Stefan Michiels

发表

A Dual Model for Prioritizing Cancer Mutations in the Non-coding Genome Based on Germline and Somatic Events

Daniel Gautheret, Jia Li, Marie-Anne Poursat, 2015, PLoS Comput. Biol..

Robust estimation of the expected survival probabilities from high-dimensional Cox models with biomarker-by-treatment interactions in randomized clinical trials

Federico Rotolo, Stefan Michiels, Nils Ternès, 2017, BMC Medical Research Methodology.

Défis statistiques posés par les biopuces : autant d’espoir que de faux positifs ?

Stefan Michiels, Serge Koscielny, T. Boulet, 2007 .

False discovery rate, sensitivity and sample size for microarray studies

Yudi Pawitan, Stefan Michiels, Serge Koscielny, 2005, Bioinform..

Group sequential adaptive designs in series of time-to-event randomised trials in rare diseases: A simulation study

Marie-Cécile Le Deley, Gwénaël Le Teuff, Stefan Michiels, 2020, Statistical methods in medical research.

Accounting for grouped predictor variables or pathways in high-dimensional penalized Cox regression models

Stefan Michiels, Riccardo De Bin, Shaima Belhechmi, 2020, BMC Bioinformatics.

biospear: an R package for biomarker selection in penalized Cox regression

Federico Rotolo, Stefan Michiels, Nils Ternès, 2018, Bioinform..

A Poisson approach to the validation of failure time surrogate endpoints in individual patient data meta-analyses

Tomasz Burzykowski, Federico Rotolo, Marc Buyse, 2019, Statistical methods in medical research.

Bias in the estimation of false discovery rate in microarray studies

Karuturi R. Krishna Murthy, Yudi Pawitan, Stefan Michiels, 2005, Bioinform..

surrosurv: An R package for the evaluation of failure time surrogate endpoints in individual patient data meta-analyses of randomized clinical trials

Federico Rotolo, Xavier Paoletti, Stefan Michiels, 2018, Comput. Methods Programs Biomed..

Dataset for: Multivariate joint frailty model for the analysis of nonlinear tumor kinetics and dynamic predictions of death

Wiley Admin, Virginie Rondeau, Stefan Michiels, 2018 .

Evaluation of Treatment Effect with Paired Failure Times in a Single-Arm Phase II Trial in Oncology

Federico Rotolo, Olivier Boucher, Stefan Michiels, 2018, Comput. Math. Methods Medicine.

High-Dimensional, Penalized-Regression Models in Time-to-Event Clinical Trials

Federico Rotolo, Stefan Michiels, Nils Ternès, 2019 .

A benchmark study of scoring methods for non‐coding mutations

Daniel Gautheret, Damien Drubay, Stefan Michiels, 2018, Bioinform..

Multidimensionality of microarrays: Statistical challenges and (im)possible solutions

Stefan Michiels, Andrew Kramar, Serge Koscielny, 2011, Molecular oncology.

Tutorial in Joint Modeling and Prediction: a Statistical Software for Correlated Longitudinal Outcomes, Recurrent Events and a Terminal Event

Virginie Rondeau, Stefan Michiels, Alexandre Laurent, 2017, 1701.03675.

Penalized Poisson model for network meta-analysis of individual patient time-to-event data.

Gwénaël Le Teuff, Stefan Michiels, Edouard Ollier, 2021, Statistics in medicine.

Multivariate joint frailty model for the analysis of nonlinear tumor kinetics and dynamic predictions of death

Virginie Rondeau, Stefan Michiels, Christophe Tournigand, 2018, Statistics in medicine.

Prediction of cancer outcome with microarrays: a multiple random validation strategy

Stefan Michiels, Serge Koscielny, S. Michiels, 2005, The Lancet.

Tumor-Infiltrating Lymphocytes and Associations With Pathological Complete Response and Event-Free Survival in HER2-Positive Early-Stage Breast Cancer Treated With Lapatinib and Trastuzumab: A Secondary Analysis of the NeoALTTO Trial.

Carsten Denkert, Stefan Michiels, Christos Sotiriou, 2015, JAMA oncology.

Molecular Characterization of Breast Cancer with High-Resolution Oligonucleotide Comparative Genomic Hybridization Array

Philippe Dessen, Stefan Michiels, Lajos Pusztai, 2009, Clinical Cancer Research.

Surrogate End Points for Overall Survival in Loco-Regionally Advanced Nasopharyngeal Carcinoma

Federico Rotolo, Li Zhang, Stefan Michiels, 2017 .

Disease-free survival as a surrogate for overall survival in adjuvant trials of gastric cancer: a meta-analysis.

Satoshi Morita, Yasuo Ohashi, Junichi Sakamoto, 2013, Journal of the National Cancer Institute.

PIK3CA Genotype and a PIK3CA Mutation-Related Gene Signature and Response to Everolimus and Letrozole in Estrogen Receptor Positive Breast Cancer

John M. S. Bartlett, Stefan Michiels, Christos Sotiriou, 2013, PloS one.

A comparison between different prediction models for invasive breast cancer occurrence in the French E3N cohort

Stefan Michiels, Laura Baglietto, Guy Fagherazzi, 2015, Breast Cancer Research and Treatment.

Gene modules and response to neoadjuvant chemotherapy in breast cancer subtypes: a pooled analysis.

Stefan Michiels, Benjamin Haibe-Kains, Christine Desmedt, 2012, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Benefit of Adjuvant Chemotherapy for Resectable Gastric Cancer

Yasuo Ohashi, Junichi Sakamoto, Tomasz Burzykowski, 2009 .

Gene expression profiling: does it add predictive accuracy to clinical characteristics in cancer prognosis?

Stefan Michiels, Daniela Dunkler, Michael Schemper, 2007, European journal of cancer.

Tumor-Infiltrating Lymphocytes and Prognosis: A Pooled Individual Patient Analysis of Early-Stage Triple-Negative Breast Cancers.

Heikki Joensuu, Carsten Denkert, Damien Drubay, 2019, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

High-Throughput Genomics and Clinical Outcome in Hard-to-Treat Advanced Cancers: Results of the MOSCATO 01 Trial.

Marie-Cécile Le Deley, Stefan Michiels, Caroline Even, 2017, Cancer discovery.

Role of chemotherapy for advanced/recurrent gastric cancer: an individual-patient-data meta-analysis.

Satoshi Morita, Yasuo Ohashi, Junichi Sakamoto, 2013, European journal of cancer.

Genetic polymorphisms in 85 DNA repair genes and bladder cancer risk.

Philippe Dessen, Stefan Michiels, Agnès Laplanche, 2009, Carcinogenesis.

A joint model for the dependence between clustered times to tumour progression and deaths: A meta-analysis of chemotherapy in head and neck cancer

Virginie Rondeau, Stefan Michiels, J. Pignon, 2015, Statistical methods in medical research.

Standardized evaluation of tumor-infiltrating lymphocytes in breast cancer: results of the ring studies of the international immuno-oncology biomarker working group

Carsten Denkert, Jan Budczies, David L Rimm, 2016, Modern Pathology.

Joint model for left‐censored longitudinal data, recurrent events and terminal event: Predictive abilities of tumor burden for cancer evolution with application to the FFCD 2000–05 trial

Virginie Rondeau, Cécile Proust-Lima, Stefan Michiels, 2016, Biometrics.

Integrating biomarkers in clinical trials

Daniel J Sargent, Marc Buyse, Stefan Michiels, 2011, Expert review of molecular diagnostics.

Progression-free survival as a surrogate for overall survival in advanced/recurrent gastric cancer trials: a meta-analysis.

Satoshi Morita, Yasuo Ohashi, Junichi Sakamoto, 2013, Journal of the National Cancer Institute.

Steps forward for cancer precision medicine

Sabine Tejpar, Jeffrey A. Moscow, John W. M. Martens, 2018, Nature Reviews Drug Discovery.

Identification of biomarker‐by‐treatment interactions in randomized clinical trials with survival outcomes and high‐dimensional spaces

Federico Rotolo, Georg Heinze, Stefan Michiels, 2016, Biometrical journal. Biometrische Zeitschrift.

Meta-analysis when only the median survival times are known: A comparison with individual patient data results

Stefan Michiels, Pascal Piedbois, Sarah Burdett, 2005, International Journal of Technology Assessment in Health Care.

Empirical extensions of the lasso penalty to reduce the false discovery rate in high‐dimensional Cox regression models

Federico Rotolo, Stefan Michiels, Nils Ternès, 2016, Statistics in medicine.

Leukemia-free survival as a surrogate end point for overall survival in the evaluation of maintenance therapy for patients with acute myeloid leukemia in complete remission

Marc Buyse, Stefan Michiels, M. Buyse, 2011, Haematologica.

DNA methylation profiling reveals a predominant immune component in breast cancers

Benjamin Haibe-Kains, Stefan Michiels, Matthieu Defrance, 2011, EMBO molecular medicine.

Surrogate End Points for Overall Survival in Loco-Regionally Advanced Nasopharyngeal Carcinoma: An Individual Patient Data Meta-analysis

Federico Rotolo, Stefan Michiels, George Fountzilas, 2017, Journal of the National Cancer Institute.

Prognostic and predictive value of tumor-infiltrating lymphocytes in a phase III randomized adjuvant breast cancer trial in node-positive breast cancer comparing the addition of docetaxel to doxorubicin with doxorubicin-based chemotherapy: BIG 02-98.

Stefan Michiels, Christos Sotiriou, Martine J Piccart, 2013, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Multiple testing of treatment‐effect‐modifying biomarkers in a randomized clinical trial with a survival endpoint

Stefan Michiels, Richard F Potthoff, Stephen L George, 2011, Statistics in medicine.

Progression-free survival (PFS) as a surrogate for overall survival (OS) in patients with advanced colorectal cancer: An analysis of 3159 patients randomized in 11 trials

Tomasz Burzykowski, J. P. Pignon, Kevin Carroll, 2005 .

CD4⁺ follicular helper T cell infiltration predicts breast cancer survival.

Benjamin Haibe-Kains, Stefan Michiels, Christine Desmedt, 2013, The Journal of clinical investigation.

Individual- and trial-level surrogacy in colorectal cancer

Tomasz Burzykowski, Kevin Carroll, Marc Buyse, 2008, Statistical methods in medical research.

Neoadjuvant buparlisib plus trastuzumab and paclitaxel for women with HER2+ primary breast cancer: A randomised, double-blind, placebo-controlled phase II trial (NeoPHOEBE).

Carsten Denkert, Stefan Michiels, Mahdi Rezai, 2017, European journal of cancer.

Surrogate endpoints for overall survival in chemotherapy and radiotherapy trials in operable and locally advanced lung cancer: a re-analysis of meta-analyses of individual patients' data

Caroline Domerg, Stefan Michiels, Herbert Pang, 2013, The Lancet. Oncology.

Assessing Tumor-Infiltrating Lymphocytes in Solid Tumors: A Practical Review for Pathologists and Proposal for a Standardized Method from the International Immuno-Oncology Biomarkers Working Group: Part 2: TILs in Melanoma, Gastrointestinal Tract Carcinomas, Non-Small Cell Lung Carcinoma and Mesothe

Carsten Denkert, Fred Hirsch, Benjamin Solomon, 2017, Advances in anatomic pathology.

Surrogate endpoints for overall survival in locally advanced head and neck cancer: meta-analyses of individual patient data.

Tomasz Burzykowski, Marc Buyse, Stefan Michiels, 2009, The Lancet. Oncology.

CD 4 + follicular helper T cell infiltration predicts breast cancer survival

Benjamin Haibe-Kains, Stefan Michiels, Christine Desmedt, 2013 .

Multifactorial approach to predicting resistance to anthracyclines.

Yuan Qi, Gianluca Bontempi, Marc Buyse, 2011, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Application of an acceptance sampling plan for post-production quality control of chemotherapeutic batches in an hospital pharmacy.

Isabelle Borget, Stefan Michiels, Philippe Bourget, 2006, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.