L. Van Mellaert

发表

Evaluation of a novel subtilisin inhibitor gene and mutant derivatives for the expression and secretion of mouse tumor necrosis factor alpha by Streptomyces lividans

E. Sablon, C. Dillen, J. Anné, 1997, Applied and environmental microbiology.

sesC as a genetic marker for easy identification of Staphylococcus epidermidis from other isolates.

M. Van Ranst, J. van Eldere, M. Shahrooei, 2016, Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases.

Influence of charge variation in the Streptomyces venezuelae a-amylase signal peptide on heterologous protein production by Streptomyces lividans

J. Anné, E. Lammertyn, S. Schacht, 1998, Applied Microbiology and Biotechnology.

Further biological and molecular characterization of actinophage VWB.

P. Herdewijn, L. Mellaert, A. Aerschot, 1990, Journal of general microbiology.

Determination of the packaging capacity of bacteriophage VWB

J. Anné, H. Eyssen, L. Van Mellaert, 1990, Journal of bacteriology.

The Possible Role of Staphylococcus epidermidis LPxTG Surface Protein SesC in Biofilm Formation

P. Baatsen, J. O’Gara, B. Stijlemans, 2016, PloS one.

Transcriptomic and fluxomic changes in Streptomyces lividans producing heterologous protein

B. Nicolai, J. Kalinowski, C. Rückert, 2018, Microbial Cell Factories.

Large-scale production of a thermostable Rhodothermus marinus cellulase by heterologous secretion from Streptomyces lividans

S. Karamanou, K. Bernaerts, J. Anné, 2017, Microbial Cell Factories.

Streptomyces as host for recombinant production of Mycobacterium tuberculosis proteins.

C. Vallín, J. Anné, I. Hernández, 2006, Tuberculosis.

Recombinant production of Streptococcus equisimilis streptokinase by Streptomyces lividans

C. Vallín, J. Anné, E. Pimienta, 2007, Microbial cell factories.

Characterization of the Streptomyces lividans PspA Response

J. Anné, K. Vrancken, L. Van Mellaert, 2008, Journal of bacteriology.

pspA overexpression in Streptomyces lividans improves both Sec- and Tat-dependent protein secretion

J. Anné, E. Lammertyn, K. Vrancken, 2007, Applied Microbiology and Biotechnology.

Functional analysis of TatA and TatB in Streptomyces lividans.

J. Anné, E. Lammertyn, K. Vrancken, 2005, Biochemical and biophysical research communications.

Family-wide analysis of aminoacyl-sulfamoyl-3-deazaadenosine analogues as inhibitors of aminoacyl-tRNA synthetases.

M. Froeyen, A. Van Aerschot, S. Strelkov, 2018, European journal of medicinal chemistry.

The potential therapeutic gain of radiation-associated gene therapy with the suicide gene cytosine deaminase.

P. Lambin, W. Landuyt, J. Theys, 2000, International journal of radiation biology.

Site-specific integration of bacteriophage VWB genome into Streptomyces venezuelae and construction of a VWB-based integrative vector.

L. Mellaert, J. Anné, L. van Mellaert, 1998, Microbiology.

Staphylococcal biofilm growth on smooth and porous titanium coatings for biomedical applications.

J. Schrooten, L. Geris, J. Vleugels, 2014, Journal of biomedical materials research. Part A.

Twin-Arginine Translocation Pathway inStreptomyces lividans

J. Anné, E. Lammertyn, N. Geukens, 2001, Journal of bacteriology.

Surface plasmon resonance-based interaction studies reveal competition of Streptomyces lividans type I signal peptidases for binding preproteins.

Kristof Vrancken, Filip Frederix, Kristien Bonroy, 2006, Microbiology.

The type II signal peptidase of Legionella pneumophila.

J. Anné, E. Lammertyn, E. De Buck, 2006, Research in microbiology.

Evaluation of the type I signal peptidase as antibacterial target for biofilm-associated infections of Staphylococcus epidermidis.

P. Herdewijn, A. Van Aerschot, J. Anné, 2009, Microbiology.

Molecular and functional characterization of type I signal peptidase from Legionella pneumophila.

J. Anné, E. Lammertyn, E. De Buck, 2004, Microbiology.

Membrane Topology of the Streptomyces lividans Type I Signal Peptidases

S. Bron, R. Mellado, Y. Engelborghs, 2001, Journal of bacteriology.

Preclinical studies on thiocarboxanilide UC‐781 as a virucidal agent

L. van Damme, E. De Clercq, L. Naesens, 1998, AIDS.

Protein secretion biotechnology in Gram-positive bacteria with special emphasis on Streptomyces lividans.

J. V. Van Impe, K. Bernaerts, J. Anné, 2014, Biochimica et biophysica acta.

Streptomyces lividans as host for heterologous protein production.

J. Anné, L. van Mellaert, L. Van Mellaert, 1993, FEMS microbiology letters.

Recombinant protein production and streptomycetes.

J. V. Van Impe, K. Bernaerts, J. Anné, 2012, Journal of biotechnology.

Spores of Clostridium engineered for clinical efficacy and safety cause regression and cure of tumors in vivo

L. Dubois, J. Heap, J. Theys, 2014, Oncotarget.

Clostridium spores as anti-tumour agents.

J. Anné, S. Barbé, L. Van Mellaert, 2006, Trends in microbiology.

Secretory production of biologically active rat interleukin-2 by Clostridium acetobutylicum DSM792 as a tool for anti-tumor treatment.

Jan Theys, Philippe Lambin, Nick Geukens, 2005, FEMS microbiology letters.

Tumor-specific gene delivery using genetically engineered bacteria.

P. Lambin, S. Barbe, W. Landuyt, 2003, Current gene therapy.

The Use of Radiation-Induced Bacterial Promoters in Anaerobic Conditions: A Means to Control Gene Expression in Clostridium-Mediated Therapy for Cancer

P. Lambin, W. Landuyt, J. Theys, 2001, Radiation research.

Increasing specificity of anti-tumor therapy: cytotoxic protein delivery by non-pathogenic clostridia under regulation of radio-induced promoters.

P. Lambin, W. Landuyt, J. Theys, 2001, Anticancer research.

Improvement of Clostridium tumour targeting vectors evaluated in rat rhabdomyosarcomas.

P. Lambin, E. Bosmans, A. Rijnders, 2001, FEMS immunology and medical microbiology.

Stable Escherichia coli-Clostridium acetobutylicum Shuttle Vector for Secretion of Murine Tumor Necrosis Factor Alpha

P. Lambin, P. Lambin, P. Dürre, 1999, Applied and Environmental Microbiology.

Colonisation of Clostridium in the body is restricted to hypoxic and necrotic areas of tumours.

P. Lambin, L. Mellaert, W. Landuyt, 1998, Anaerobe.

Complete genomic nucleotide sequence and analysis of the temperate bacteriophage VWB.

L. Mellaert, H. Liesegang, C. Raasch, 2005, Virology.

Enhanced protein secretion in reduced genome strains of Streptomyces lividans

K. Bernaerts, S. Carpentier, J. Kormanec, 2023, bioRxiv.

Functional large-scale production of a novel Jonesia sp. xyloglucanase by heterologous secretion from Streptomyces lividans.

S. Karamanou, J. Anné, A. Economou, 2006, Journal of biotechnology.

Immunoprophylaxis and immunotherapy of Staphylococcus epidermidis infections: challenges and prospects

J. Eldere, M. Shahrooei, L. Van Mellaert, 2012, Expert review of vaccines.

Chlorite-Oxidized Oxyamylose (COAM) Has Antibacterial Activity and Positively Affects Skin Wound Healing

K. Nylander, G. Opdenakker, T. Alamäe, 2022, Journal of inflammation research.

Improved PCR-based method for the direct screening of Streptomyces transformants.

J. Anné, N. Geukens, L. Van Mellaert, 2003, Journal of microbiological methods.

Inefficacy of vancomycin and teicoplanin in eradicating and killing Staphylococcus epidermidis biofilms in vitro.

P. Baatsen, M. Roriz, J. van Eldere, 2015, International journal of antimicrobial agents.

Reduction of Biofilm Infection Risks and Promotion of Osteointegration for Optimized Surfaces of Titanium Implants

J. Vleugels, J. Anné, D. Pierron, 2012, Advanced healthcare materials.

Perturbation of Alphavirus and Flavivirus Infectivity by Components of the Bacterial Cell Wall

P. Baatsen, L. Delang, R. Abdelnabi, 2021, bioRxiv.

Alphavirus and flavivirus infectivity is disrupted by components of the bacterial cell wall

P. Baatsen, L. Delang, R. Abdelnabi, 2021 .

Inactivation of the 20S proteasome in Streptomyces lividans and its influence on the production of heterologous proteins.

J. Anné, Yuan Li, B. Hong, 2005, Microbiology.

Molecular characterization of a novel subtilisin inhibitor protein produced by Streptomyces venezuelae CBS762.70.

P. Proost, E. Sablon, J. Van Damme, 1998, DNA sequence : the journal of DNA sequencing and mapping.

Clostridium spores for tumor-specific drug delivery.

P. Lambin, W. Landuyt, J. Theys, 2002, Anti-cancer drugs.

The importance of the Tat-dependent protein secretion pathway in Streptomyces as revealed by phenotypic changes in tat deletion mutants and genome analysis.

J. Anné, E. Lammertyn, N. Geukens, 2004, Microbiology.

Bacterial colonisation of porous titanium coatings for orthopaedic implant applications – effect of surface roughness and porosity

J. Schrooten, J. Vleugels, J. Anné, 2013 .

Controlled release of chlorhexidine antiseptic from microporous amorphous silica applied in open porosity of an implant surface.

J. Vleugels, J. Martens, J. Duyck, 2011, International journal of pharmaceutics.

A putative twin-arginine translocation pathway in Legionella pneumophila.

J. Anné, E. Lammertyn, E. De Buck, 2004, Biochemical and Biophysical Research Communications - BBRC.

Efficient isolation of total RNA from Clostridium without DNA contamination.

P. Lambin, J. Anné, S. Nuyts, 2001, Journal of microbiological methods.

Comparison of the Sec and Tat secretion pathways for heterologous protein production by Streptomyces lividans.

J. Anné, L. van Mellaert, E. Lammertyn, 2004, Journal of biotechnology.

Insertion or Deletion of the Cheo Box Modifies Radiation Inducibility of Clostridium Promoters

P. Lambin, E. Bosmans, W. Landuyt, 2001, Applied and Environmental Microbiology.

Real-time quantitative RT-PCR and detection of tumour cell dissemination in breast cancer patients: plasmid versus cell line dilutions.

R. Paridaens, M. Christiaens, A. V. van Oosterom, 2003, Annals of oncology : official journal of the European Society for Medical Oncology.

The use of clostridial spores for cancer treatment

J. Anné, S. Barbé, L. Van Mellaert, 2006, Journal of applied microbiology.

Clostridium as a tumor-specific delivery system of therapeutic proteins.

P. Lambin, J. Theys, J. Anné, 2001, Cancer detection and prevention.

Legionella pneumophila Philadelphia-1 tatB and tatC affect intracellular replication and biofilm formation.

J. Anné, E. Lammertyn, E. De Buck, 2005, Biochemical and biophysical research communications.

The Tat pathway in Streptomyces lividans: interaction of Tat subunits and their role in translocation.

J. Anné, K. Vrancken, N. Geukens, 2007, Microbiology.

Efficient secretion of biologically active mouse tumor necrosis factor alpha by Streptomyces lividans.

L. Mellaert, P. Proost, H. Heremans, 1994, Gene.

Monitoring Protein Secretion in Streptomyces Using Fluorescent Proteins

M. Oldiges, S. Karamanou, J. Anné, 2018, Front. Microbiol..

The use of the cMyc epitope tag can be problematic for protein detection in Legionella pneumophila.

J. Anné, E. Lammertyn, E. De Buck, 2004, Journal of microbiological methods.

Scalable Synthesis, In Vitro cccDNA Reduction, and In Vivo Antihepatitis B Virus Activity of a Phosphonomethoxydeoxythreosyl Adenine Prodrug.

R. Ptak, P. Herdewijn, M. Luo, 2020, Journal of medicinal chemistry.

Ses proteins as possible targets for vaccine development against Staphylococcus epidermidis infections.

E. Vanstreels, J. van Eldere, M. Shahrooei, 2018, The Journal of infection.

First proteomic analysis of Legionella pneumophila based on its developing genome sequence.

L. Arckens, S. Clerens, J. Anné, 2005, Research in microbiology.

Metabolic impact assessment for heterologous protein production in Streptomyces lividans based on genome-scale metabolic network modeling.

J. V. Van Impe, K. Bernaerts, J. Anné, 2013, Mathematical biosciences.

Physical requirements for in vitro processing of the Streptomyces lividans signal peptidases.

R. Mellado, Y. Engelborghs, J. Anné, 2002, Journal of biotechnology.