L. Wester

A kinase inhibitor screen reveals MEK1/2 as a novel therapeutic target to antagonize IGF1R-mediated antiestrogen resistance in ERα-positive luminal breast cancer.

W. V. van IJcken, J. Martens, B. van de Water, 2022, Biochemical pharmacology.

Epidermal growth factor receptor signalling in human breast cancer cells operates parallel to estrogen receptor α signalling and results in tamoxifen insensitive proliferation

Marja Moerkens, Yinghui Zhang, Lynn Wester, 2014, BMC Cancer.

Epidermal growth factor receptor signalling in human breast cancer cells operates parallel to estrogen receptor α signalling and results in tamoxifen insensitive proliferation

Marja Moerkens, Yinghui Zhang, B. van de Water, 2014, BMC Cancer.

IGF1R signaling drives antiestrogen resistance through PAK2/PIX activation in luminal breast cancer

M. Look, E. Berns, Jean C. A. Helmijr, 2018, Oncogene.

The N-Terminal DH-PH Domain of Trio Induces Cell Spreading and Migration by Regulating Lamellipodia Dynamics in a Rac1-Dependent Fashion

P. Hordijk, M. Hoogenboezem, J. V. van Buul, 2012, PloS one.

Serine phosphorylation of the RhoGEF Trio stabilizes endothelial cell-cell junctions

V. de Waard, J. V. van Buul, M. van den Biggelaar, 2023, Small GTPases.