Paul T. Martin

J. Mendell, D. Boue, Paul T. Martin, 2006, Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society.

O-fucosylation of muscle agrin determines its ability to cluster acetylcholine receptors

P. Stanley, B. Kaspar, S. Shi, 2008, Molecular and Cellular Neuroscience.

Dystroglycan glycosylation and its role in matrix binding in skeletal muscle.

Paul T. Martin, 2003, Glycobiology.

Deletion of Pofut1 in Mouse Skeletal Myofibers Induces Muscle Aging-Related Phenotypes in cis and in trans

P. White, Ying Jia, Rui Xu, 2017, Molecular and Cellular Biology.

Muscular dystrophy with truncated dystrophin in a family of Japanese Spitz dogs

E. Engvall, J. Callanan, Ling T Guo, 2004, Journal of the Neurological Sciences.

rAAVrh74.MCK.GALGT2 Protects against Loss of Hemodynamic Function in the Aging mdx Mouse Heart.

Ying Jia, Paul T Martin, Rui Xu, 2019, Molecular therapy : the journal of the American Society of Gene Therapy.

Mice lacking dystrophin or alpha sarcoglycan spontaneously develop embryonal rhabdomyosarcoma with cancer-associated p53 mutations and alternatively spliced or mutant Mdm2 transcripts.

Karen S. Fernández, Laura T Martin, S. Hammond, 2010, The American journal of pathology.

A Human-Specific Deletion in Mouse Cmah Increases Disease Severity in the mdx Model of Duchenne Muscular Dystrophy

A. Varki, Ying Xu, J. Yoon, 2010, Science Translational Medicine.

Kumaran Chandrasekharan the mdx Model of Duchenne Muscular Dystrophy Increases Disease Severity in Cmah A Human-Specific Deletion in Mouse

A. Varki, Ying Xu, J. Yoon, 2010 .

Inhibition of dystroglycan cleavage causes muscular dystrophy in transgenic mice

K. Hoyte, B. Xia, A. Kammesheidt, 2003, Neuromuscular Disorders.

Defective Glycosylation of Dystroglycan in Muscular Dystrophy and Cancer

F. Montanaro, Paul T. Martin, 2011 .

Induction of T-Cell Infiltration and Programmed Death Ligand 2 Expression by Adeno-Associated Virus in Rhesus Macaque Skeletal Muscle and Modulation by Prednisone.

L. Rodino‐Klapac, L. Chicoine, Guohong Shao, 2017, Human gene therapy.

Distribution of ten laminin chains in dystrophic and regenerating muscles

J. Sanes, A. Pestronk, A. Connolly, 1999, Neuromuscular Disorders.

Vascular delivery of rAAVrh74.MCK.GALGT2 to the gastrocnemius muscle of the rhesus macaque stimulates the expression of dystrophin and laminin α2 surrogates.

J. Mendell, C. Walker, K. Clark, 2014, Molecular therapy : the journal of the American Society of Gene Therapy.

Mechanisms of Disease: congenital muscular dystrophies—glycosylation takes center stage

Paul T. Martin, 2006, Nature Clinical Practice Neurology.

The dystroglycanopathies: the new disorders of O-linked glycosylation.

Paul T Martin, Paul T. Martin, 2005, Seminars in pediatric neurology.

Glycobiology of neuromuscular disorders.

H. Freeze, Paul T. Martin, 2003, Glycobiology.

Role of extracellular matrix proteins and their receptors in the development of the vertebrate neuromuscular junction

N. Singhal, Paul T. Martin, 2011, Developmental neurobiology.

Short-term treatment of golden retriever muscular dystrophy (GRMD) dogs with rAAVrh74.MHCK7.GALGT2 induces muscle glycosylation and utrophin expression but has no significant effect on muscle strength

P. Nghiem, J. Kornegay, S. M. Birch, 2021, PloS one.

Overexpression of Galgt2 reduces dystrophic pathology in the skeletal muscles of alpha sarcoglycan-deficient mice.

M. Camboni, Rui Xu, Paul T. Martin, 2009, The American journal of pathology.

Identification of peptides that specifically bind Aβ1–40 amyloid in vitro and amyloid plaques in Alzheimer's disease brain using phage display

C. Kang, Paul T. Martin, Vianney Jayasinha, 2003, Neurobiology of Disease.

Expansion of B4GALT7 linkeropathy phenotype to include perinatal lethal skeletal dysplasia

R. Wilson, D. Koboldt, K. McBride, 2019, European Journal of Human Genetics.

Glycobiology of the synapse.

Paul T Martin, Paul T. Martin, 2002, Glycobiology.

Loss of CMAH during Human Evolution Primed the Monocyte–Macrophage Lineage toward a More Inflammatory and Phagocytic State

V. Nizet, C. Glass, A. Varki, 2017, The Journal of Immunology.

Distinct contributions of Galgt1 and Galgt2 to carbohydrate expression and function at the mouse neuromuscular junction

Rui Xu, N. Singhal, Paul T. Martin, 2012, Molecular and Cellular Neuroscience.

Genetic defects in muscular dystrophy.

Paul T Martin, K. Chandrasekharan, Paul T. Martin, 2010, Methods in enzymology.

Identification of New Dystroglycan Complexes in Skeletal Muscle

K. Flanigan, J. Ervasti, F. Montanaro, 2013, PloS one.

Role of transcription factors in skeletal muscle and the potential for pharmacological manipulation.

Paul T. Martin, 2003, Current opinion in pharmacology.

The synaptic CT carbohydrate modulates binding and expression of extracellular matrix proteins in skeletal muscle: Partial dependence on utrophin

J. Yoon, K. Chandrasekharan, Rui Xu, 2009, Molecular and Cellular Neuroscience.

Glycobiology of the neuromuscular junction

Paul T. Martin, 2003, Journal of neurocytology.

Sarcospan-dependent Akt activation is required for utrophin expression and muscle regeneration

Jamie L. Marshall, J. Holmberg, Angela K. Peter, 2012, The Journal of cell biology.

Overexpression of the cytotoxic T cell GalNAc transferase in skeletal muscle inhibits muscular dystrophy in mdx mice

K. Hoyte, B. Xia, Paul T. Martin, 2002, Proceedings of the National Academy of Sciences of the United States of America.

Overexpression of the CT GalNAc transferase in skeletal muscle alters myofiber growth, neuromuscular structure, and laminin expression.

T. Deerinck, Mark Ellisman, K. Hoyte, 2002, Developmental biology.

Role for a synapse-specific carbohydrate in agrin-induced clustering of acetylcholine receptors

J. Sanes, Paul T. Martin, 1995, Neuron.

Micro-laminin gene therapy can function as an inhibitor of muscle disease in the dyW mouse model of MDC1A

D. Packer, Paul T. Martin, 2021, Molecular therapy. Methods & clinical development.

Defective Glycosylation and Muscular Dystrophies

Paul T. Martin, 2007 .

Modulation of Agrin Binding and Activity by the CT and Related Carbohydrate Antigens

B. Xia, Paul T Martin, Paul T. Martin, 2002, Molecular and Cellular Neuroscience.

N-Acetyllactosamine and the CT Carbohydrate Antigen Mediate Agrin-Dependent Activation of MuSK and Acetylcholine Receptor Clustering in Skeletal Muscle

A. Kammesheidt, Paul T Martin, N. Parkhomovskiy, 2000, Molecular and Cellular Neuroscience.

N-terminal α Dystroglycan (αDG-N): A Potential Serum Biomarker for Duchenne Muscular Dystrophy.

K. Flanigan, Guohong Shao, K. Crowe, 2016, Journal of neuromuscular diseases.

B4GALNT2 (GALGT2) Gene Therapy Reduces Skeletal Muscle Pathology in the FKRP P448L Mouse Model of Limb Girdle Muscular Dystrophy 2I.

Rui Xu, P. Thomas, Paul T. Martin, 2016, The American journal of pathology.

Overexpression of the CT GalNAc transferase inhibits muscular dystrophy in a cleavage-resistant dystroglycan mutant mouse.

K. Hoyte, B. Xia, Paul T. Martin, 2003, Biochemical and biophysical research communications.

Altered expression of natively glycosylated α dystroglycan in pediatric solid tumors

Laura T Martin, E. Dosunmu, Paul T. Martin, 2007 .

Transgenic overexpression of dystroglycan does not inhibit muscular dystrophy in mdx mice.

K. Hoyte, B. Xia, Paul T. Martin, 2004, The American journal of pathology.

Soluble Heparin Binding Epidermal Growth Factor-Like Growth Factor Is a Regulator of GALGT2 Expression and GALGT2-Dependent Muscle and Neuromuscular Phenotypes

Rui Xu, Paul T. Martin, M. Cramer, 2019, Molecular and Cellular Biology.

Induction of a regenerative microenvironment in skeletal muscle is sufficient to induce embryonal rhabdomyosarcoma in p53‐deficient mice

S. Hammond, Paul T Martin, M. Camboni, 2012, The Journal of pathology.

Overexpression of Galgt2 in skeletal muscle prevents injury resulting from eccentric contractions in both mdx and wild-type mice.

J. Mendell, K. Clark, L. Rodino‐Klapac, 2009, American journal of physiology. Cell physiology.

Overexpression of Galgt 2 in skeletal muscle prevents injury resulting from eccentric contractions in both mdx and wild-type mice

J. Mendell, K. Clark, L. Rodino‐Klapac, 2009 .

Overexpression of the cytotoxic T cell (CT) carbohydrate inhibits muscular dystrophy in the dyW mouse model of congenital muscular dystrophy 1A.

J. Yoon, K. Chandrasekharan, M. Camboni, 2007, The American journal of pathology.

Serum Antibodies to N-Glycolylneuraminic Acid Are Elevated in Duchenne Muscular Dystrophy and Correlate with Increased Disease Pathology in Cmah-/-mdx Mice.

A. Varki, Sandra Díaz, Hai Yu, 2021, The American journal of pathology.

A Comparative Study of N-glycolylneuraminic Acid (Neu5Gc) and Cytotoxic T Cell (CT) Carbohydrate Expression in Normal and Dystrophin-Deficient Dog and Human Skeletal Muscle

K. Flanigan, A. Varki, J. Kornegay, 2014, PloS one.

N-Glycolylneuraminic acid deficiency worsens cardiac and skeletal muscle pathophysiology in α-sarcoglycan-deficient mice.

A. Varki, Chiou-Miin Wang, P. Janssen, 2013, Glycobiology.

Synaptic Integrins in Developing, Adult, and Mutant Muscle: Selective Association of α1, α7A, and α7B Integrins with the Neuromuscular Junction

J. Sanes, R. Kramer, S. Kaufman, 1996 .

Mouse Model of Limb Girdle Muscular Dystrophy 2 I

Rui Xu, P. Thomas, Paul T. Martin, 2016 .

Congenital muscular dystrophies involving the O-mannose pathway.

Paul T Martin, Paul T. Martin, 2007, Current molecular medicine.

An Isolated Limb Infusion Method Allows for Broad Distribution of rAAVrh74.MCK.GALGT2 to Leg Skeletal Muscles in the Rhesus Macaque

K. Flanigan, J. Cheatham, L. Rodino‐Klapac, 2018, Molecular therapy. Methods & clinical development.

A genome-wide association analysis of loss of ambulation in dystrophinopathy patients suggests multiple candidate modifiers of disease severity

V. Vieland, R. Weiss, D. Dunn, 2021, European Journal of Human Genetics.

The carbohydrate CT1 is expressed in topographically fixed glomeruli in the mouse olfactory bulb

A. Mackay-Sim, J. Ekberg, K. Lineburg, 2011, Molecular and Cellular Neuroscience.

Long-term enhancement of skeletal muscle mass and strength by single gene administration of myostatin inhibitors

J. Mendell, D. Boue, B. Kaspar, 2008, Proceedings of the National Academy of Sciences.

Active and passive immunization strategies based on the SDPM1 peptide demonstrate pre-clinical efficacy in the APPswePSEN1dE9 mouse model for Alzheimer's disease

Chiou-Miin Wang, B. Kaspar, Carlos J. Miranda, 2014, Neurobiology of Disease.

Differential distribution of heparan sulfate glycoforms and elevated expression of heparan sulfate biosynthetic enzyme genes in the brain of mucopolysaccharidosis IIIB mice

T. V. van Kuppevelt, H. Fu, D. Mccarty, 2011, Metabolic Brain Disease.

Altered expression of natively glycosylated alpha dystroglycan in pediatric solid tumors.

Laura T Martin, E. Dosunmu, Paul T. Martin, 2007, Human pathology.

Immunization with the SDPM1 peptide lowers amyloid plaque burden and improves cognitive function in the APPswePSEN1(A246E) transgenic mouse model of Alzheimer's disease

Chiou-Miin Wang, M. Camboni, Chiou‐Miin Wang, 2010, Neurobiology of Disease.

Visualizing Muscle Sialic Acid Expression in the GNED207VTgGne-/- Cmah-/- Model of GNE Myopathy: A Comparison of Dietary and Gene Therapy Approaches.

I. Nishino, L. Rodino‐Klapac, S. Noguchi, 2021, Journal of neuromuscular diseases.

Distinct Structures and Functions of Related Pre- and Postsynaptic Carbohydrates at the Mammalian Neuromuscular Junction

J. Sanes, Paul T Martin, Leland J. C. Scott, 1999, Molecular and Cellular Neuroscience.

Tetracarbonylmolybdenum complexes of 2-(phenylazo)pyridine ligands. Correlations of molybdenum-95 chemical shifts with electronic, infrared, and electrochemical properties

W. Fairbrother, Paul T Martin, M. Ackermann, 1996 .

Vascular delivery of rAAVrh74.MCK.GALGT2 to the gastrocnemius muscle of the rhesus macaque stimulates the expression of dystrophin and laminin α2 surrogates.

J. Mendell, C. Walker, L. Chicoine, 2014, Molecular therapy : the journal of the American Society of Gene Therapy.