G. Lee

Genome editing-mediated knock-in of therapeutic genes ameliorates the disease phenotype in a model of hemophilia

Seokjoong Kim, D. Song, Hye-Kyung Oh, 2022, Molecular therapy. Nucleic acids.

Positive Correlation between nNOS and Stress-Activated Bowel Motility Is Confirmed by In Vivo HiBiT System

O. Koo, S. Yeom, J. Han, 2021, Cells.

Morc2a p.S87L mutant mice develop peripheral and central neuropathies associated with neuronal DNA damage and apoptosis

G. Kwak, Byung-Ok Choi, S. Yeom, 2021, Disease models & mechanisms.

In vivo delivery of CRISPR-Cas9 using lipid nanoparticles enables antithrombin gene editing for sustainable hemophilia A and B therapy

Seokjoong Kim, Jun Chang, Hyukjin Lee, 2022, Science advances.

In vivo multiplex gene targeting with Streptococcus pyogens and Campylobacter jejuni Cas9 for pancreatic cancer modeling in wild-type animal

O. Koo, Y. Choi, S. Yeom, 2020, Journal of veterinary science.

In vivo genome editing for hemophilia B therapy by the combination of rebalancing and therapeutic gene knockin using a viral and non-viral vector.

Seokjoong Kim, Hyukjin Lee, D. Song, 2023, Molecular therapy. Nucleic acids.

Novel Severe Hemophilia A Mouse Model with Factor VIII Intron 22 Inversion

D. Song, S. Yeom, J. Han, 2021, Biology.

In vivo genome editing using 244-cis LNPs and low-dose AAV achieves therapeutic threshold in hemophilia A mice

S. Yeom, J. Han, Jeong Hyeon Lee, 2023, Molecular therapy. Nucleic acids.