Young Eum Hyun

发表

GPCR Agonist-to-Antagonist Conversion: Enabling the Design of Nucleoside Functional Switches for the A2A Adenosine Receptor

R. Stevens, K. Jacobson, Sun Choi, 2022, Journal of medicinal chemistry.

Discovery and Structure-Activity Relationships of Novel Template, Truncated 1'-Homologated Adenosine Derivatives as Pure Dual PPARγ/δ Modulators.

Ji Won Kim, K. Jacobson, K. Kang, 2020, Journal of medicinal chemistry.

Stereoselective Synthesis of Anti‐Hepatitis B Drug, Entecavir, through Regio‐ and Stereoselective Epoxide Cleavage

L. Jeong, Yongseok Choi, H. Kim, 2017 .

Identification of 6′-β-fluoro-homoaristeromycin as a potent inhibitor of chikungunya virus replication

L. Jeong, M. V. van Hemert, T. Chang, 2019, European Journal of Medicinal Chemistry.

An efficient synthesis of fluoro-neplanocin A analogs using electrophilic fluorination and palladium-catalyzed dehydrosilylation

L. Jeong, M. Jang, H. Kim, 2019, Organic Chemistry Frontiers.

Synthesis of Enantiomerically Pure Pyrimidine Ribonucleosides Locked in the South Conformation.

L. Jeong, H. Kim, Gyudong Kim, 2022, Organic letters.

Design, Synthesis, and Biological Activity of l-1'-Homologated Adenosine Derivatives.

L. Jeong, M. Noh, Jung-Ae Kim, 2022, ACS medicinal chemistry letters.

Stereoselective Synthesis of (S)- and (N)-Cyclopropyl-Fused Carbocyclic Nucleosides Using Stereoselective Cyclopropanation.

L. Jeong, H. Kim, Young Eum Hyun, 2021, The Journal of organic chemistry.

An alternative and efficient synthesis of MLN4924, a selective NEDD8 inhibitor

L. Jeong, Jinha Yu, H. Kim, 2019, Organic Chemistry Frontiers.

Asymmetric Synthesis of Fluoro‐MLN4924 as a Selective NEDD8‐Activating Enzyme (NAE) Inhibitor

L. Jeong, P. Sahu, Jinha Yu, 2019, Asian Journal of Organic Chemistry.

Structure-Activity Relationships of Truncated 1'-Homologated Carbaadenosine Derivatives as New PPARγ/δ Ligands: A Study on Sugar Puckering Affecting Binding to PPARs.

Sun Choi, L. Jeong, J. Huh, 2023, Journal of medicinal chemistry.

Structure-Activity Relationship of Truncated 2,8-Disubstituted-Adenosine Derivatives as Dual A2A/A3 Adenosine Receptor Antagonists and Their Cancer Immunotherapeutic Activity.

K. Jacobson, Zhang-Guo Gao, L. Jeong, 2023, Journal of medicinal chemistry.