Peng Li

发表

Discovery and Preclinical Pharmacology of an Oral Bromodomain and Extra-Terminal (BET) Inhibitor Using Scaffold-Hopping and Structure-Guided Drug Design.

Vijay T. Ahuja, Derek J. Norris, J. Tokarski, 2021, Journal of medicinal chemistry.

Azatricyclic Inverse Agonists of RORγt That Demonstrate Efficacy in Models of Rheumatoid Arthritis and Psoriasis.

Michael G. Yang, D. Shuster, C. Weigelt, 2021, ACS medicinal chemistry letters.

Driving Potency with Rotationally Stable Atropisomers: Discovery of Pyridopyrimidinedione-Carbazole Inhibitors of BTK.

Michael A. Galella, K. McIntyre, J. Barrish, 2020, ACS medicinal chemistry letters.

Large‐scale chiral supercritical fluid chromatography of a key intermediate in the synthesis of two S1P 1 final active pharmaceutical ingredients

A. Mathur, P. Li, Dawn Sun, 2019, SEPARATION SCIENCE PLUS.

Additive free preparative chiral SFC separations of 2,2-dimethyl-3-aryl-propanoic acids.

A. Mathur, P. Li, Dawn Sun, 2016, Journal of pharmaceutical and biomedical analysis.

Development of the Large-Scale Synthesis of Tetrahydropyran Glycine, a Precursor to the HCV NS5A Inhibitor BMS-986097.

A. Mathur, N. Meanwell, P. Li, 2017, The Journal of organic chemistry.

Discovery of 6-Fluoro-5-(R)-(3-(S)-(8-fluoro-1-methyl-2,4-dioxo-1,2-dihydroquinazolin-3(4H)-yl)-2-methylphenyl)-2-(S)-(2-hydroxypropan-2-yl)-2,3,4,9-tetrahydro-1H-carbazole-8-carboxamide (BMS-986142): A Reversible Inhibitor of Bruton's Tyrosine Kinase (BTK) Conformationally Constrained by Two Locked

Michael A. Galella, K. McIntyre, J. Barrish, 2016, Journal of medicinal chemistry.

Separation of Bruton's tyrosine kinase inhibitor atropisomers by supercritical fluid chromatography.

A. Mathur, Peng Li, J. Tino, 2019, Journal of chromatography. A.

Identification of Imidazo[1,2-b]pyridazine Derivatives as Potent, Selective, and Orally Active Tyk2 JH2 Inhibitors.

James Lin, K. McIntyre, J. Tokarski, 2019, ACS medicinal chemistry letters.

Enantioselective synthesis of BMS-911278: a triple reuptake inhibitor

A. Mathur, Paul C. Lobben, Shuang Liu, 2017 .

Discovery of a Highly Selective JAK2 Inhibitor, BMS-911543, for the Treatment of Myeloproliferative Neoplasms.

J. Tokarski, G. Trainor, A. Mathur, 2015, ACS medicinal chemistry letters.

Identification of Tricyclic Agonists of Sphingosine-1-phosphate Receptor 1 (S1P1) Employing Ligand-Based Drug Design.

K. McIntyre, D. Shuster, D. Shen, 2016, Journal of medicinal chemistry.

Rationally Designed, Conformationally Constrained Inverse Agonists of RORγt ‒ Identification of a Potent, Selective Series with Biologic-Like In Vivo Efficacy.

K. McIntyre, D. Shuster, J. Macor, 2019, Journal of medicinal chemistry.

Evolution of a Scale-Up Synthesis to a Potent GluN2B Inhibitor and Its Prodrug

Michael A. Galella, A. Mathur, M. Dabros, 2018, Organic Process Research & Development.

Sub/supercritical Fluid Chromatography Purification and Desalting of a Cyclic Dinucleotide STING Agonist.

A. Mathur, Dawn Sun, Dauh-Rurng Wu, 2021, Journal of chromatography. A.

Asymmetric Hydroboration Approach to the Scalable Synthesis of ((1R,3S)-1-Amino-3-((R)-6-hexyl-5,6,7,8-tetrahydronaphthalen-2-yl)cyclopentyl)methanol (BMS-986104) as a Potent S1P1 Receptor Modulator.

Michael G. Yang, K. McIntyre, D. Shen, 2016, Journal of medicinal chemistry.

Tricyclic Sulfones as Potent, Selective and Efficacious RORγt Inverse Agonists - Exploring C6 and C8 SAR Using Late-Stage Functionalization.

Michael G. Yang, D. Shuster, C. Weigelt, 2020, Bioorganic & medicinal chemistry letters.

The Discovery of GSK3640254, a Next-Generation Inhibitor of HIV-1 Maturation.

A. Mathur, N. Meanwell, Zeyu Lin, 2022, Journal of medicinal chemistry.

Large-scale supercritical fluid chromatography purification of unstable STING agonist intermediates.

A. Mathur, Dawn Sun, Dauh-Rurng Wu, 2021, Journal of chromatography. A.

Reverse-phase HPLC purification for an extremely unstable glucuronide metabolite.

A. Mathur, Peng Li, Dawn Sun, 2020, Journal of pharmaceutical and biomedical analysis.

From analytical methods to large scale chiral supercritical fluid chromatography using chlorinated chiral stationary phases.

A. Mathur, P. Li, Dawn Sun, 2016, Journal of chromatography. A.