L. Ranshaw

发表

In Vivo Characterization of GSK256066, a High-Affinity Inhaled Phosphodiesterase 4 Inhibitor

Richard Graham Knowles, C. Tralau-Stewart, A. Nials, 2011, Journal of Pharmacology and Experimental Therapeutics.

GSK256066, an Exceptionally High-Affinity and Selective Inhibitor of Phosphodiesterase 4 Suitable for Administration by Inhalation: In Vitro, Kinetic, and In Vivo Characterization

Richard Graham Knowles, R. Williamson, C. Tralau-Stewart, 2011, Journal of Pharmacology and Experimental Therapeutics.

Addressing species specific metabolism and solubility issues in a quinoline series of oral PDE4 inhibitors.

B. Judkins, T. Shipley, A. Craven, 2010, Bioorganic & medicinal chemistry letters.

Quinolines as a novel structural class of potent and selective PDE4 inhibitors: optimisation for oral administration.

M. Lindvall, D. Somers, T. Shipley, 2009, Bioorganic & medicinal chemistry letters.

GSK 256066 , An Exceptionally High Affinity and Selective Inhibitor of PDE 4 Suitable for Administration by Inhalation : In vitro , Kinetic and In vivo Characterisation

Richard Graham Knowles, R. Williamson, C. Tralau-Stewart, 2011 .

Pyrazolopyridines as a novel structural class of potent and selective PDE4 inhibitors.

M. Lindvall, P. Jones, D. Somers, 2008, Bioorganic & medicinal chemistry letters.

N-4-Pyrimidinyl-1H-indazol-4-amine inhibitors of Lck: indazoles as phenol isosteres with improved pharmacokinetics.

P. Bamborough, R. Angell, L. Fazal, 2007, Bioorganic & medicinal chemistry letters.

The aliphatic oxidation of salmeterol to alpha-hydroxysalmeterol in human liver microsomes is catalyzed by CYP3A.

M. Tarbit, M. Bayliss, P. Eddershaw, 1996, Drug metabolism and disposition: the biological fate of chemicals.

The use of hydrazine-based derivatization reagents for improved sensitivity and detection of carbonyl containing compounds using MALDI-MSI

M. Clench, B. Flinders, L. Ranshaw, 2015, Analytical and Bioanalytical Chemistry.

Monitoring the three‐dimensional distribution of endogenous species in the lungs by matrix‐assisted laser desorption/ionization mass spectrometry imaging

R. Heeren, M. Clench, B. Flinders, 2021, Rapid Communications in Mass Spectrometry.

Quinolines as a novel structural class of potent and selective PDE4 inhibitors. Optimisation for inhaled administration.

Tony W Dean, Michael D. Woodrow, D. Somers, 2009, Bioorganic & medicinal chemistry letters.

Monitoring the three-dimensional distribution of endogenous species in the lungs by MALDI-MSI.

R. Heeren, M. Clench, B. Flinders, 2020, Rapid communications in mass spectrometry : RCM.