X. Zhuang

发表

An immunodominant NP105–113-B*07:02 cytotoxic T cell response controls viral replication and is associated with less severe COVID-19 disease

Calliope A. Dendrou, P. Sopp, P. Klenerman, 2021, Nature immunology.

The CCCTC-binding factor CTCF represses hepatitis B virus enhancer I and regulates viral transcription

G. Giraud, J. McKeating, P. Balfe, 2020, bioRxiv.

Gut microbiota as prognosis markers for patients with HBV-related acute-on-chronic liver failure

zhi-liang gao, Chun-Yan Lei, Ling Lv, 2020, Gut microbes.

Optimization of the supercritical fluidized bed process for sirolimus coating and drug release.

Cuiping Jiang, Tiejun Lu, Tianhui Yuan, 2020, International journal of pharmaceutics.

Hypoxia‐Inducible Factor 1 Alpha–Mediated RelB/APOBEC3B Down‐regulation Allows Hepatitis B Virus Persistence

P. Schirmacher, M. Heikenwalder, J. McKeating, 2021, Hepatology.

A dual role for SAMHD1 in regulating HBV cccDNA and RT-dependent particle genesis

Joanna L. Parish, J. McKeating, J. Rehwinkel, 2019, Life Science Alliance.

Circadian regulation of human immunodeficiency virus type 1 replication

P. Borrow, J. McKeating, Anna E. Kliszczak, 2022, bioRxiv.

Time-of-Day Variation in SARS-CoV-2 RNA Levels during the Second Wave of COVID-19

J. McKeating, D. Eyre, P. Balfe, 2022, Viruses.

Characterization of excipients to improve pharmaceutical properties of sirolimus in the supercritical anti-solvent fluidized process.

Xiubing Zhang, Fucheng Ge, Zhenwen Qiu, 2021, International journal of pharmaceutics.

Clocks, Viruses, and Immunity: Lessons for the COVID-19 Pandemic

J. McKeating, L. Ince, Shaon Sengupta, 2021, Journal of biological rhythms.

An immunodominant NP105–113-B*07:02 cytotoxic T cell response controls viral replication and is associated with less severe COVID-19 disease

P. Sopp, P. Klenerman, N. Ashley, 2021, Nature Immunology.

Hypoxic microenvironment shapes HIV-1 replication and latency

P. Borrow, M. Ashcroft, J. McKeating, 2020, Communications Biology.

The circadian clock components BMAL1 and REV-ERBα regulate flavivirus replication

Wai Hoong Chang, A. Loudon, P. Simmonds, 2019, Nature Communications.

Absolute quantitation of individual SARS-CoV-2 RNA molecules: a new paradigm for infection dynamics and variant differences

Alfredo Castello, J. McKeating, M. Thompson, 2021, bioRxiv.

Glucose and glutamine availability regulate HepG2 transcriptional responses to low oxygen

Chun-Xiao Song, J. McKeating, Alvina G. Lai, 2018, Wellcome open research.

The circadian clock component BMAL1 regulates SARS-CoV-2 entry and replication in lung epithelial cells

J. McKeating, Senko Tsukuda, C. Schuster, 2021, iScience.

Hypoxia inducible factors regulate infectious SARS-CoV-2, epithelial damage and respiratory symptoms in a hamster COVID-19 model

J. McKeating, F. Issa, M. Carroll, 2022, bioRxiv.

The role of circadian clock pathways in viral replication

Rachel S. Edgar, J. McKeating, X. Zhuang, 2022, Seminars in Immunopathology.

Synchronised infection identifies early rate-limiting steps in the hepatitis B virus life cycle

J. McKeating, U. Protzer, S. Roessler, 2020, Cellular microbiology.

Hypoxia inducible factors regulate hepatitis B virus replication by activating the basal core promoter

M. Weekes, M. Heikenwalder, E. Hammond, 2021, Journal of hepatology.

Absolute quantitation of individual SARS-CoV-2 RNA molecules provides a new paradigm for infection dynamics and variant differences

Alfredo Castello, J. McKeating, M. Thompson, 2022, eLife.

Cabazitaxel liposomes with aptamer modification enhance tumor-targeting efficacy in nude mice

Yuzhu Cheng, Z. Zhang, Yubin Zhou, 2018, Molecular medicine reports.

Circadian regulation of SARS-CoV-2 infection in lung epithelial cells

J. McKeating, Senko Tsukuda, C. Schuster, 2021, bioRxiv.

Hypoxic and pharmacological activation of HIF inhibits SARS-CoV-2 infection of lung epithelial cells

Alfredo Castello, P. Ratcliffe, J. McKeating, 2020, Cell Reports.

COVID-19, circadian rhythms and sleep: from virology to chronobiology

Sharlene Ting, Zulian Liu, X. Zhuang, 2021, Interface Focus.

Interplay between circadian clock and viral infection

J. McKeating, Alvina G. Lai, S. B. Rambhatla, 2017, Journal of Molecular Medicine.

Synchronized infection identifies early rate-limiting steps in the hepatitis B virus life cycle

J. McKeating, U. Protzer, J. Wettengel, 2020, bioRxiv.

The circadian clock components BMAL1 and REV-ERBα regulate flavivirus replication

Wai Hoong Chang, A. Loudon, P. Simmonds, 2019, Nature Communications.

Circadian control of hepatitis B virus replication

D. Ray, M. Iqbal, J. McKeating, 2021, Nature Communications.

The Circadian Clock and Viral Infections

J. McKeating, Helene Borrmann, X. Zhuang, 2020, Journal of biological rhythms.

HLA-E–restricted SARS-CoV-2–specific T cells from convalescent COVID-19 patients suppress virus replication despite HLA class Ia down-regulation

P. Klenerman, A. McMichael, P. Borrow, 2023, Science Immunology.

Pharmacological activation of the circadian component REV-ERB inhibits HIV-1 replication

P. Borrow, J. McKeating, P. Balfe, 2020, Scientific Reports.

Glucose and glutamine availability regulate HepG2 transcriptional responses to low oxygen

Jianzhao Liu, Chun-Xiao Song, J. McKeating, 2018, Wellcome open research.

Daytime variation in hepatitis C virus replication kinetics following liver transplant

J. McKeating, Alvina G. Lai, P. Balfe, 2018, Wellcome open research.

Molecular components of the circadian clock regulate HIV-1 replication

P. Borrow, J. McKeating, Anna E. Kliszczak, 2023, iScience.

The circadian clock components BMAL1 and REV-ERB regulate flavivirus replication

Wai Hoong Chang, Alvina G. Lai, T. Baumert, 2019 .