J. Kehler, P. Krogsgaard‐Larsen, M. Mortensen, 2001, Bioorganic & medicinal chemistry letters.

Antagonism of human CC-chemokine receptor 4 can be achieved through three distinct binding sites on the receptor

S. Hodgson, D. Hall, R. Slack, 2013, Pharmacology research & perspectives.

Synthesis and biological evaluation of 3-heterocyclyl-7,8,9,10-tetrahydro-(7,10-ethano)-1,2,4-triazolo[3,4-a]phthalazines and analogues as subtype-selective inverse agonists for the GABA(A)alpha5 benzodiazepine binding site.

G. Dawson, R. Mckernan, A. Pike, 2004, Journal of medicinal chemistry.

Allosteric modulators affect the efficacy of partial agonists for recombinant GABAA receptors

G. Maksay, K. Wafford, S. Thompson, 2000, British journal of pharmacology.

2,5-Dihydropyrazolo[4,3-c]pyridin-3-ones: functionally selective benzodiazepine binding site ligands on the GABAA receptor.

Karen S. Curley, R. Mckernan, J. Atack, 2004, Bioorganic & medicinal chemistry letters.

Mechanism of action of general anaesthetics--new information from molecular pharmacology.

K. Wafford, S. Thompson, K. Wafford, 2001, Current opinion in pharmacology.

3-Phenyl-6-(2-pyridyl)methyloxy-1,2,4-triazolo[3,4-a]phthalazines and Analogues: High-Affinity γ-Aminobutyric Acid-A Benzodiazepine Receptor Ligands with α2, α3, and α5-Subtype Binding Selectivity over α1

G. Dawson, P. Leeson, R. Mckernan, 2004 .

3-phenyl-6-(2-pyridyl)methyloxy-1,2,4-triazolo[3,4-a]phthalazines and analogues: high-affinity gamma-aminobutyric acid-A benzodiazepine receptor ligands with alpha 2, alpha 3, and alpha 5-subtype binding selectivity over alpha 1.

G. Dawson, P. Leeson, R. Mckernan, 2004, Journal of medicinal chemistry.

Discovery of functionally selective 7,8,9,10-tetrahydro-7,10-ethano-1,2,4-triazolo[3,4-a]phthalazines as GABA A receptor agonists at the alpha3 subunit.

R. Mckernan, J. Atack, K. Wafford, 2005, Journal of medicinal chemistry.

Tracazolate Reveals a Novel Type of Allosteric Interaction with Recombinant γ-Aminobutyric AcidA Receptors

P. Whiting, K. Wafford, Keith A. Wafford, 2002 .

Effect of the TRPV1 antagonist SB‐705498 on the nasal parasympathetic reflex response in the ovalbumin sensitized guinea pig

A. Busza, D. Coe, K. Biggadike, 2013, British journal of pharmacology.

Functional characterization of human gamma-aminobutyric acidA receptors containing the alpha 4 subunit.

J. Sikela, P. Whiting, K. Wafford, 1996, Molecular pharmacology.

Differences in agonist/antagonist binding affinity and receptor transduction using recombinant human gamma-aminobutyric acid type A receptors.

R. Mckernan, P. Krogsgaard‐Larsen, B. Ebert, 1997, Molecular pharmacology.

Evidence for an enhancement of excitatory transmission in adult CNS by Wnt signaling pathway modulation

G. Mcallister, V. Beaumont, F. Choudhry, 2007, Molecular and Cellular Neuroscience.

Evidence for a Significant Role of α3-Containing GABAA Receptors in Mediating the Anxiolytic Effects of Benzodiazepines

G. Dawson, R. Dias, S. Tye, 2005, The Journal of Neuroscience.

Residues in transmembrane domains I and II determine gamma-aminobutyric acid type AA receptor subtype-selective antagonism by furosemide.

P. Whiting, K. Wafford, G. Marshall, 1999, Molecular pharmacology.

Barbiturate interactions at the human GABAA receptor: dependence on receptor subunit combination

P. Whiting, K. Wafford, S. Thompson, 1996, British journal of pharmacology.

Salicylidene salicylhydrazide, a selective inhibitor of β1‐containing GABAA receptors

C. Adkins, I. Collins, P. Whiting, 2004, British journal of pharmacology.

Key Amino Acids in the γ Subunit of the γ-Aminobutyric AcidA Receptor that Determine Ligand Binding and Modulation at the Benzodiazepine Site

P. Whiting, K. Wafford, P. Wingrove, 1997 .

Activity of chlormethiazole at human recombinant GABAA and NMDA receptors

P. Whiting, K. Wafford, S. Thompson, 2003, British journal of pharmacology.

Mutation at the putative GABAA ion‐channel gate reveals changes in allosteric modulation

P. Whiting, K. Wafford, P. Wingrove, 1999, British journal of pharmacology.

Functional characteristics of recombinant human GABAA receptors containing the ϵ-subunit

P. Whiting, T. Bonnert, K. Wafford, 1998 .

Overexpression of the GABAA receptor ε subunit results in insensitivity to anaesthetics

P. Whiting, T. Bonnert, K. Wafford, 2002, Neuropharmacology.

Expression and pharmacology of human GABAA receptors containing γ3 subunits

P. Whiting, S. Thompson, K. Wafford, 1995 .

Key amino acids in the gamma subunit of the gamma-aminobutyric acidA receptor that determine ligand binding and modulation at the benzodiazepine site.

P. Whiting, K. Wafford, P. Wingrove, 1997, Molecular pharmacology.

Tracazolate reveals a novel type of allosteric interaction with recombinant gamma-aminobutyric acid(A) receptors.

P. Whiting, K. Wafford, L. Connelly, 2002, Molecular pharmacology.