Eamonn Reading

发表

Perturbed structural dynamics underlie inhibition and altered efflux of the multidrug resistance pump AcrB

Andy M. Lau, Andy M C Lau, P. Ruggerone, 2020, Nature Communications.

Perturbed structural dynamics underlie inhibition and altered specificity of the multidrug efflux pump AcrB

Andy M. Lau, Andy M C Lau, P. Ruggerone, 2020, bioRxiv.

Silver and Palladium Complexes Containing Ditopic N-Heterocyclic Carbene–Thione Ligands

Gareth R. Owen, M. Haddow, Eamonn Reading, 2012 .

Photoinitiated Polymerization-Induced Self-Assembly in the Presence of Surfactants Enables Membrane Protein Incorporation into Vesicles

Lewis D. Blackman, P. Booth, R. O’Reilly, 2018, Macromolecules.

Structure of a Designed Protein Cage that Self-Assembles into a Highly Porous Cube

Greg L. Hura, T. Yeates, J. Tainer, 2014, Nature chemistry.

Conformational restriction shapes the inhibition of a multidrug efflux adaptor protein

Jerry M. Parks, A. J. Higgins, M. Moniruzzaman, 2022, bioRxiv.

Structural mass spectrometry approaches to understand multidrug efflux systems

Dietmar Hammerschmid, Eamonn Reading, Dietmar Hammerschmid, 2022, Essays in biochemistry.

Structural Mass Spectrometry of Membrane Proteins within Their Native Lipid Environments.

Eamonn Reading, 2018, Chemistry.

Interrogating Membrane Protein Conformational Dynamics within Native Lipid Compositions.

P. Booth, Z. Hall, Z. Ahdash, 2017, Angewandte Chemie.

Elucidation of Drug Metabolite Structural Isomers Using Molecular Modeling Coupled with Ion Mobility Mass Spectrometry.

Jordi Munoz-Muriedas, Carol V Robinson, C. Robinson, 2016, Analytical chemistry.

Membrane proteins bind lipids selectively to modulate their structure and function

C. Robinson, E. Reading, A. Laganowsky, 2014, Nature.

Capturing Membrane Protein Ribosome Nascent Chain Complexes in a Native-like Environment for Co-translational Studies

P. Booth, Tim M Gemeinhardt, H. Findlay, 2020, Biochemistry.

Mass spectrometry of intact membrane protein complexes

Carol V Robinson, C. Robinson, A. Laganowsky, 2013, Nature Protocols.

Mass spectrometry reveals synergistic effects of nucleotides, lipids, and drugs binding to a multidrug resistance efflux pump

P. Biggin, C. Robinson, G. Chang, 2013, Proceedings of the National Academy of Sciences.

Structural dynamics in the evolution of SARS-CoV-2 spike glycoprotein

Richard T. Bradshaw, M. Malim, S. Gamblin, 2023, Nature Communications.

Quantifying the stabilizing effects of protein–ligand interactions in the gas phase

Carol V Robinson, Timothy M Allison, Idlir Liko, 2015, Nature Communications.

Native mass spectrometry goes more native: investigation of membrane protein complexes directly from SMALPs† †Electronic supplementary information (ESI) available: Experimental details, additional information on methods. See DOI: 10.1039/c8cc06284f

P. Booth, N. Morgner, I. Tascón, 2018, Chemical communications.

The Effect of Detergent, Temperature, and Lipid on the Oligomeric State of MscL Constructs: Insights from Mass Spectrometry.

D. Rees, C. Robinson, A. Laganowsky, 2015, Chemistry & biology.

The role of the detergent micelle in preserving the structure of membrane proteins in the gas phase.

Carol V Robinson, Timothy M Allison, Idlir Liko, 2015, Angewandte Chemie.

Structure formation during translocon-unassisted co-translational membrane protein folding

P. Booth, J. Heberle, K. Ataka, 2017, Scientific Reports.

Lipid binding attenuates channel closure of the outer membrane protein OmpF

Thomas D. Newport, C. Robinson, H. Bayley, 2018, Proceedings of the National Academy of Sciences.

Chromatographic Phospholipid Trapping for Automated H/D Exchange Mass Spectrometry of Membrane Protein–Lipid Assemblies

M. Morris, Laetitia Denbigh, Dietmar Hammerschmid, 2023, Analytical chemistry.

Direct protein-lipid interactions shape the conformational landscape of secondary transporters

Andy M. Lau, E. Tajkhorshid, P. Booth, 2018, Nature Communications.

Peptide-Based Approach to Inhibition of the Multidrug Resistance Efflux Pump AcrB.

C. Deber, T. Stone, Eamonn Reading, 2020, Biochemistry.

Mechanistic insight into the assembly of the HerA–NurA helicase–nuclease DNA end resection complex

Andy M. Lau, H. Urlaub, P. Booth, 2017, Nucleic acids research.

Cell-Free Synthesis Strategies to Probe Co-translational Folding of Proteins Within Lipid Membranes.

P. Booth, Eamonn Reading, Nicola J. Harris, 2022, Methods in molecular biology.

Structure formation during translocon-unassisted co-translational membrane protein folding

P. Booth, J. Heberle, K. Ataka, 2017, Scientific Reports.

TMEM106B is a receptor mediating ACE2-independent SARS-CoV-2 cell entry

F. Smet, E. Vanstreels, P. Maes, 2023, Cell.

TMEM106B is a receptor mediating ACE2-independent SARS-CoV-2 cell entry

E. Vanstreels, P. Maes, F. De Smet, 2023, Cell.