Tomas Mustelin

发表

Figure 3, Profiling of the 21 most active VHR screening hits at 20 µM against VHR (AID-2074) & HePTP (AID-2082)

Stefan Vasile, Ying Su, Thomas D.Y. Chung, 2010 .

Negative Feedback Regulation of the Tumor

Nunzio Bottini, Tomas Mustelin, Eileen D. Adamson, 2013 .

Table 4, Submission of Probe and 5 analogs to the MLSMR

Stefan Vasile, Thomas D.Y. Chung, Eduard Sergienko, 2010 .

Selective HePTP Inhibitors: Probe 1

Thomas D.Y. Chung, Eduard Sergienko, Russell Dahl, 2010 .

SUMO1 modification of PTEN regulates tumorigenesis by controlling its association with the plasma membrane

Jian Zhang, Tomas Mustelin, Ting Shi, 2012, Nature Communications.

Crosstalk between cAMP-dependent kinase and MAP kinase through a protein tyrosine phosphatase

Tomas Mustelin, Scott Williams, T. Mustelin, 1999, Nature Cell Biology.

Autoimmune-associated lymphoid tyrosine phosphatase is a gain-of-function variant

Nunzio Bottini, Francesco Cucca, Lutz Tautz, 2005, Nature Genetics.

Activation of C-terminal Src kinase (Csk) by phosphorylation at serine-364 depends on the Csk-Src homology 3 domain.

Sheraz Yaqub, Tomas Mustelin, Knut Martin Torgersen, 2003, The Biochemical journal.

NMR-based techniques in the hit identification and optimisation processes

Dawoon Jung, Maurizio Pellecchia, Lutz Tautz, 2004, Expert opinion on therapeutic targets.

Multidentate small-molecule inhibitors of vaccinia H1-related (VHR) phosphatase decrease proliferation of cervix cancer cells.

Stefan Vasile, Maurizio Pellecchia, Fabio Cerignoli, 2009, Journal of medicinal chemistry.

A functional variant of lymphoid tyrosine phosphatase is associated with type I diabetes

Nunzio Bottini, Maurizio Pellecchia, Tomas Mustelin, 2004, Nature Genetics.

Cooperative Phosphorylation of the Tumor Suppressor Phosphatase and Tensin Homologue (PTEN) by Casein Kinases and Glycogen Synthase Kinase 3β*

Tomas Mustelin, Scott Williams, T. Mustelin, 2005, Journal of Biological Chemistry.

Activation of the Cooh-Terminal Src Kinase (Csk) by Camp-Dependent Protein Kinase Inhibits Signaling through the T Cell Receptor

Tomas Mustelin, Knut Martin Torgersen, T. Mustelin, 2001, The Journal of experimental medicine.

In Silico Screening for PTPN22 Inhibitors: Active Hits from an Inactive Phosphatase Conformation

Lutz Tautz, Tomas Mustelin, Shuangding Wu, 2009, ChemMedChem.

Loss of the VHR dual-specific phosphatase causescell-cycle arrest and senescence

Fabio Cerignoli, Tomas Mustelin, Souad Rahmouni, 2006, Nature Cell Biology.

Development of molecular probes for second-site screening and design of protein tyrosine phosphatase inhibitors.

Kristiina Vuori, Maurizio Pellecchia, Lutz Tautz, 2007, Journal of medicinal chemistry.

Haematopoietic protein tyrosine phosphatase (HePTP) phosphorylation by cAMP-dependent protein kinase in T-cells: dynamics and subcellular location.

Nunzio Bottini, Tomas Mustelin, Scott Williams, 2004, The Biochemical journal.

Carbon materials: Nanosynthesis by candlelight.

Tomas Mustelin, Massimo Bottini, T. Mustelin, 2007, Nature nanotechnology.

Synthesis and characterization of supramolecular nanostructures of carbon nanotubes and ruthenium-complex Luminophores.

Stefano Bellucci, Tomas Mustelin, Andrea Magrini, 2006, Journal of nanoscience and nanotechnology.

Release from Tonic Inhibition of T Cell Activation through Transient Displacement of C-terminal Src Kinase (Csk) from Lipid Rafts*

Sheraz Yaqub, Tomas Mustelin, Burkhart Schraven, 2001, The Journal of Biological Chemistry.

Characterization of TCR‐induced receptor‐proximal signaling events negatively regulated by the protein tyrosine phosphatase PEP

Tomas Mustelin, Scott Williams, T. Mustelin, 1999, European journal of immunology.

Luminescent silica nanobeads: characterization and evaluation as efficient cytoplasmatic transporters for T-lymphocytes.

Maurizio Pellecchia, Marilisa Leone, Fabio Cerignoli, 2007, Journal of the American Chemical Society.

Inhibition of lymphoid tyrosine phosphatase by benzofuran salicylic acids.

Caty Chung, Stephan C Schürer, Yuli Xie, 2011, Journal of medicinal chemistry.

Positive and negative regulation of T-cell activation through kinases and phosphatases.

Tomas Mustelin, T. Mustelin, K. Taskén, 2003, The Biochemical journal.

Quantum dot-doped silica nanoparticles as probes for targeting of T-lymphocytes

Fabio Cerignoli, Tomas Mustelin, Andrea Magrini, 2007, International journal of nanomedicine.

Covalent decoration of multi-walled carbon nanotubes with silica nanoparticles.

Nunzio Bottini, Stefano Bellucci, Lutz Tautz, 2005, Chemical communications.

Differential and multiple binding of signal transducing molecules to the ITAMs of the TCR‐ζ chain

Tomas Mustelin, T. Vorherr, T. Mustelin, 1996, Journal of cellular biochemistry.

Protein tyrosine phosphatases and the immune response

Nunzio Bottini, Tomas Mustelin, N. Bottini, 2005, Nature Reviews Immunology.