A. Héroux

发表

J. Deragon, S. Blagden, C. Bousquet-Antonelli, 2015 .

Water networks contribute to enthalpy/entropy compensation in protein-ligand binding.

G. Whitesides, W. Sherman, A. Héroux, 2013, Journal of the American Chemical Society.

The origin of the hydrophobic effect in the molecular recognition of arylsulfonamides by carbonic anhydrase

P. Snyder, G. Whitesides, A. Héroux, 2011 .

Mechanism of the hydrophobic effect in the biomolecular recognition of arylsulfonamides by carbonic anhydrase

George M. Whitesides, Woody Sherman, Demetri T. Moustakas, 2011, Proceedings of the National Academy of Sciences.

Dual recognition of phosphoserine and phosphotyrosine in histone variant H2A.X by DNA damage response protein MCPH1

F. Couch, M. Yaffe, M. Rosenfeld, 2012, Proceedings of the National Academy of Sciences.

The Effect of Clade-Speciﬁc Sequence Polymorphisms on HIV-1 Protease Activity and Inhibitor Resistance Pathways (cid:1)

C. Schiffer, W. Sugiura, E. Nalivaika, 2010 .

BACTERIAL NADQ (COG4111) IS A NUDIX-LIKE, ATP-RESPONSIVE REGULATOR OF NAD BIOSYNTHESIS.

D. Rodionov, L. Sorci, N. Raffaelli, 2022, Journal of structural biology.

Mail-in crystallography program at Brookhaven National Laboratory's National Synchrotron Light Source.

Michael Becker, Alexei S Soares, Robert Sweet, 2006, Acta crystallographica. Section D, Biological crystallography.

Remote Access to the PXRR Macromolecular Crystallography Facilities at the NSLS

R. Sweet, A. Soares, J. Skinner, 2008 .

Acoustic Injectors for Drop-On-Demand Serial Femtosecond Crystallography.

A. Kuczewski, Diling Zhu, A. Cohen, 2016, Structure.

Structural, electrochemical, and spectroscopic properties of a class of dodecasubstituted iron porphyrins bearing four positive charges close to the metal

D. Mansuy, A. Héroux, M. Renner, 2007 .

Crystallography and AM1 and INDO/S calculations on electronic ground and excited singlet states of 2-[p-(dimethylamino)phenyl]-3,3-dimethyl-3H-indole: solvent effects on the absorption and fluorescence spectra

G. Durocher, M. Belletěte, N. Godbout, 1991 .

Electronic and molecular structure of 2-phenyl-3,3-dimethyl-3H-indole molecular fluorescence probe and the molecular structure of its dimer

G. Durocher, D. Gravel, M. Belletěte, 1993 .

Crystal structure of tricyclo-DNA: an unusual compensatory change of two adjacent backbone torsion angles.

Z. Wawrzak, M. Egli, D. Ittig, 2008, Chemical communications.

Structural reorganization triggered by charging of Lys residues in the hydrophobic interior of a protein.

Annie Heroux, J. Schlessman, B. García-Moreno, 2012, Structure.

Virtual Screening for UDP-Galactopyranose Mutase Ligands Identifies a New Class of Antimycobacterial Agents.

Nir London, Katrina T Forest, Brian K Shoichet, 2015, ACS chemical biology.

Substrate deformation in a hypoxanthine-guanine phosphoribosyltransferase ternary complex: the structural basis for catalysis.

A. Kuzin, D. Borhani, E. White, 2000, Structure.

Structural and biochemical characterization of Gun4 suggests a mechanism for its role in chlorophyll biosynthesis.

J. D. Reid, C. Hill, C. Hunter, 2005, Biochemistry.

Structural and Functional Studies on the Interaction of GspC and GspD in the Type II Secretion System

W. Hol, E. Pardon, J. Steyaert, 2011, PLoS pathogens.

Human γ-Glutamyl Transpeptidase 1

B. Mooers, Clyde A. Smith, S. Terzyan, 2015, The Journal of Biological Chemistry.

Novel Insights into Eukaryotic γ-Glutamyltranspeptidase 1 from the Crystal Structure of the Glutamate-bound Human Enzyme*

B. Mooers, M. Hanigan, Matthew B West, 2013, The Journal of Biological Chemistry.

Structure of the Membrane-tethering GRASP Domain Reveals a Unique PDZ Ligand Interaction That Mediates Golgi Biogenesis*

A. Linstedt, M. MacBeth, Steven T Truschel, 2011, The Journal of Biological Chemistry.

CD94-NKG2A recognition of human leukocyte antigen (HLA)-E bound to an HLA class I leader sequence

T. Beddoe, J. Rossjohn, M. Wilce, 2008, The Journal of experimental medicine.

A highly tilted binding mode by a self-reactive T cell receptor results in altered engagement of peptide and MHC

K. Wucherpfennig, E. Sundberg, J. Pyrdol, 2011, The Journal of experimental medicine.

Crystal structure of a CRISPR RNA–guided surveillance complex bound to a ssDNA target

S. Mulepati, S. Bailey, A. Héroux, 2014, Science.

Crystal structure of the β-finger domain of Prp8 reveals analogy to ribosomal proteins

Tao Xu, R. Zhao, Kui Yang, 2008, Proceedings of the National Academy of Sciences.

Crystal structure of the C‐terminal domain of splicing factor Prp8 carrying retinitis pigmentosa mutants

M. Guarnieri, R. Zhao, Kui Yang, 2007, Protein science : a publication of the Protein Society.

Structural analysis uncovers a role for redox in regulating FKBP13, an immunophilin of the chloroplast thylakoid lumen.

S. Luan, K. Swaminathan, B. Buchanan, 2004, Proceedings of the National Academy of Sciences of the United States of America.

PyXRF: Python-based X-ray fluorescence analysis package

Hanfei Yan, Wah-Keat Lee, Dantong Yu, 2017, Optical Engineering + Applications.

Interactions between Hofmeister anions and the binding pocket of a protein.

G. Whitesides, W. Sherman, Kyungtae Kang, 2015, Journal of the American Chemical Society.

Structural Models for Interactions between the 20S Proteasome and Its PAN/19S Activators*

K. Ferrell, C. Hill, D. Myszka, 2009, The Journal of Biological Chemistry.

Structure of the Shroom-Rho Kinase Complex Reveals a Binding Interface with Monomeric Shroom That Regulates Cell Morphology and Stimulates Kinase Activity*

Jenna K. Zalewski, Annie Heroux, Simone Heber, 2016, The Journal of Biological Chemistry.

Crystal structures of intermediates in the nitroalkane oxidase reaction.

P. F. Fitzpatrick, A. Héroux, A. Orville, 2009, Biochemistry.

Structure of a Highly Conserved Domain of Rock1 Required for Shroom-Mediated Regulation of Cell Morphology

Michael A. Trakselis, Robert J. Bauer, Jenna K. Zalewski, 2013, PloS one.

Structure of Shroom domain 2 reveals a three-segmented coiled-coil required for dimerization, Rock binding, and apical constriction

Michael A. Trakselis, Robert J. Bauer, Andrew P. VanDemark, 2012, Molecular biology of the cell.

Triosephosphate isomerase I170V alters catalytic site, enhances stability and induces pathology in a Drosophila model of TPI deficiency.

R. Wetzel, M. Palladino, B. Roland, 2015, Biochimica et biophysica acta.

Acoustic methods for high-throughput protein crystal mounting at next-generation macromolecular crystallographic beamlines.

Alexei S Soares, Anthony Kuczewski, Marc Allaire, 2013, Journal of synchrotron radiation.

Structural and Functional Analysis of the Spt16p N-terminal Domain Reveals Overlapping Roles of yFACT Subunits*

D. Stillman, T. Formosa, C. Hill, 2008, Journal of Biological Chemistry.

The Ubiquitin Binding Domain ZnF UBP Recognizes the C-Terminal Diglycine Motif of Unanchored Ubiquitin

Xiaodong Cheng, K. Wilkinson, J. Horton, 2006, Cell.

Potent D-peptide inhibitors of HIV-1 entry

Michael S. Kay, Andrew P. VanDemark, Annie Heroux, 2007, Proceedings of the National Academy of Sciences.

Telomere capping proteins are structurally related to RPA with an additional telomere-specific domain

R. Batey, D. Wuttke, V. Lundblad, 2009, Proceedings of the National Academy of Sciences.

Structural basis for Spt5-mediated recruitment of the Paf1 complex to chromatin

Adam D. Wier, A. Vandemark, M. Mayekar, 2013, Proceedings of the National Academy of Sciences.

The Histone Modification Domain of Paf1 Complex Subunit Rtf1 Directly Stimulates H2B Ubiquitylation through an Interaction with Rad6.

Adam D. Wier, B. Pugh, Vinesh Vinayachandran, 2016, Molecular cell.

Cdc73 Subunit of Paf1 Complex Contains C-terminal Ras-like Domain That Promotes Association of Paf1 Complex with Chromatin*

Christopher P. Davis, R. Gardner, C. G. Amrich, 2012, The Journal of Biological Chemistry.

Polymerization-defective fibrinogen variant gammaD364A binds knob "A" peptide mimic.

L. Betts, S. Lord, O. Gorkun, 2008, Biochemistry.

Cdc 73 Subunit of Paf 1 Complex Contains C-terminal Ras-like Domain That Promotes Association of Paf 1 Complex with Chromatin *

Christopher P. Davis, R. Gardner, C. G. Amrich, 2012 .

A novel copper-binding fold for the periplasmic copper resistance protein CusF.

M. McEvoy, C. Rensing, W. Montfort, 2005, Biochemistry.

Structure and mechanistic implications of a uroporphyrinogen III synthase-product complex.

C. Hill, J. Phillips, A. Héroux, 2008, Biochemistry.

Crystal structure of the Entamoeba histolytica RNA lariat debranching enzyme EhDbr1 reveals a catalytic Zn2+/Mn2+ heterobinucleation

A. Héroux, Elizabeth Ransey, E. Paredes, 2017, FEBS letters.

Structure of an actin-related subcomplex of the SWI/SNF chromatin remodeler

B. Cairns, M. Kasten, C. Hill, 2013, Proceedings of the National Academy of Sciences.

Autoregulation of the rsc4 tandem bromodomain by gcn5 acetylation.

B. Cairns, M. Kasten, C. Hill, 2007, Molecular cell.

Crystal Structure of the Chromodomain Helicase DNA-binding Protein 1 (Chd1) DNA-binding Domain in Complex with DNA*

G. Bowman, Amit Sharma, A. Héroux, 2011, The Journal of Biological Chemistry.

Structural Characterization of Alzheimer DNA Promoter Sequences from the Amyloid Precursor Gene in the Presence of Thioflavin T and Analogs

T. Doukov, B. Shivachev, R. Rusew, 2022, Crystals.

The structure of the yFACT Pob3-M domain, its interaction with the DNA replication factor RPA, and a potential role in nucleosome deposition.

T. Formosa, C. Hill, E. Ferris, 2006, Molecular cell.

Structure of the class IV adenylyl cyclase reveals a novel fold.

D. Gallagher, H. Robinson, N. Smith, 2006, Journal of molecular biology.

Coupling of Conformational Transitions in the N-terminal Domain of the 51-kDa FK506-binding Protein (FKBP51) Near Its Site of Interaction with the Steroid Receptor Proteins*

D. LeMaster, G. Hernández, Hongmin Li, 2015, The Journal of Biological Chemistry.

Abstract No. roul0025 Crystal Structure of the Unliganded form of the Recombination Mediator Protein uvsY

Hang Xu, S. Morrical, A. Héroux, 2002 .

Structural basis for recognition of S-adenosylhomocysteine by riboswitches.

Andrea L Edwards, R. Batey, A. Edwards, 2010, RNA.

Crystal Structure of the Lysine Riboswitch Regulatory mRNA Element*

R. Batey, R. Rambo, A. Héroux, 2008, Journal of Biological Chemistry.

Structure of Factor H-binding Protein B (FhbB) of the Periopathogen, Treponema denticola

D. Conrad, J. Bell, R. Marconi, 2012, The Journal of Biological Chemistry.

Atomic structures of human dihydrofolate reductase complexed with NADPH and two lipophilic antifolates at 1.09 a and 1.05 a resolution.

Anthony E Klon, A. Klon, D. Borhani, 2002, Journal of molecular biology.

Diamond X-ray Photodiode for White and Monochromatic SR beams.

J. Smedley, J. Keister, E. Muller, 2011, Nuclear instruments & methods in physics research. Section A, Accelerators, spectrometers, detectors and associated equipment.

Crystal structures of the Toxoplasma gondii hypoxanthine-guanine phosphoribosyltransferase-GMP and -IMP complexes: comparison of purine binding interactions with the XMP complex.

D. Borhani, E. White, L. Ross, 1999, Biochemistry.

Crystal structure and conformational flexibility of the unligated FK506-binding protein FKBP12.6

D. LeMaster, G. Hernández, Zhong Li, 2014, Acta crystallographica. Section D, Biological crystallography.

Molecular Basis of Phosphatidylinositol 4-Phosphate and ARF1 GTPase Recognition by the FAPP1 Pleckstrin Homology (PH) Domain*

Siddhartha Roy, T. Kutateladze, R. Stahelin, 2011, The Journal of Biological Chemistry.

Differential quantum tunneling contributions in nitroalkane oxidase catalyzed and the uncatalyzed proton transfer reaction

Jiali Gao, Annie Heroux, Jiali Gao, 2009, Proceedings of the National Academy of Sciences.

Transmission-mode diamond white-beam position monitor at NSLS.

M. Sullivan, M. Allaire, L. Berman, 2012, Journal of synchrotron radiation.

Biochemical and structural studies of yeast Vps4 oligomerization.

Annie Heroux, W. Sundquist, C. Hill, 2008, Journal of molecular biology.

Crystal Structure of the N-terminal Domain of the Group B Streptococcus Alpha C Protein*

D. Filman, L. Madoff, J. Hogle, 2005, Journal of Biological Chemistry.

Macromolecular crystallography beamline X25 at the NSLS

Robert M. Sweet, John M. Skinner, Lonny E. Berman, 2014, Journal of synchrotron radiation.

Structural and Genetic Studies Demonstrate Neurologic Dysfunction in Triosephosphate Isomerase Deficiency Is Associated with Impaired Synaptic Vesicle Dynamics

M. Palladino, B. Roland, A. Zeccola, 2016, PLoS genetics.

Crystal structure of Toxoplasma gondii hypoxanthine-guanine phosphoribosyltransferase with XMP, pyrophosphate, and two Mg(2+) ions bound: insights into the catalytic mechanism.

R. Davis, D. Borhani, E. White, 1999, Biochemistry.

The structure of Xis reveals the basis for filament formation and insight into DNA bending within a mycobacteriophage intasome.

Shweta Singh, C. G. Amrich, A. Vandemark, 2014, Journal of molecular biology.

Mechanistic and structural analyses of the roles of Arg409 and Asp402 in the reaction of the flavoprotein nitroalkane oxidase.

Patrick G. Shaw, A. Orville, M. Valley, 2008, Biochemistry.

R. Sweet, A. Orville, J. Skinner, 2011, Journal of synchrotron radiation.

The binding of benzoarylsulfonamide ligands to human carbonic anhydrase is insensitive to formal fluorination of the ligand.

G. Whitesides, W. Sherman, Dmitrij Rappoport, 2013, Angewandte Chemie.

First structure of full-length mammalian phenylalanine hydroxylase reveals the architecture of an autoinhibited tetramer

E. Parker, P. J. Cross, P. Loll, 2016, Proceedings of the National Academy of Sciences.

X-ray radiation induces deprotonation of the bilin chromophore in crystalline D. radiodurans phytochrome.

G. Schatz, R. Vierstra, A. Orville, 2015, Journal of the American Chemical Society.

Software tools for X-ray photon correlation and X-ray speckle visibility spectroscopy

Eric D. Dill, S. Wilkins, Yugang Zhang, 2016, 2016 New York Scientific Data Summit (NYSDS).

Preliminary crystallographic studies of the regulatory domain of response regulator YycF from an essential two-component signal transduction system.

L. Tang, Haiyan Zhao, A. Héroux, 2009, Acta crystallographica. Section F, Structural biology and crystallization communications.

Andrea J. Berman, J. Deragon, S. Blagden, 2015, Nucleic acids research.

Three-beam interference is a sensitive measure of the efficacy of macromolecular refinement techniques.

E. Weckert, R. Sweet, A. Soares, 2003, Acta crystallographica. Section D, Biological crystallography.

The 2/2 hemoglobin from the cyanobacterium Synechococcus sp. PCC 7002 with covalently attached heme: Comparison of X‐ray and NMR structures

J. Schlessman, J. Lecomte, B. Wenke, 2014, Proteins.

The Effect of Clade-Specific Sequence Polymorphisms on HIV-1 Protease Activity and Inhibitor Resistance Pathways

C. Schiffer, W. Sugiura, E. Nalivaika, 2010, Journal of Virology.

Crystal structures of glutathione- and inhibitor-bound human GGT1: critical interactions within the cysteinylglycine binding site.

Clyde A. Smith, S. Terzyan, M. Hanigan, 2020, The Journal of biological chemistry.

Crystal structures of glutathione- and inhibitor-bound human GGT1: critical interactions within the cysteinylglycine binding site

Clyde A. Smith, S. Terzyan, M. Hanigan, 2020, The Journal of biological chemistry.

The 1.75 Å resolution structure of fission protein Fis1 from Saccharomyces cerevisiae reveals elusive interactions of the autoinhibitory domain.

M. Bewley, J. Schlessman, V. Khangulov, 2011, Acta crystallographica. Section F, Structural biology and crystallization communications.

Improvement of the crystallizability and expression of an RNA crystallization chaperone.

Jing-Dong Ye, Priyadarshini Ravindran, A. Héroux, 2011, Journal of biochemistry.

Fluoroalkyl and alkyl chains have similar hydrophobicities in binding to the "hydrophobic wall" of carbonic anhydrase.

G. Whitesides, K. Mirica, J. Mecinović, 2011, Journal of the American Chemical Society.

Crystallization and phasing of alanine dehydrogenase from Archaeoglobus fulgidus.

D. Gallagher, H. Robinson, M. Holden, 2003, Acta crystallographica. Section D, Biological crystallography.

Two structures of a lambda Cro variant highlight dimer flexibility but disfavor major dimer distortions upon specific binding of cognate DNA.

M. Cordes, B. M. Hall, S. Roberts, 2008, Journal of molecular biology.