Huili Li

Discovery of novel small molecule induced selective degradation of the bromodomain and extra-terminal (BET) bromodomain protein BRD4 and BRD2 with cellular potencies.

T. Lu, Yadong Chen, Hongmei Li, 2019, Bioorganic & medicinal chemistry.

Discovery of Benzo[cd]indol-2(1H)-ones and Pyrrolo[4,3,2-de]quinolin-2(1H)-ones as Bromodomain and Extra-Terminal Domain (BET) Inhibitors with Selectivity for the First Bromodomain with Potential High Efficiency Against Acute Gouty Arthritis.

Yanmin Zhang, T. Lu, Yadong Chen, 2019, Journal of medicinal chemistry.

Discovery of a Bromodomain and Extra Terminal Domain (BET) Inhibitor with the Selectivity for the Second Bromodomain (BD2) and the Capacity for the Treatment of Inflammatory Diseases.

Yadong Chen, Jiapeng Zhu, Lingfeng Yin, 2023, Journal of medicinal chemistry.