Susan E. Leed

发表

Salicylanilide inhibitors of Toxoplasma gondii.

C. Roberts, R. McLeod, W. Welsh, 2012, Journal of medicinal chemistry.

Series of Alkynyl-Substituted Thienopyrimidines as Inhibitors of Protozoan Parasite Proliferation.

Ana Rodriguez, R. Behera, Jessey Erath, 2018, ACS medicinal chemistry letters.

EVALUATION OF AROMATIC 6-SUBSTITUTED THIENOPYRIMIDINES AS SCAFFOLDS AGAINST PARASITES THAT CAUSE TRYPANOSOMIASIS, LEISHMANIASIS, AND MALARIA.

Ana Rodriguez, R. Behera, Jessey Erath, 2015, MedChemComm.

In Vivo Bioluminescent Monitoring of Parasites in BALB/c Mouse Models of Cutaneous Leishmaniasis Drug Discovery.

D. Caridha, Susan E. Leed, Alicia Cawlfield, 2020, Methods in molecular biology.

Antiparasitic Lead Discovery: Toward Optimization of a Chemotype with Activity Against Multiple Protozoan Parasites

Ana Rodriguez, Jessey Erath, M. Pollastri, 2017, ACS medicinal chemistry letters.

Use of the NP-40 Detergent-Mediated Assay in Discovery of Inhibitors of (cid:1) -Hematin Crystallization (cid:1) †

D. Wright, Jacob D. Johnson, Rebecca D Sandlin, 2011 .

Optimization of physicochemical properties for 4-anilinoquinazoline inhibitors of trypanosome proliferation.

Ana Rodriguez, Jessey Erath, M. Pollastri, 2017, European journal of medicinal chemistry.

3,5-bis(benzylidene)-4-piperidones and related N-acyl analogs: a novel cluster of antimalarials targeting the liver stage of Plasmodium falciparum.

J. Dimmock, M. Hickman, J. Alcorn, 2013, Bioorganic & medicinal chemistry.

Optimization of Physicochemical Properties for 4-Anilinoquinoline Inhibitors of Plasmodium falciparum Proliferation.

Lori Ferrins, M. Pollastri, R. Sciotti, 2018, ACS infectious diseases.

Novel benzoxaborole, nitroimidazole and aminopyrazoles with activity against experimental cutaneous leishmaniasis

V. Yardley, S. Croft, D. Caridha, 2019, International journal for parasitology. Drugs and drug resistance.

Modification of Triclosan Scaffold in Search of Improved Inhibitors for Enoyl‐Acyl Carrier Protein (ACP) Reductase in Toxoplasma gondii

D. Rice, S. Prigge, C. Roberts, 2013, ChemMedChem.

Identification of “Preferred” Human Kinase Inhibitors for Sleeping Sickness Lead Discovery. Are Some Kinases Better than Others for Inhibitor Repurposing?

Ana Rodriguez, H. Xi, Gonzalo Colmenarejo, 2016, ACS infectious diseases.

Discovery and Structural Optimization of Acridones as Broad-Spectrum Antimalarials.

John C. Tan, D. Caridha, Q. Zeng, 2019, Journal of medicinal chemistry.

Anilinoquinoline based inhibitors of trypanosomatid proliferation

Ana Rodriguez, Jessey Erath, Lori Ferrins, 2018, PLoS neglected tropical diseases.

Characterization of in vivo metabolites of WR319691, a novel compound with activity against Plasmodium falciparum

S. Norval, K. Read, Q. Zeng, 2011, European Journal of Drug Metabolism and Pharmacokinetics.

Use of the NP-40 Detergent-Mediated Assay in Discovery of Inhibitors of β-Hematin Crystallization

D. Wright, Jacob D. Johnson, Rebecca D Sandlin, 2011, Antimicrobial Agents and Chemotherapy.

Direct Comparison of the Efficacy and Safety of Oral Treatments with Oleylphosphocholine (OlPC) and Miltefosine in a Mouse Model of L. major Cutaneous Leishmaniasis

D. Caridha, M. Grogl, M. Hickman, 2014, PLoS neglected tropical diseases.

Antileishmanial Activity of Compounds Derived from the Medicines for Malaria Venture Open Access Box against Intracellular Leishmania major Amastigotes

M. Grogl, R. Paris, Philip Smith, 2016, The American journal of tropical medicine and hygiene.

Assessment of the Worldwide Antimalarial Resistance Network Standardized Procedure for In Vitro Malaria Drug Sensitivity Testing Using SYBR Green Assay for Field Samples with Various Initial Parasitemia Levels

M. Hickman, E. Kamau, Jacob D. Johnson, 2016, Antimicrobial Agents and Chemotherapy.

Updating the modified Thompson test by using whole-body bioluminescence imaging to replace traditional efficacy testing in experimental models of murine malaria

D. Caridha, Qigui Li, M. Hickman, 2019, Malaria Journal.

Novel N-Benzoyl-2-Hydroxybenzamide Disrupts Unique Parasite Secretory Pathway

D. Rice, S. Prigge, W. Witola, 2012, Antimicrobial Agents and Chemotherapy.

Structure-activity relationships of 4-position diamine quinoline methanols as intermittent preventative treatment (IPT) against Plasmodium falciparum.

L. Gerena, D. Caridha, P. Wipf, 2011, Journal of medicinal chemistry.

Design, synthesis, and biological activity of diaryl ether inhibitors of Toxoplasma gondii enoyl reductase.

D. Rice, S. Prigge, C. Roberts, 2013, Bioorganic & medicinal chemistry letters.

Lead Optimization of Second-Generation Acridones as Broad-Spectrum Antimalarials.

P. Rosenthal, K. Reynolds, D. Caridha, 2020, Journal of medicinal chemistry.

Use of Optical Imaging Technology in the Validation of a New, Rapid, Cost-Effective Drug Screen as Part of a Tiered In Vivo Screening Paradigm for Development of Drugs To Treat Cutaneous Leishmaniasis

D. Caridha, M. Grogl, M. Hickman, 2017, Antimicrobial Agents and Chemotherapy.

Scaffold and Parasite Hopping: Discovery of New Protozoal Proliferation Inhibitors.

R. F. Campbell, Ana Rodriguez, J. McKerrow, 2020, ACS medicinal chemistry letters.

Ketotifen is an antimalarial prodrug of norketotifen with blood schizonticidal and liver-stage efficacy

D. Caridha, Qigui Li, M. Hickman, 2012, European Journal of Drug Metabolism and Pharmacokinetics.

Repurposing human Aurora kinase inhibitors as leads for anti-protozoan drug discovery.

Ana Rodriguez, Jessey Erath, M. Pollastri, 2014, MedChemComm.

Updating the modified Thompson test by using whole-body bioluminescence imaging to replace traditional efficacy testing in experimental models of murine malaria

Diana Caridha, Mark Hickman, Lisa Xie, 2019, Malaria Journal.

Auranofin is an apoptosis-simulating agent with in vitro and in vivo anti-leishmanial activity.

J. Lazo, M. Hickman, David A. Close, 2014, ACS chemical biology.

Protozoan Parasite Growth Inhibitors Discovered by Cross-Screening Yield Potent Scaffolds for Lead Discovery

Ana Rodriguez, Jessey Erath, E. Amata, 2015, Journal of medicinal chemistry.

Modification of Triclosan Scaffold in Search of Improved Inhibitors for Enoyl‐Acyl Carrier Protein (ACP) Reductase in Toxoplasma gondii

D. Rice, S. Prigge, C. Roberts, 2013, ChemMedChem.

Development of a triclosan scaffold which allows for adaptations on both the A- and B-ring for transport peptides.

D. Rice, S. Prigge, R. McLeod, 2013, Bioorganic & medicinal chemistry letters.

Novel hydrazone compounds with broad-spectrum antiplasmodial activity and synergistic interactions with antimalarial drugs

Emilee E. Colón-Lorenzo, D. Fidock, J. Vega-Rodríguez, 2024, Antimicrobial agents and chemotherapy.