I. Chachoua

发表

WNT signaling and AHCTF1 promote oncogenic MYC expression through super-enhancer-mediated gene gating

R. Ohlsson, Noriyuki Sumida, A. Göndör, 2019, Nature Genetics.

Calreticulin mutants in mice induce an MPL-dependent thrombocytosis with frequent progression to myelofibrosis.

C. Pecquet, W. Vainchenker, H. Raslova, 2016, Blood.

Thrombopoietin receptor activation by myeloproliferative neoplasm associated calreticulin mutants.

C. Pecquet, P. Courtoy, W. Vainchenker, 2016, Blood.

Calreticulin mutants as oncogenic rogue chaperones for TpoR and traffic-defective pathogenic TpoR mutants.

D. Vertommen, C. Pecquet, W. Vainchenker, 2019, Blood.

Oncogenic activation of MPL/thrombopoietin receptor by 17 mutations at W515: implications for myeloproliferative neoplasms

C. Pecquet, S. Constantinescu, J. Defour, 2016, Leukemia.

Persistent STAT5 activation in myeloid neoplasms recruits p53 into gene regulation

C. Pecquet, S. Constantinescu, A. Green, 2014, Oncogene.

A p53-JAK-STAT connection involved in myeloproliferative neoplasm pathogenesis and progression to secondary acute myeloid leukemia.

C. Pecquet, S. Constantinescu, W. Vainchenker, 2020, Blood reviews.

MPL Mutations in Essential Thrombocythemia Uncover A Common Path of Activation with Eltrombopag Dependent on W491.

S. Carillo, Steven O. Smith, L. Varghese, 2020, Blood.

Canonical WNT signaling-dependent gating of MYC requires a noncanonical CTCF function at a distal binding site

Shuangyang Wu, A. Göndör, Barbara A Scholz, 2022, Nature Communications.

Presence of atypical thrombopoietin receptor (MPL) mutations in triple-negative essential thrombocythemia patients.

W. Vainchenker, N. Debili, R. Favier, 2016, Blood.

Whole-exome sequencing identifies novel MPL and JAK2 mutations in triple-negative myeloproliferative neoplasms.

M. Cazzola, C. Bock, R. Kralovics, 2015, Blood.

Calr Mutants Retroviral Mouse Models Lead to a Myeloproliferative Neoplasm Mimicking an Essential Thrombocythemia Progressing to a Myelofibrosis

C. Pecquet, W. Vainchenker, R. Kralovics, 2014 .

Oncogenic CALR mutant C-terminus mediates dual binding to the thrombopoietin receptor triggering complex dimerization and activation

G. Mazzucchelli, D. Vertommen, C. Pecquet, 2023, Nature Communications.

Pathologic activation of thrombopoietin receptor and JAK2-STAT5 pathway by frameshift mutants of mouse calreticulin

C. Pecquet, W. Vainchenker, R. Kralovics, 2016, Leukemia.

Secreted Mutant Calreticulins As Rogue Cytokines in Myeloproliferative Neoplasms.

M. Cazzola, D. Vertommen, C. Pecquet, 2022, Blood.

Secreted Mutant Calreticulins As Rogue Cytokines Trigger Thrombopoietin Receptor Activation Specifically in CALR Mutated Cells: Perspectives for MPN Therapy

M. Cazzola, C. Pecquet, W. Vainchenker, 2018, Blood.

Crispr/Cas9 Engineered 61bp Deletion in the Calr Gene of Mice Leads to Development of Thrombocytosis

C. Pecquet, Y. Achouri, S. Constantinescu, 2016 .

Canonical WNT signaling-dependent gating of MYC requires a noncanonical CTCF function at a distal binding site

Shuangyang Wu, A. Göndör, Barbara A Scholz, 2022, Nature communications.

Levels of malondialdehyde and magnesium and the activity of catalase and glutathione reductase as markers of oxidative stress in the erythrocytes of patients with Ischemic Heart Disease

I. Chachoua, S. Konoshenko, V. Kazakova, 2010 .

Recent Advances towards the Understanding of Secondary Acute Myeloid Leukemia Progression

Upendarrao Golla, I. Chachoua, Scott Auerbach, 2024, Life.