Patricia J. Lee

发表

Salicylanilide inhibitors of Toxoplasma gondii.

C. Roberts, R. McLeod, W. Welsh, 2012, Journal of medicinal chemistry.

An Automated Method for the Assessment of Memory and Learning in Larval Zebrafish

Yuanzhang Li, B. Pybus, Chance M Carbaugh, 2022, bioRxiv.

EVALUATION OF AROMATIC 6-SUBSTITUTED THIENOPYRIMIDINES AS SCAFFOLDS AGAINST PARASITES THAT CAUSE TRYPANOSOMIASIS, LEISHMANIASIS, AND MALARIA.

Ana Rodriguez, R. Behera, Jessey Erath, 2015, MedChemComm.

Antiparasitic Lead Discovery: Toward Optimization of a Chemotype with Activity Against Multiple Protozoan Parasites

Ana Rodriguez, Jessey Erath, M. Pollastri, 2017, ACS medicinal chemistry letters.

Use of the NP-40 Detergent-Mediated Assay in Discovery of Inhibitors of (cid:1) -Hematin Crystallization (cid:1) †

D. Wright, Jacob D. Johnson, Rebecca D Sandlin, 2011 .

The synthesis, antimalarial activity and CoMFA analysis of novel aminoalkylated quercetin analogs.

V. Avery, Sandra Duffy, T. Hagen, 2015, Bioorganic & medicinal chemistry letters.

Nanoparticle formulations of decoquinate increase antimalarial efficacy against liver stage Plasmodium infections in mice.

Q. Zeng, Qigui Li, M. Hickman, 2014, Nanomedicine : nanotechnology, biology, and medicine.

3,5-bis(benzylidene)-4-piperidones and related N-acyl analogs: a novel cluster of antimalarials targeting the liver stage of Plasmodium falciparum.

J. Dimmock, M. Hickman, J. Alcorn, 2013, Bioorganic & medicinal chemistry.

Identification of “Preferred” Human Kinase Inhibitors for Sleeping Sickness Lead Discovery. Are Some Kinases Better than Others for Inhibitor Repurposing?

Ana Rodriguez, H. Xi, Gonzalo Colmenarejo, 2016, ACS infectious diseases.

Characterization of in vivo metabolites of WR319691, a novel compound with activity against Plasmodium falciparum

S. Norval, K. Read, Q. Zeng, 2011, European Journal of Drug Metabolism and Pharmacokinetics.

Cytochrome P450 2D-mediated metabolism is not necessary for tafenoquine and primaquine to eradicate the erythrocytic stages of Plasmodium berghei

D. Caridha, Jonathan Berman, Qigui Li, 2016, Malaria Journal.

Use of the NP-40 Detergent-Mediated Assay in Discovery of Inhibitors of β-Hematin Crystallization

D. Wright, Jacob D. Johnson, Rebecca D Sandlin, 2011, Antimicrobial Agents and Chemotherapy.

Assessment of Azithromycin in Combination with Other Antimalarial Drugs against Plasmodium falciparum In Vitro

W. Milhous, C. Knirsch, C. Ohrt, 2002, Antimicrobial Agents and Chemotherapy.

Targeting the fatty acid biosynthesis enzyme, beta-ketoacyl-acyl carrier protein synthase III (PfKASIII), in the identification of novel antimalarial agents.

S. Prigge, L. Gerena, N. Waters, 2009, Journal of medicinal chemistry.

Synthesis and biological evaluation of novel sulfonyl-naphthalene-1,4-diols as FabH inhibitors.

N. Waters, K. Reynolds, Kevin A Reynolds, 2008, Bioorganic & medicinal chemistry letters.

Assessment of the Worldwide Antimalarial Resistance Network Standardized Procedure for In Vitro Malaria Drug Sensitivity Testing Using SYBR Green Assay for Field Samples with Various Initial Parasitemia Levels

M. Hickman, E. Kamau, Jacob D. Johnson, 2016, Antimicrobial Agents and Chemotherapy.

Updating the modified Thompson test by using whole-body bioluminescence imaging to replace traditional efficacy testing in experimental models of murine malaria

D. Caridha, Qigui Li, M. Hickman, 2019, Malaria Journal.

Functional human IgA targets a conserved site on malaria sporozoites

Peter D. Crompton, I. Wilson, P. Sinnis, 2021, Science Translational Medicine.

Structure-activity relationships of 4-position diamine quinoline methanols as intermittent preventative treatment (IPT) against Plasmodium falciparum.

L. Gerena, D. Caridha, P. Wipf, 2011, Journal of medicinal chemistry.

Functional characterization of the acyl carrier protein (PfACP) and beta-ketoacyl ACP synthase III (PfKASIII) from Plasmodium falciparum.

M. Gardner, S. Shallom, S. Prigge, 2002, Molecular and biochemical parasitology.

Ketotifen is an antimalarial prodrug of norketotifen with blood schizonticidal and liver-stage efficacy

D. Caridha, Qigui Li, M. Hickman, 2012, European Journal of Drug Metabolism and Pharmacokinetics.

Repurposing human Aurora kinase inhibitors as leads for anti-protozoan drug discovery.

Ana Rodriguez, Jessey Erath, M. Pollastri, 2014, MedChemComm.

The use of a prodrug approach to minimize potential CNS exposure of next generation quinoline methanols while maintaining efficacy in in vivo animal models

D. Caridha, Q. Zeng, Qigui Li, 2014, European journal of drug metabolism and pharmacokinetics.

Updating the modified Thompson test by using whole-body bioluminescence imaging to replace traditional efficacy testing in experimental models of murine malaria

Diana Caridha, Mark Hickman, Lisa Xie, 2019, Malaria Journal.

Fatty Acid synthesis as a target for antimalarial drug discovery.

S. Prigge, N. Waters, Jeff Zhiqiang Lu, 2005, Combinatorial chemistry & high throughput screening.

Protozoan Parasite Growth Inhibitors Discovered by Cross-Screening Yield Potent Scaffolds for Lead Discovery

Ana Rodriguez, Jessey Erath, E. Amata, 2015, Journal of medicinal chemistry.

Lactococcus lactis fabH, Encoding β-Ketoacyl-Acyl Carrier Protein Synthase, Can Be Functionally Replaced by the Plasmodium falciparum Congener

S. Prigge, B. Bachmann, Jacob D. Johnson, 2010, Applied and Environmental Microbiology.

Lactococcus lactis fabH , Encoding (cid:1) -Ketoacyl-Acyl Carrier Protein Synthase, Can Be Functionally Replaced by the Plasmodium falciparum Congener (cid:1)

S. Prigge, B. Bachmann, Jacob D. Johnson, 2010 .