Xenia B. Searle

发表

A mixed Ca channel blocker, A-1264087, utilizes peripheral and spinal mechanisms to inhibit spinal nociceptive transmission in a rat model of neuropathic pain

A. Swensen, Lance Lee, M. Jarvis, 2013 .

Discovery and SAR of 4-Aminopyrrolidine-2-carboxylic Acid Correctors of CFTR for the Treatment of Cystic Fibrosis.

A. Bogdan, A. Swensen, Ashvani K. Singh, 2022, Bioorganic & medicinal chemistry letters.

3-Amino-2-hydroxyamides and related compounds as inhibitors of methionine aminopeptidase-2.

Scott A. Erickson, Jyoti R. Patel, Chang H. Park, 2004, Bioorganic & medicinal chemistry letters.

Uninjured Rats Dynamic Range Neurons in CFA-Treated and Selective TRPV1 Receptor Antagonist, on Wide Systemic and Site-Specific Effects of A-425619, a

J. Brioni, A. Swensen, Lance Lee, 2015 .

Structure-activity studies and analgesic efficacy of N-(3-pyridinyl)-bridged bicyclic diamines, exceptionally potent agonists at nicotinic acetylcholine receptors.

Arianna Gelain, Daniela Barlocco, Lucio Toma, 2007, Journal of medicinal chemistry.

General Asymmetric Synthesis of Densely Functionalized Pyrrolidines via Endo-Selective [3+2] Cycloaddition of β-Quaternary-Substituted Nitroalkenes and Azomethine Ylides.

E. Voight, Stephen N. Greszler, Gang Zhao, 2020, The Journal of organic chemistry.

Biological Characterization of F508delCFTR Protein Processing by the CFTR Corrector ABBV-2222/GLPG2222

C. Tse, D. Cyr, A. Swensen, 2019, The Journal of Pharmacology and Experimental Therapeutics.

Mechanistic insights into the analgesic efficacy of A-1264087, a novel neuronal Ca(2+) channel blocker that reduces nociception in rat preclinical pain models.

A. Swensen, Chih-Hung Lee, T. Neelands, 2014, The journal of pain : official journal of the American Pain Society.

A mixed Ca2+ channel blocker, A-1264087, utilizes peripheral and spinal mechanisms to inhibit spinal nociceptive transmission in a rat model of neuropathic pain.

A. Swensen, Lance Lee, M. Jarvis, 2014, Journal of neurophysiology.

A mixed Ca 2 channel blocker , A-1264087 , utilizes peripheral and spinal mechanisms to inhibit spinal nociceptive transmission in a rat model of neuropathic pain

A. Swensen, Lance Lee, M. Jarvis, 2013 .

From Bacterial Genomes to Novel Antibacterial Agents: Discovery, Characterization, and Antibacterial Activity of Compounds that Bind to HI0065 (YjeE) from Haemophilus influenzae

P. Hajduk, K. Comess, Liping Yu, 2007, Chemical biology & drug design.

Discovery of 4-[(2R,4R)-4-({[1-(2,2-Difluoro-1,3-benzodioxol-5-yl)cyclopropyl]carbonyl}amino)-7-(difluoromethoxy)-3,4-dihydro-2H-chromen-2-yl]benzoic Acid (ABBV/GLPG-2222), a Potent Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Corrector for the Treatment of Cystic Fibrosis.

A. Bogdan, C. Tse, A. Swensen, 2018, Journal of medicinal chemistry.

Discovery of ABBV/GLPG-3221, a Potent Corrector of CFTR for the Treatment of Cystic Fibrosis.

A. Bogdan, C. Tse, A. Swensen, 2019, ACS medicinal chemistry letters.

Mechanistic insights into the analgesic efficacy of A-1264087, a novel neuronal Ca(2+) channel blocker that reduces nociception in rat preclinical pain models.

A. Swensen, Chih-Hung Lee, T. Neelands, 2014, The journal of pain : official journal of the American Pain Society.

Synthesis and structure-activity studies on N-[5-(1H-imidazol-4-yl)-5,6,7,8-tetrahydro-1-naphthalenyl]methanesulfonamide, an imidazole-containing alpha(1A)-adrenoceptor agonist.

J. Sullivan, M. Nakane, J. Kuk, 2004, Journal of medicinal chemistry.