S. Crane

发表

A novel enantioselective synthetic route to omuralide analogues with the potential for species selectivity in proteasome inhibition.

E. Corey, S. Crane, 2001, Organic letters.

Synthesis and SAR of pyrimidine-based, non-nucleotide P2Y14 receptor antagonists.

R. Gordon, S. Kargman, J. Mancini, 2011, Bioorganic & medicinal chemistry letters.

SAR and optimization of thiazole analogs as potent stearoyl-CoA desaturase inhibitors.

R. Oballa, J. Guay, Sébastien Guiral, 2010, Bioorganic & medicinal chemistry letters.

Beta-substituted cyclohexanecarboxamide cathepsin K inhibitors: modification of the 1,2-disubstituted aromatic core.

C. Bayly, M. Percival, R. Oballa, 2007, Bioorganic & medicinal chemistry letters.

Efficient and metal Free synthesis of 2,3-disubstituted pyridopyrimidinones via ketenimine intermediates

Peng Liu, Z. Sui, Jean-François Chiasson, 2023, Tetrahedron.

A generally applicable method for assessing the electrophilicity and reactivity of diverse nitrile-containing compounds.

Jean-François Truchon, Christopher I Bayly, C. Bayly, 2007, Bioorganic & medicinal chemistry letters.

Discovery of MK-8718, an HIV Protease Inhibitor Containing a Novel Morpholine Aspartate Binding Group.

W. Shipe, H. Su, J. Gesell, 2016, ACS medicinal chemistry letters.

GEMINAL ACYLATION OF KETONES MEDIATED BY BORON TRICHLORIDE. AN IMPROVED METHOD FOR THE SYNTHESIS OF 4,4-DIMETHYL-1,3-CYCLOPENTANEDIONES

D. Burnell, S. Crane, 1998 .

The BF3·Et2O-Catalyzed Reaction of 1,2-Bis[(trimethylsilyl)oxy]cyclobutene and Analogues with Aromatic Ketones

D. Burnell, S. Crane, 1998 .

Geminal Acylation with Methyl-Substituted Analogues of 1,2-Bis[(trimethylsilyl)oxy]cyclobutene

D. Burnell, T. Jenkins, S. Crane, 1997 .

Geminal acylation of α-heterosubstituted cyclohexanones and their ketals

David O. Miller, D. Burnell, I. Pottie, 2010 .

Investigation of ketone warheads as alternatives to the nitrile for preparation of potent and selective cathepsin K inhibitors.

R. Oballa, Qingping Wang, F. Massé, 2009, Bioorganic & medicinal chemistry letters.

Identification of a nonbasic, nitrile-containing cathepsin K inhibitor (MK-1256) that is efficacious in a monkey model of osteoporosis.

C. Bayly, J. Falgueyret, M. Percival, 2008, Journal of Medicinal Chemistry.

Beta-substituted cyclohexanecarboxamide: a nonpeptidic framework for the design of potent inhibitors of cathepsin K.

J. R. Somoza, C. Bayly, J. Palmer, 2006, Journal of Medicinal Chemistry.

Bicyclic heteroaryl inhibitors of stearoyl-CoA desaturase: from systemic to liver-targeting inhibitors.

Lei Zhang, Serge Leger, Jean-Philippe Leclerc, 2011, Bioorganic & medicinal chemistry letters.

Biological activity and preclinical efficacy of azetidinyl pyridazines as potent systemically-distributed stearoyl-CoA desaturase inhibitors.

R. Oballa, R. Gordon, J. Guay, 2011, Bioorganic & medicinal chemistry letters.