A. Lulla

发表

Bindarit, an Inhibitor of Monocyte Chemotactic Protein Synthesis, Protects against Bone Loss Induced by Chikungunya Virus Infection

N. Sims, N. Walsh, A. Merits, 2014, Journal of Virology.

Insertion of EGFP into the replicase gene of Semliki Forest virus results in a novel , genetically stable marker virus

J. Fazakerley, R. Fragkoudis, A. Merits, 2007 .

Semliki Forest Virus-Induced Endoplasmic Reticulum Stress Accelerates Apoptotic Death of Mammalian Cells

A. Kohl, J. Fazakerley, R. Fragkoudis, 2010, Journal of Virology.

Presentation Overrides Specificity: Probing the Plasticity of Alphaviral Proteolytic Activity through Mutational Analysis

A. Merits, V. Lulla, Kai Rausalu, 2013, Journal of Virology.

Age-Associated B cells predict impaired humoral immunity after COVID-19 vaccination in patients receiving immune checkpoint blockade

F. Hollfelder, M. MacFarlane, Md. Zulfekar Ali, 2022, medRxiv.

Novel Attenuated Chikungunya Vaccine Candidates Elicit Protective Immunity in C57BL/6 mice

P. Roques, P. Liljeström, J. Fazakerley, 2013, Journal of Virology.

Macromolecular Assembly-Driven Processing of the 2/3 Cleavage Site in the Alphavirus Replicase Polyprotein

A. Merits, V. Lulla, A. Lulla, 2011, Journal of Virology.

A Pathogenic Role for CD4+ T Cells during Chikungunya Virus Infection in Mice

L. Rénia, L. Ng, A. Merits, 2013, The Journal of Immunology.

Molecular Determinants of Substrate Specificity for Semliki Forest Virus Nonstructural Protease

T. Ahola, A. Merits, Kairit Tints, 2006, Journal of Virology.

Attenuation hotspots in neurotropic human astroviruses

S. Guix, V. Lulla, S. C. Graham, 2022, bioRxiv.

Microfluidics-enabled fluorescence-activated cell sorting of single pathogen-specific antibody secreting cells for the rapid discovery of monoclonal antibodies

C. Deane, F. Hollfelder, M. Raybould, 2023, bioRxiv.

Sequestration of G3BP coupled with efficient translation inhibits stress granules in Semliki Forest virus infection

G. B. Karlsson Hedestam, M. Panas, G. Mcinerney, 2012, Molecular biology of the cell.

Detection of Persistent Chikungunya Virus RNA but not Infectious Virus in Experimental Vertical Transmission in Aedes aegypti from Malaysia.

I. Sam, Y. Chan, I. Vythilingam, 2016, The American journal of tropical medicine and hygiene.

Inhibitors of Alphavirus Entry and Replication Identified with a Stable Chikungunya Replicon Cell Line and Virus-Based Assays

T. Ahola, M. Varjak, A. Merits, 2011, PloS one.

Alphaviral nonstructural protease and its polyprotein substrate: arrangements for the perfect marriage

Aleksei Lulla, A. Lulla, 2012 .

Safe and Effective Treatment of Experimental Neuroblastoma and Glioblastoma Using Systemically Delivered Triple MicroRNA-Detargeted Oncolytic Semliki Forest Virus

S. Nelander, M. Essand, A. Merits, 2016, Clinical Cancer Research.

Wolbachia Blocks Viral Genome Replication Early in Infection without a Transcriptional Response by the Endosymbiont or Host Small RNA Pathways

E. Miska, Punita Juneja, F. Jiggins, 2016, PLoS pathogens.

Characterization of Aedes aegypti Innate-Immune Pathways that Limit Chikungunya Virus Replication

A. Kohl, M. McFarlane, A. Failloux, 2014, PLoS neglected tropical diseases.

RIG-I and MDA-5 Detection of Viral RNA-dependent RNA Polymerase Activity Restricts Positive-Strand RNA Virus Replication

U. Toots, M. Ustav, A. Merits, 2013, PLoS pathogens.

Timeliness of Proteolytic Events Is Prerequisite for Efficient Functioning of the Alphaviral Replicase

A. Merits, V. Lulla, Sirle Saul, 2018, Journal of Virology.

Semliki Forest Virus Chimeras with Functional Replicase Modules from Related Alphaviruses Survive by Adaptive Mutations in Functionally Important Hot Spots

A. Merits, V. Lulla, Kai Rausalu, 2021, Journal of virology.

Mutation of CD2AP and SH3KBP1 Binding Motif in Alphavirus nsP3 Hypervariable Domain Results in Attenuated Virus

B. Thaa, G. Mcinerney, Sergo Kasvandik, 2018, Viruses.

Virus replicon particle based Chikungunya virus neutralization assay using Gaussia luciferase as readout

J. Drexler, C. Drosten, P. Liljeström, 2013, Virology Journal.

Functional Cross-talk between Distant Domains of Chikungunya Virus Non-structural Protein 2 Is Decisive for Its RNA-modulating Activity*

P. Das, A. Merits, A. Lulla, 2014, The Journal of Biological Chemistry.

Merits and RNA-modulating Activity Non-structural Protein 2 Is Decisive for Its Domains of Chikungunya Virus Functional Cross-talk between Distant Enzymology :

P. Das, A. Merits, A. Lulla, 2014 .

Molecular Defects Caused by Temperature-Sensitive Mutations in Semliki Forest Virus nsP1

T. Ahola, S. Sawicki, D. Sawicki, 2008, Journal of Virology.

Assembly of Replication-Incompetent African Horse Sickness Virus Particles: Rational Design of Vaccines for All Serotypes

M. Beer, P. Roy, K. Wernike, 2016, Journal of Virology.

Mutations Conferring a Noncytotoxic Phenotype on Chikungunya Virus Replicons Compromise Enzymatic Properties of Nonstructural Protein 2

P. Das, A. Merits, V. Lulla, 2014, Journal of Virology.

Loss of TLR3 aggravates CHIKV replication and pathology due to an altered virus-specific neutralizing antibody response

A. Andiappan, L. Rénia, L. Ng, 2014, EMBO molecular medicine.

Prime-Boost Immunization Strategies against Chikungunya Virus

L. Ng, P. Roques, P. Liljeström, 2014, Journal of Virology.

Viperin restricts chikungunya virus replication and pathology.

Angela Chow, Esther G. L. Koh, L. Ng, 2012, The Journal of clinical investigation.

Magnetic Fractionation and Proteomic Dissection of Cellular Organelles Occupied by the Late Replication Complexes of Semliki Forest Virus

L. Arike, L. Peil, A. Merits, 2013, Journal of Virology.

Anthraquinone derivatives as ADP-competitive inhibitors of liver pyruvate kinase.

J. Borén, M. Uhlén, A. Mardinoğlu, 2022, European journal of medicinal chemistry.

Multivalent bicyclic peptides are an effective antiviral modality that can potently inhibit SARS-CoV-2

Lee M. Tatham, J. Briggs, L. James, 2023, Nature communications.

Structure-Guided Chemical Optimization of Bicyclic Peptide (Bicycle) Inhibitors of Angiotensin-Converting Enzyme 2.

G. A. Bezerra, M. Hyvönen, P. Beswick, 2023, Journal of medicinal chemistry.

Tuning liver pyruvate kinase activity up or down with a new class of allosteric modulators.

J. Borén, M. Hyvönen, M. Grøtli, 2023, European journal of medicinal chemistry.

Novel Attenuated Chikungunya Vaccine Candidates Elicit Protective Immunity in C57BL/6 mice

P. Roques, P. Liljeström, J. Fazakerley, 2013, Journal of Virology.

Serendipitous Identification of a Covalent Activator of Liver Pyruvate Kinase

J. Borén, M. Uhlén, A. Mardinoğlu, 2022, Chembiochem : a European journal of chemical biology.