P. Chambon

发表

Simultaneous rapid chemical synthesis of over one hundred oligonucleotides on a microscale

M. Wintzerith, T. Grundström, H. Matthes, 1984, The EMBO journal.

The coactivator TIF2 contains three nuclear receptor‐binding motifs and mediates transactivation through CBP binding‐dependent and ‐independent pathways

H. Gronemeyer, J. Voegel, V. Vivat, 1998, The EMBO journal.

Interaction with members of the heterochromatin protein 1 (HP1) family and histone deacetylation are differentially involved in transcriptional silencing by members of the TIF1 family

R. Losson, A. Gansmuller, M. Oulad-Abdelghani, 1999, The EMBO journal.

Notch signaling is a direct determinant of keratinocyte growth arrest and entry into differentiation

Freddy Radtke, Daniel Metzger, Michel Aguet, 2001, The EMBO journal.

Differential ligand‐dependent interactions between the AF‐2 activating domain of nuclear receptors and the putative transcriptional intermediary factors mSUG1 and TIF1.

P. Chambon, R. Losson, H. Gronemeyer, 1996, The EMBO journal.

hTAF(II)68, a novel RNA/ssDNA‐binding protein with homology to the pro‐oncoproteins TLS/FUS and EWS is associated with both TFIID and RNA polymerase II.

P. Chambon, D. J. Heard, L. Tora, 1996, The EMBO journal.

Structure, localization and transcriptional properties of two classes of retinoic acid receptor alpha fusion proteins in acute promyelocytic leukemia (APL): structural similarities with a new family of oncoproteins.

P. Chambon, R. Berger, M. Lanotte, 1992, The EMBO journal.

A possible involvement of TIF1 alpha and TIF1 beta in the epigenetic control of transcription by nuclear receptors.

F. Jeanmougin, P. Chambon, R. Losson, 1996, The EMBO journal.

Role of the two activating domains of the oestrogen receptor in the cell‐type and promoter‐context dependent agonistic activity of the anti‐oestrogen 4‐hydroxytamoxifen.

P. Chambon, D. Metzger, M. Berry, 1990, The EMBO journal.

TIF2, a 160 kDa transcriptional mediator for the ligand‐dependent activation function AF‐2 of nuclear receptors.

P. Chambon, H. Gronemeyer, J. Voegel, 1996, The EMBO journal.

Transcriptional enhancer factor (TEF)‐1 and its cell‐specific co‐activator activate human papillomavirus‐16 E6 and E7 oncogene transcription in keratinocytes and cervical carcinoma cells.

P. Chambon, L. Turek, T. Cripe, 1992, The EMBO journal.

The N‐terminal part of TIF1, a putative mediator of the ligand‐dependent activation function (AF‐2) of nuclear receptors, is fused to B‐raf in the oncogenic protein T18.

P. Chambon, R. Losson, H. Gronemeyer, 1995, The EMBO journal.

RAR‐specific agonist/antagonists which dissociate transactivation and AP1 transrepression inhibit anchorage‐independent cell proliferation.

P. Chambon, J. Starrett, H. Gronemeyer, 1995, The EMBO journal.

The acidic transcriptional activator GAL‐VP16 acts on preformed template‐committed complexes.

P. Chambon, J. Wu, Y. Lutz, 1992, The EMBO journal.

The N‐terminal DNA‐binding ‘zinc finger’ of the oestrogen and glucocorticoid receptors determines target gene specificity.

P. Chambon, S. Green, W. Wahli, 1988, The EMBO journal.

The cloned human oestrogen receptor contains a mutation which alters its hormone binding properties.

P. Chambon, D. Metzger, L. Tora, 1989, The EMBO journal.

PMLRAR homodimers: distinct DNA binding properties and heteromeric interactions with RXR.

P. Chambon, P. Kastner, Y. Lutz, 1993, The EMBO journal.

RARs and RXRs: evidence for two autonomous transactivation functions (AF‐1 and AF‐2) and heterodimerization in vivo.

P. Chambon, H. Nakshatri, S. Friant, 1993, The EMBO journal.

One cell‐specific and three ubiquitous nuclear proteins bind in vitro to overlapping motifs in the domain B1 of the SV40 enhancer.

M. Vigneron, P. Chambon, M. Macchi, 1987, The EMBO journal.

Dimerization interfaces formed between the DNA binding domains determine the cooperative binding of RXR/RAR and RXR/TR heterodimers to DR5 and DR4 elements.

P. Chambon, X. Shen, H. Gronemeyer, 1994, The EMBO journal.

The dimerization interfaces formed between the DNA binding domains of RXR, RAR and TR determine the binding specificity and polarity of the full‐length receptors to direct repeats.

P. Chambon, H. Gronemeyer, C. Zechel, 1994, The EMBO journal.

Distinct TFIID complexes mediate the effect of different transcriptional activators.

P. Chambon, L. Tora, J. Wu, 1993, The EMBO journal.

The N‐terminal domain of the human TATA‐binding protein plays a role in transcription from TATA‐containing RNA polymerase II and III promoters.

P. Chambon, X. Jacq, D. Eberhard, 1994, The EMBO journal.

Activation function 2 (AF‐2) of retinoic acid receptor and 9‐cis retinoic acid receptor: presence of a conserved autonomous constitutive activating domain and influence of the nature of the response element on AF‐2 activity.

P. Chambon, R. Losson, B. Roy, 1994, The EMBO journal.

The putative nuclear receptor mediator TIF1alpha is tightly associated with euchromatin.

J. Vonesch, P. Chambon, R. Losson, 1999, Journal of cell science.